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The map label for this gene is lspA [H]

Identifier: 209694173

GI number: 209694173

Start: 640011

End: 640526

Strand: Direct

Name: lspA [H]

Synonym: VSAL_I0581

Alternate gene names: 209694173

Gene position: 640011-640526 (Clockwise)

Preceding gene: 209694172

Following gene: 209694174

Centisome position: 19.25

GC content: 40.5

Gene sequence:

>516_bases
ATGACTAGCGATAATAAGACATTACCGCTGCTTAAAGAATCTGGACTTCGCTGGCTATGGCTAGCGGGGTTGGTTTTTAT
GGCAGACATCAGCATTAAGTTATTTGTGATGAAAGAGATGACTTATGGTTGGGCGAACCGAATTGAAGTTTTGCCTTTCT
TTAATTTTCTTTACGCTCATAACTATGGTGCTGCATTTAGCTTTTTAAGTGATCAAGCCGGTTGGCAACGCTGGTTTTTT
ACCGGTATTGCTATCGTTGTATGTGGTTTACTTGCCTATTGGATGCGCAAAGCACCACAAACGGACAAGTTAAATAACAT
CGCGTATGCACTGATCATTGGTGGTGCGATTGGTAATGTGTTTGATCGCTTAGTTCATGGTTTTGTAGTGGATTATCTTG
ATTTCTATTGGGGTAGTTACCATTGGCCAACGTTCAACTTAGCGGATGCTGCGATTTGTATTGGTGCGGGATTGATCATC
TTAGATGGGTTTCGTTCTAATAAAAAAGAACAATAA

Upstream 100 bases:

>100_bases
ACCATGTTGCTGATGTAGGTACTATCGAAGGGCACGAAGAAGTGTGTGGTCGTTGTGTATCTAACGTTGAAGGCGAAGGC
GAAGAGCGTAAATTTGCATA

Downstream 100 bases:

>100_bases
GATAAAGTAAAAACATAAGCGCTGCCCGTGAATTCGAGGTGGCGTTTTTTTTAAGTGTTATACCAATATTATTGGTGTTA
TCTAAGGAAAGACAATGTCA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTSDNKTLPLLKESGLRWLWLAGLVFMADISIKLFVMKEMTYGWANRIEVLPFFNFLYAHNYGAAFSFLSDQAGWQRWFF
TGIAIVVCGLLAYWMRKAPQTDKLNNIAYALIIGGAIGNVFDRLVHGFVVDYLDFYWGSYHWPTFNLADAAICIGAGLII
LDGFRSNKKEQ

Sequences:

>Translated_171_residues
MTSDNKTLPLLKESGLRWLWLAGLVFMADISIKLFVMKEMTYGWANRIEVLPFFNFLYAHNYGAAFSFLSDQAGWQRWFF
TGIAIVVCGLLAYWMRKAPQTDKLNNIAYALIIGGAIGNVFDRLVHGFVVDYLDFYWGSYHWPTFNLADAAICIGAGLII
LDGFRSNKKEQ
>Mature_170_residues
TSDNKTLPLLKESGLRWLWLAGLVFMADISIKLFVMKEMTYGWANRIEVLPFFNFLYAHNYGAAFSFLSDQAGWQRWFFT
GIAIVVCGLLAYWMRKAPQTDKLNNIAYALIIGGAIGNVFDRLVHGFVVDYLDFYWGSYHWPTFNLADAAICIGAGLIIL
DGFRSNKKEQ

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=159, Percent_Identity=54.7169811320755, Blast_Score=179, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19497; Mature: 19366

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDNKTLPLLKESGLRWLWLAGLVFMADISIKLFVMKEMTYGWANRIEVLPFFNFLYAH
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHEEEEEHHHHHCHHHHHHHHHHHHHHHHC
NYGAAFSFLSDQAGWQRWFFTGIAIVVCGLLAYWMRKAPQTDKLNNIAYALIIGGAIGNV
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEEECCHHHHH
FDRLVHGFVVDYLDFYWGSYHWPTFNLADAAICIGAGLIILDGFRSNKKEQ
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TSDNKTLPLLKESGLRWLWLAGLVFMADISIKLFVMKEMTYGWANRIEVLPFFNFLYAH
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHEEEEEHHHHHCHHHHHHHHHHHHHHHHC
NYGAAFSFLSDQAGWQRWFFTGIAIVVCGLLAYWMRKAPQTDKLNNIAYALIIGGAIGNV
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEEECCHHHHH
FDRLVHGFVVDYLDFYWGSYHWPTFNLADAAICIGAGLIILDGFRSNKKEQ
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA