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The map label for this gene is lolB [H]

Identifier: 209694370

GI number: 209694370

Start: 874388

End: 874999

Strand: Reverse

Name: lolB [H]

Synonym: VSAL_I0788

Alternate gene names: 209694370

Gene position: 874999-874388 (Counterclockwise)

Preceding gene: 209694377

Following gene: 209694369

Centisome position: 26.31

GC content: 38.56

Gene sequence:

>612_bases
ATGCTACGCCGTCCTCTTTCTTTTTTTGCTTCCGTTTTCTTTCTGCTGTTTTTTCTCAGCGCTTGTTCTACGACCCCATT
AACCCCACAACAGTCAACTAATTGGAATAAACATCAATCTAATATTGAGCAATTAACTCAGTATAAAGTGACAGGGAAAA
TTGGATATCAAGACCTAGAACAACGCCACAGCCTCAACTTCCAATGGACTCAAAAGGAAGATAACAGTCAATTGTTGCTC
ACCACATTTCTTGGGCAAACCATAATGAAACTGACGTTATCCAAAAATAAAGCCACCATTGAAACCGGCGATGGTAAGAA
ATTTGAAGGTAATGATCCGGGACGCTTACTATACGGATTAACGGGCATGACAATTCCTATCGCCTACCTAAGTGATTGGC
TTAAAGGGTTACCAACCTCTGCAGATGCATTTGAACTCAATGAATTAAATACCGTAGAGCACCTATCAAAACAAATCAGT
CAAACCAATTGGCATCTTAGATATAACAGCTATATCGAAACCAATGGGTTACTGCTGCCGAATTCAATGAAATTGACACA
AAAAGACACCACAATAAAAATCATTGCTTCAAATTGGATTATATCTCAATGA

Upstream 100 bases:

>100_bases
ATATTTAACCTACTTATTGTGTAAATCTTGATACCCAAACAATCAATGGATTTGATACAATCCTATAATCTGTCTCGAAT
TAACAGTGAGTTCTTTATTT

Downstream 100 bases:

>100_bases
TAACGACAGCAACTCGCTGGCCTTCTCCAGCTAAACTCAATTTATTCCTGTATATAAATGGGCAGCATGATAATGGTTAT
CATGAATTACAGACCCTTTT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLRRPLSFFASVFFLLFFLSACSTTPLTPQQSTNWNKHQSNIEQLTQYKVTGKIGYQDLEQRHSLNFQWTQKEDNSQLLL
TTFLGQTIMKLTLSKNKATIETGDGKKFEGNDPGRLLYGLTGMTIPIAYLSDWLKGLPTSADAFELNELNTVEHLSKQIS
QTNWHLRYNSYIETNGLLLPNSMKLTQKDTTIKIIASNWIISQ

Sequences:

>Translated_203_residues
MLRRPLSFFASVFFLLFFLSACSTTPLTPQQSTNWNKHQSNIEQLTQYKVTGKIGYQDLEQRHSLNFQWTQKEDNSQLLL
TTFLGQTIMKLTLSKNKATIETGDGKKFEGNDPGRLLYGLTGMTIPIAYLSDWLKGLPTSADAFELNELNTVEHLSKQIS
QTNWHLRYNSYIETNGLLLPNSMKLTQKDTTIKIIASNWIISQ
>Mature_203_residues
MLRRPLSFFASVFFLLFFLSACSTTPLTPQQSTNWNKHQSNIEQLTQYKVTGKIGYQDLEQRHSLNFQWTQKEDNSQLLL
TTFLGQTIMKLTLSKNKATIETGDGKKFEGNDPGRLLYGLTGMTIPIAYLSDWLKGLPTSADAFELNELNTVEHLSKQIS
QTNWHLRYNSYIETNGLLLPNSMKLTQKDTTIKIIASNWIISQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=205, Percent_Identity=30.2439024390244, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 23199; Mature: 23199

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRPLSFFASVFFLLFFLSACSTTPLTPQQSTNWNKHQSNIEQLTQYKVTGKIGYQDLE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
QRHSLNFQWTQKEDNSQLLLTTFLGQTIMKLTLSKNKATIETGDGKKFEGNDPGRLLYGL
HHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEEEC
TGMTIPIAYLSDWLKGLPTSADAFELNELNTVEHLSKQISQTNWHLRYNSYIETNGLLLP
CCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHCCCEEEEECCEEECCCEECC
NSMKLTQKDTTIKIIASNWIISQ
CCCEEECCCCEEEEEECCCEECC
>Mature Secondary Structure
MLRRPLSFFASVFFLLFFLSACSTTPLTPQQSTNWNKHQSNIEQLTQYKVTGKIGYQDLE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
QRHSLNFQWTQKEDNSQLLLTTFLGQTIMKLTLSKNKATIETGDGKKFEGNDPGRLLYGL
HHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEEEC
TGMTIPIAYLSDWLKGLPTSADAFELNELNTVEHLSKQISQTNWHLRYNSYIETNGLLLP
CCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHCCCEEEEECCEEECCCEECC
NSMKLTQKDTTIKIIASNWIISQ
CCCEEECCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA