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The map label for this gene is dcuC [H]

Identifier: 209694436

GI number: 209694436

Start: 956160

End: 957527

Strand: Reverse

Name: dcuC [H]

Synonym: VSAL_I0857

Alternate gene names: 209694436

Gene position: 957527-956160 (Counterclockwise)

Preceding gene: 209694439

Following gene: 209694435

Centisome position: 28.8

GC content: 42.47

Gene sequence:

>1368_bases
ATGTTGGAGTTAATGATTGGTTTAGTGATCACCGTTTTGGTTGGTTACTTTATTGTCAAAGGATATAAGGCTGCCGGTGT
TCTACTGACTGCGGGTTTAGCGTTATTAATGATTGCGGGTTTATTAGGCCATACTGTTTTACCGGCTAAAGTTGCGACAA
CAGGTAACTTATTAACCGACGCATTAGAATACGTGAAATACATGCTGCAATATCGTGGGGGCGGCTTGGGTATGCAAATC
ATGCTACTTTGTGGTTTTGCTTCTTATATGACTCACATTGGCGCAAATAATGTCGTTGTTAAACAATTTTCTAAACCATT
AGCATTTATTAAATCACCTTATGTGTTACTTGTAGCGGCTTACATTGTGGCATGTTTAATGTCCCTTGCTGTAAGTTCGG
CAACAGGTCTTGGTGTGCTGTTAATGGCAACCCTTTTCCCAATGATGACAGCAATGGGTATTTCTCGCCCAGCAGCAGTA
GCCGTTTGTGCTTCACCAGCCGCAATCATTCTTTCTCCGACTTCTGGTGATGTTATTGTTGCAGCAGAAAAGTCTGGCCT
TCCTTTACATACCTTTGCGGTTGAAACGGTATTACCTGTTTCTATCTGTGCAATCATTGTAATGGCCGCCGCCGCTTTCT
TCTGGAACAAGTATCTAGATAAGAAAGAAAACACGCCAATGGAAAAAGTGGATATTTCGGCAATGGAAGTAAACGCGCCG
TCTTATTACGCGATTTTGCCTTTCTTGCCAATTGTGGGTGTTTTTATCTTCAACGGCCAAACTATCCCTGGTTTATCTTT
AGATATTTATACTATCGTTGTAGCGTCTATCTTTATTGGCGCGATCGTCAATTTCATTACTAACCGCTTTAACGGCAGAG
CAACACTTGAAGATTTAGAATCATGCTACGAAGGCATGGCCGATGCATTTAAAGGCGTGGTAATGCTATTGGTAGCCGCT
GGCGTATTTGCACAAGGTCTAATGTCAGTAGGTGCCATTGATAACCTACTTCACCTTGCTGATTCTGCTGGTGCTGGTGG
TATGGCGTTAATGCTTCTTCTTACTGGTTTAACCGTAGCCGCTGCAATTGCTACCGGTTCTGGTAACGCACCATTTTATG
CCTTTGTTGAGCTTGCTCCACAACTTGCTGATAAAATGGGTCTAAGCCCTGCATTCTTAATCATTCCGATGCTTCAAGCA
TCTAACCTTGGTCGTACTATTTCACCGGTATCTGGTGTTATTGTTGCGACATCTGGTATGGCTAAAATCAGTCCATTTGA
AGTAGTTAAACGTACCTCTGTTCCTGTTATCTGCGGTTTAATTACGGTTATCGTAGGCACAATGGTACTGGTTCCTATGT
ACGTATAA

Upstream 100 bases:

>100_bases
CAAACAAAACTTAGGTAAGTTTCTATTATGAAATGTGTAAGAAAATGTATGTAAGTTACACAATTTTTGTATTTTTGAAA
CTTTATTAGAAGGAAATTCC

Downstream 100 bases:

>100_bases
TTAAGTAAAAAGTGATATTAACGCCAGTAGTGTAAAAGTACTGGCGTTTTTTATTATAGTAGGCACCTTTATCACAAAGA
ATTTACAGTTTGCTCACCCA

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLELMIGLVITVLVGYFIVKGYKAAGVLLTAGLALLMIAGLLGHTVLPAKVATTGNLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYVLLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHTFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFIFNGQTIPGLSLDIYTIVVASIFIGAIVNFITNRFNGRATLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADSAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLADKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIVGTMVLVPMYV

Sequences:

>Translated_455_residues
MLELMIGLVITVLVGYFIVKGYKAAGVLLTAGLALLMIAGLLGHTVLPAKVATTGNLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYVLLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHTFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFIFNGQTIPGLSLDIYTIVVASIFIGAIVNFITNRFNGRATLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADSAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLADKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIVGTMVLVPMYV
>Mature_455_residues
MLELMIGLVITVLVGYFIVKGYKAAGVLLTAGLALLMIAGLLGHTVLPAKVATTGNLLTDALEYVKYMLQYRGGGLGMQI
MLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYVLLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAV
AVCASPAAIILSPTSGDVIVAAEKSGLPLHTFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
SYYAILPFLPIVGVFIFNGQTIPGLSLDIYTIVVASIFIGAIVNFITNRFNGRATLEDLESCYEGMADAFKGVVMLLVAA
GVFAQGLMSVGAIDNLLHLADSAGAGGMALMLLLTGLTVAAAIATGSGNAPFYAFVELAPQLADKMGLSPAFLIIPMLQA
SNLGRTISPVSGVIVATSGMAKISPFEVVKRTSVPVICGLITVIVGTMVLVPMYV

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=436, Percent_Identity=62.1559633027523, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1789622, Length=454, Percent_Identity=36.3436123348018, Blast_Score=287, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47426; Mature: 47426

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELMIGLVITVLVGYFIVKGYKAAGVLLTAGLALLMIAGLLGHTVLPAKVATTGNLLTD
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHH
ALEYVKYMLQYRGGGLGMQIMLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYVLLVAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHH
YIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAVAVCASPAAIILSPTSGDVIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEE
AAEKSGLPLHTFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCC
SYYAILPFLPIVGVFIFNGQTIPGLSLDIYTIVVASIFIGAIVNFITNRFNGRATLEDLE
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SCYEGMADAFKGVVMLLVAAGVFAQGLMSVGAIDNLLHLADSAGAGGMALMLLLTGLTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAIATGSGNAPFYAFVELAPQLADKMGLSPAFLIIPMLQASNLGRTISPVSGVIVATSGM
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
AKISPFEVVKRTSVPVICGLITVIVGTMVLVPMYV
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLELMIGLVITVLVGYFIVKGYKAAGVLLTAGLALLMIAGLLGHTVLPAKVATTGNLLTD
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHH
ALEYVKYMLQYRGGGLGMQIMLLCGFASYMTHIGANNVVVKQFSKPLAFIKSPYVLLVAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHH
YIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAVAVCASPAAIILSPTSGDVIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEE
AAEKSGLPLHTFAVETVLPVSICAIIVMAAAAFFWNKYLDKKENTPMEKVDISAMEVNAP
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCC
SYYAILPFLPIVGVFIFNGQTIPGLSLDIYTIVVASIFIGAIVNFITNRFNGRATLEDLE
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SCYEGMADAFKGVVMLLVAAGVFAQGLMSVGAIDNLLHLADSAGAGGMALMLLLTGLTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAIATGSGNAPFYAFVELAPQLADKMGLSPAFLIIPMLQASNLGRTISPVSGVIVATSGM
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
AKISPFEVVKRTSVPVICGLITVIVGTMVLVPMYV
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]