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The map label for this gene is fnr [H]

Identifier: 209695074

GI number: 209695074

Start: 1682324

End: 1683076

Strand: Direct

Name: fnr [H]

Synonym: VSAL_I1571

Alternate gene names: 209695074

Gene position: 1682324-1683076 (Clockwise)

Preceding gene: 209695073

Following gene: 209695075

Centisome position: 50.59

GC content: 38.91

Gene sequence:

>753_bases
ATGATGTCAGATAACTCAGCAAACAAACGAATTCAATCAGGTGGGTGTGCTATTCACTGTCAAGATTGCAGTATCAGTCA
ATTATGTATACCGTTCACATTAAATGAATCGGAATTAGATCAGCTAGATGAAATCATCGAGCGCAAAAAGCCGATTCAAA
AAGGCCAAGAACTGTTTAAAGCGGGTGATGAACTAAAATCACTGTATGCAATTCGTTCAGGTACAATCAAGAGCTACACC
ATTACTGAACAAGGTGATGAGCAAATTACCGCTTTTCATTTAGCGGGTGATTTGGTTGGTTTTGATGCGATTACTGATGC
TGAACACCCAAGCTTTGCTCAAGCACTTGAAACATCAATGGTATGTGAAATACCTTATGAAATTTTAGATGACCTTTCAG
GTAAAATGCCTAAGCTCCGTCAACAAATTATGCGTTTAATGAGTAATGAAATTAAAGGTGACCAAGAAATGATCCTTCTG
CTTTCTAAAAAGAACGCAGAAGAGCGCTTAGCGGCTTTCTTGTTTAACTTATCGACTCGTTTCCACCAACGTGGTTTTTC
ACCTCGCGAATTCCGTCTTACTATGACTCGTGGTGATATTGGTAACTACCTTGGCCTAACCGTAGAAACAATCAGTCGCC
TACTTGGCCGCTTTCAAAAAACAGAAATGTTAACGGTAAAAGGCAAGTATATAACCATAAATGATCATGATGCATTAGCC
GAACTTGCAGGTTCAGTTAAAGCAATAAAATAG

Upstream 100 bases:

>100_bases
CTAATTATATTTTTTTTGCATTGTTTTGTATTTATGCTACCACTTTAGGACTGGTTGATGCTAAAATTGACTTATATCAA
TTATAAGAGCATTGAATGAG

Downstream 100 bases:

>100_bases
CCTCTGTTATTTTGAAACACATCTCATAGTGAGGCACTTCTCTTTGAAGTACCTCACTTTTTTATATCTAATTCCCCCCA
ATACTCTCCCTACCTGCTAA

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDEIIERKKPIQKGQELFKAGDELKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITDAEHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLFNLSTRFHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALA
ELAGSVKAIK

Sequences:

>Translated_250_residues
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDEIIERKKPIQKGQELFKAGDELKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITDAEHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLFNLSTRFHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALA
ELAGSVKAIK
>Mature_250_residues
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDEIIERKKPIQKGQELFKAGDELKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITDAEHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLFNLSTRFHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALA
ELAGSVKAIK

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=249, Percent_Identity=84.7389558232932, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28059; Mature: 28059

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDEIIERKKPIQKGQELFK
CCCCCCCHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDELKSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITDAEHPSFAQALETSM
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLFNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
FHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALA
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCHHHHH
ELAGSVKAIK
HHHHHHCCCC
>Mature Secondary Structure
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDEIIERKKPIQKGQELFK
CCCCCCCHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDELKSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITDAEHPSFAQALETSM
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLFNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
FHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALA
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCHHHHH
ELAGSVKAIK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA