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The map label for this gene is ruvA [H]

Identifier: 209695355

GI number: 209695355

Start: 2023519

End: 2024139

Strand: Direct

Name: ruvA [H]

Synonym: VSAL_I1888

Alternate gene names: 209695355

Gene position: 2023519-2024139 (Clockwise)

Preceding gene: 209695354

Following gene: 209695356

Centisome position: 60.85

GC content: 40.26

Gene sequence:

>621_bases
GTGATCGGACGCCTTCGTGGAAATCTATTAGAAAAACAACCACCAGAATTACTCATTGAAGTCAGTGGTATTGGTTATGA
AGTTCAAATGCCAATGAGTTGTTTTTATGAATTACCACCGATTGGTACCGAAGCCATTATCTATATTCATTATGTAGTAC
GTGAAGATGCTCAATTACTTTACGGTTTTAATACTAAAAAAGAACGAGCGTTATTTAGAGAAGTGATCAAAGCTAACGGG
GTGGGGCCAAAACTTGGTTTGGCGATACTGTCTGGCATGACTGCTTCTCAATTTGTTCAAAGTGTTGAGCGTGAAGATAT
TTCGACCTTAGTCAAATTACCAGGTGTTGGTAAAAAAACGGCAGAGCGTTTAGTCGTAGAGATGAAAGATCGCCTAAAAG
GGTGGGGAGCGGGTGACTTATTTACTCCAGCAGACACTACGTCAATGGATGATGCTTCTGATTTGATTTCATCGCCTCAA
AGCGCACAAGATGAAGCAGTCAGTGCGCTTATTTCTTTAGGCTATAAACCAGTGCAGGCGTCTAAAATGGTATCTCAAGT
CGCAAAACCTGATATGACCAGTGAATCTCTAATTCGTGAATCATTGAAATCAATGATCTAA

Upstream 100 bases:

>100_bases
CTAGATAAAAGAGGGAATAAATTCTCATTTCTTTTACTGGATATCTATCCAGTTCTTTATTACTATCCTAACCAGTTAAT
TATTTTAAAGAGTATCTATT

Downstream 100 bases:

>100_bases
CTTTATTTATCGCCTCTTTACTTACAGAATTTTTTGAGACCTTTTATGATTGAAGCCGATCGCCTTATTGCTGCTGATAA
CCCTGTTTTTCGTGACGAAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPPIGTEAIIYIHYVVREDAQLLYGFNTKKERALFREVIKANG
VGPKLGLAILSGMTASQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPADTTSMDDASDLISSPQ
SAQDEAVSALISLGYKPVQASKMVSQVAKPDMTSESLIRESLKSMI

Sequences:

>Translated_206_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPPIGTEAIIYIHYVVREDAQLLYGFNTKKERALFREVIKANG
VGPKLGLAILSGMTASQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPADTTSMDDASDLISSPQ
SAQDEAVSALISLGYKPVQASKMVSQVAKPDMTSESLIRESLKSMI
>Mature_206_residues
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPPIGTEAIIYIHYVVREDAQLLYGFNTKKERALFREVIKANG
VGPKLGLAILSGMTASQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPADTTSMDDASDLISSPQ
SAQDEAVSALISLGYKPVQASKMVSQVAKPDMTSESLIRESLKSMI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=211, Percent_Identity=64.9289099526066, Blast_Score=284, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22524; Mature: 22524

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPPIGTEAIIYIHYVVREDAQLL
CCCCCCCCHHCCCCCCEEEEECCCCEEEECHHHHHHCCCCCCCHHEEEHHHHHHCCHHHH
YGFNTKKERALFREVIKANGVGPKLGLAILSGMTASQFVQSVEREDISTLVKLPGVGKKT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKGWGAGDLFTPADTTSMDDASDLISSPQSAQDEAVSALISLGYKPVQA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
SKMVSQVAKPDMTSESLIRESLKSMI
HHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPPIGTEAIIYIHYVVREDAQLL
CCCCCCCCHHCCCCCCEEEEECCCCEEEECHHHHHHCCCCCCCHHEEEHHHHHHCCHHHH
YGFNTKKERALFREVIKANGVGPKLGLAILSGMTASQFVQSVEREDISTLVKLPGVGKKT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKGWGAGDLFTPADTTSMDDASDLISSPQSAQDEAVSALISLGYKPVQA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
SKMVSQVAKPDMTSESLIRESLKSMI
HHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA