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The map label for this gene is ywbA [H]

Identifier: 209694292

GI number: 209694292

Start: 790040

End: 791326

Strand: Direct

Name: ywbA [H]

Synonym: VSAL_I0703

Alternate gene names: 209694292

Gene position: 790040-791326 (Clockwise)

Preceding gene: 209694289

Following gene: 209694293

Centisome position: 23.76

GC content: 40.87

Gene sequence:

>1287_bases
ATGAGTACGCAAGCGGCAACGATGCAAAGCACAATAATGGAGAAGGTAAACAAAATCCTTCCTAAGCTCTTAAAGGTAGT
GAATTCAAAACCAATTGTAGCCATTAAAGAAGGCTTCATGTTAACCATGCCATTGACCATCATTGGCTCGGTATTCTTGT
TATTGGCCTTTGTTCCTATTGATGGCTATGACCAATTTATGGCGGGAATTTTTGGTGCTGAATGGTCAACACCATTGTTT
CAAGTTGTTGGCGCTACTTTTGATATTTTGGCACTGATTGGAGCTTTTGGTATTGCGTATACTTACGTGAAGTATGAAGG
ACACAATGGCGTAAATGCGGGGGTGTTAGCCATTGTTTCTTTACTTATCGTAATGAACGCTTTTGTTGTGGCGCCAGATG
GCGTGAGGCACATAGGTGGAGTGATACCGAAAGCCTTCCTTGGTGGTAAAGGCATGATTGCAGCTATCGTTATTGGTTTA
GTTGTTGGCATGATTTACTCAATGGCCTTTAACCGTAACTGGGTGATTAAACTGCCAGACAGCGTGCCAGAAGGGGTGTC
GAATGCTTTTAAATCGCTTATTCCTGGTTTTTTAATTATCACTCTTGCTTTCTTAACATACATATTTTTTGAAGTAGTTT
TTGAAAGAACGTTTATTGAGACTATTTACCATATTATTCAAACACCATTACAAAGTATGTCTGATTCTTTCTTTGGTGCG
GTAGGTATTGCATTGCTTATTTCTCTACTTTGGTGGTGTGGTGTTCATGGCCCCGTCATTGTTATGGGAATTATGGGACC
AATCGTAACGGCGAATGCACTCCATAATCAATCAATTGTAAATGCGGGTGAAGTACTGATTGCAGGTGAGAATGGAAAAA
TAGTAACGAACCAATTTGTTGACCAATTTATTACGGTCGGTGGCTCAGGACTTACCTTCGGCTTAGTGTGTTGCATGGTC
TTATTTGCTCGCTCTGTTCAGTTTAAGCAATTAGGTCGTCTCTCTTTTATCCCAGGCATTTTTAATATCAATGAGCCCGT
AATTTTCGCAACACCAATCATCTTTAACCCAATTATGTTTATTCCATTTGTGACTGCTCCAGTGCTGTCAGCAATCATGG
TTTATACCTCAATTAACATGGGGTTTGTTGGACCATTCACGGCCGTTCAAGTGCCATGGACAACGCCAATAGTATTGAGT
GGATTTATTGTTGGGGGGGTGGAGTGCCGCTGTATTACAAGTCACCGTGTTCTGTATGACGTTATGTGTGTATTTCCCAT
TCTTTAA

Upstream 100 bases:

>100_bases
AACTTGCTCAATTATGGCGTGTAACCGGTTACTGAAACCGGTTACATTGATTTCAGGTTAAATTAATTCGCATGTTTAAA
ATTCAATTCAGGGGTGAAAA

Downstream 100 bases:

>100_bases
GTATCTAGACAAATTAACGGCGCAAGAAGAAGCTAAATCAACAGCGCCAGAAACAGAATCTGTAACAACGACAGCAACAG
CTTAATTGAAATTTATTAGA

Product: PTS system, cellobiose permease IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSTQAATMQSTIMEKVNKILPKLLKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYDQFMAGIFGAEWSTPLF
QVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVRHIGGVIPKAFLGGKGMIAAIVIGL
VVGMIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEVLIAGENGKIVTNQFVDQFITVGGSGLTFGLVCCMV
LFARSVQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPIVLS
GFIVGGVECRCITSHRVLYDVMCVFPIL

Sequences:

>Translated_428_residues
MSTQAATMQSTIMEKVNKILPKLLKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYDQFMAGIFGAEWSTPLF
QVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVRHIGGVIPKAFLGGKGMIAAIVIGL
VVGMIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEVLIAGENGKIVTNQFVDQFITVGGSGLTFGLVCCMV
LFARSVQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPIVLS
GFIVGGVECRCITSHRVLYDVMCVFPIL
>Mature_427_residues
STQAATMQSTIMEKVNKILPKLLKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPIDGYDQFMAGIFGAEWSTPLFQ
VVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVSLLIVMNAFVVAPDGVRHIGGVIPKAFLGGKGMIAAIVIGLV
VGMIYSMAFNRNWVIKLPDSVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGAV
GIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEVLIAGENGKIVTNQFVDQFITVGGSGLTFGLVCCMVL
FARSVQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMFIPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPIVLSG
FIVGGVECRCITSHRVLYDVMCVFPIL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=409, Percent_Identity=33.7408312958435, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 46212; Mature: 46081

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQAATMQSTIMEKVNKILPKLLKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHHHHHHHHHCCC
DGYDQFMAGIFGAEWSTPLFQVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
LLIVMNAFVVAPDGVRHIGGVIPKAFLGGKGMIAAIVIGLVVGMIYSMAFNRNWVIKLPD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEVLIAGENGKIVTNQFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEECCCCCEEHHHHH
DQFITVGGSGLTFGLVCCMVLFARSVQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMF
HHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCCEEEECHHHHHHHHH
IPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPIVLSGFIVGGVECRCITSHRVLYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEEHHHHHHH
VMCVFPIL
HHHHHHCC
>Mature Secondary Structure 
STQAATMQSTIMEKVNKILPKLLKVVNSKPIVAIKEGFMLTMPLTIIGSVFLLLAFVPI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECHHHHHHHHHHHHHCCC
DGYDQFMAGIFGAEWSTPLFQVVGATFDILALIGAFGIAYTYVKYEGHNGVNAGVLAIVS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
LLIVMNAFVVAPDGVRHIGGVIPKAFLGGKGMIAAIVIGLVVGMIYSMAFNRNWVIKLPD
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SVPEGVSNAFKSLIPGFLIITLAFLTYIFFEVVFERTFIETIYHIIQTPLQSMSDSFFGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIALLISLLWWCGVHGPVIVMGIMGPIVTANALHNQSIVNAGEVLIAGENGKIVTNQFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEECCCCCEEHHHHH
DQFITVGGSGLTFGLVCCMVLFARSVQFKQLGRLSFIPGIFNINEPVIFATPIIFNPIMF
HHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCCEEEECHHHHHHHHH
IPFVTAPVLSAIMVYTSINMGFVGPFTAVQVPWTTPIVLSGFIVGGVECRCITSHRVLYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEEHHHHHHH
VMCVFPIL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]