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The map label for this gene is nlpI [H]

Identifier: 209694195

GI number: 209694195

Start: 667099

End: 668082

Strand: Direct

Name: nlpI [H]

Synonym: VSAL_I0603

Alternate gene names: 209694195

Gene position: 667099-668082 (Clockwise)

Preceding gene: 209694194

Following gene: 209694199

Centisome position: 20.06

GC content: 36.79

Gene sequence:

>984_bases
GTGAATTGGATTCGAATTACGCTAGTCAGTGCCGTCTTAATATTATCAGGATGTGCATCAACAAAGGATTCTTCAAGTTG
GATGTACCCGCCAATGGCAGTGCCTTTACAACCGAGTATTCAGCAAGAGATTCAACTTTCTCGACTTAATCAATTATTAT
TACGCACTGATATTGACGACGTAACTCGTGCAAAAATGTTTTATGATCGTGGGTTAATAAATGACAGTTTAGGACTACGT
GACTTAGCGCGAGTGGACTTTACTCAGTCTTTAAATTTAAAACCAGATCAGAGTGATGTATTTAATATTTTGGGTGTTTA
CTACACGCAAAATACCGATTTTGATGGTGCTTATGAAGCCTTCGATTCTGCCTTAGAATTAGATCCATCGAATCAATTTG
CAGAACGAAATTTAGCGATTGCCCTTTATTATGGTGAGCGTTATGACCAAGCTTATGAGATAGCAAAAAAACACTATAAT
GATGCACAAAGTGATCCGTACCGTGCTATTTGGTTATATTGGATTGGTTTAAATGTGGATGCAACAGCCGCAACAGAAGC
ATTTAAAATACAGTACCAAGAAAGAACAGATGAAGATTTTGGTTGGGATTTAGCGGGTGTTATTTTAAAAGAAACATCGG
ATGATGCTTTCTTTCAAAAAATCTTAACGACGACTCGAAATAATACCGCACTTGCTCAGAAACTAACAGAAGGGTACTTT
TACCTTGGTAAGCGTTATCAGTATGAAGGGGATTACCCTACTGCGATTGCATTATACAAGTTAGCTATGTCAAATAATGT
GTATGAATTTGTAGAACATCGTTACTCTTTCATTGAACTGGGTAATATTTTTAAAACGCTGCGTGAATTACAAGAACAAA
AACAGAAAGAACAGCAAGCGTTAGAAGTGAAAGAAAAGCAGAATAGCCCAGAGCAAGACAGTGTAGAAAAAGAAGAATTA
AAGAAGGAAGCGACTACTAAATAA

Upstream 100 bases:

>100_bases
TACAGTCTTTTGATGTAAAGCGTGTTATAAAGGGAGCAGAGATGCTCCCTTTTTTTTGCATCAGGGCGACTAAAAATAGA
TTTATTGTAGGAGATAATGA

Downstream 100 bases:

>100_bases
TATAGATTATTTAGTGGTTCATAATATAAAAAGCCCTTATTTTAAAAGGTAAGGGCTTTTTATTTATAGCGAAAACTCAC
TGCTACATTTGAACAGCAAG

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNWIRITLVSAVLILSGCASTKDSSSWMYPPMAVPLQPSIQQEIQLSRLNQLLLRTDIDDVTRAKMFYDRGLINDSLGLR
DLARVDFTQSLNLKPDQSDVFNILGVYYTQNTDFDGAYEAFDSALELDPSNQFAERNLAIALYYGERYDQAYEIAKKHYN
DAQSDPYRAIWLYWIGLNVDATAATEAFKIQYQERTDEDFGWDLAGVILKETSDDAFFQKILTTTRNNTALAQKLTEGYF
YLGKRYQYEGDYPTAIALYKLAMSNNVYEFVEHRYSFIELGNIFKTLRELQEQKQKEQQALEVKEKQNSPEQDSVEKEEL
KKEATTK

Sequences:

>Translated_327_residues
MNWIRITLVSAVLILSGCASTKDSSSWMYPPMAVPLQPSIQQEIQLSRLNQLLLRTDIDDVTRAKMFYDRGLINDSLGLR
DLARVDFTQSLNLKPDQSDVFNILGVYYTQNTDFDGAYEAFDSALELDPSNQFAERNLAIALYYGERYDQAYEIAKKHYN
DAQSDPYRAIWLYWIGLNVDATAATEAFKIQYQERTDEDFGWDLAGVILKETSDDAFFQKILTTTRNNTALAQKLTEGYF
YLGKRYQYEGDYPTAIALYKLAMSNNVYEFVEHRYSFIELGNIFKTLRELQEQKQKEQQALEVKEKQNSPEQDSVEKEEL
KKEATTK
>Mature_327_residues
MNWIRITLVSAVLILSGCASTKDSSSWMYPPMAVPLQPSIQQEIQLSRLNQLLLRTDIDDVTRAKMFYDRGLINDSLGLR
DLARVDFTQSLNLKPDQSDVFNILGVYYTQNTDFDGAYEAFDSALELDPSNQFAERNLAIALYYGERYDQAYEIAKKHYN
DAQSDPYRAIWLYWIGLNVDATAATEAFKIQYQERTDEDFGWDLAGVILKETSDDAFFQKILTTTRNNTALAQKLTEGYF
YLGKRYQYEGDYPTAIALYKLAMSNNVYEFVEHRYSFIELGNIFKTLRELQEQKQKEQQALEVKEKQNSPEQDSVEKEEL
KKEATTK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=295, Percent_Identity=42.7118644067797, Blast_Score=243, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 37823; Mature: 37823

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWIRITLVSAVLILSGCASTKDSSSWMYPPMAVPLQPSIQQEIQLSRLNQLLLRTDIDD
CCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
VTRAKMFYDRGLINDSLGLRDLARVDFTQSLNLKPDQSDVFNILGVYYTQNTDFDGAYEA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCCCHHHHH
FDSALELDPSNQFAERNLAIALYYGERYDQAYEIAKKHYNDAQSDPYRAIWLYWIGLNVD
HHHHHCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCC
ATAATEAFKIQYQERTDEDFGWDLAGVILKETSDDAFFQKILTTTRNNTALAQKLTEGYF
CHHHHHHHEEEEHHCCCCCCCCCHHHHEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YLGKRYQYEGDYPTAIALYKLAMSNNVYEFVEHRYSFIELGNIFKTLRELQEQKQKEQQA
HHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVKEKQNSPEQDSVEKEELKKEATTK
HHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNWIRITLVSAVLILSGCASTKDSSSWMYPPMAVPLQPSIQQEIQLSRLNQLLLRTDIDD
CCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
VTRAKMFYDRGLINDSLGLRDLARVDFTQSLNLKPDQSDVFNILGVYYTQNTDFDGAYEA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCCCHHHHH
FDSALELDPSNQFAERNLAIALYYGERYDQAYEIAKKHYNDAQSDPYRAIWLYWIGLNVD
HHHHHCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCC
ATAATEAFKIQYQERTDEDFGWDLAGVILKETSDDAFFQKILTTTRNNTALAQKLTEGYF
CHHHHHHHEEEEHHCCCCCCCCCHHHHEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
YLGKRYQYEGDYPTAIALYKLAMSNNVYEFVEHRYSFIELGNIFKTLRELQEQKQKEQQA
HHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVKEKQNSPEQDSVEKEELKKEATTK
HHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]