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The map label for this gene is xerD [H]

Identifier: 209694155

GI number: 209694155

Start: 616155

End: 617057

Strand: Direct

Name: xerD [H]

Synonym: VSAL_I0562

Alternate gene names: 209694155

Gene position: 616155-617057 (Clockwise)

Preceding gene: 209694153

Following gene: 209694156

Centisome position: 18.53

GC content: 39.42

Gene sequence:

>903_bases
ATGGTAATGAATAATGATATGGCGTTGATCGAGCGTTTTTTAGATACCATGTGGATGGAACGTGGATTATCTGAAAATAC
GTTGTCTTCTTATCGAAACGATTTAATGAAATTATTGAATTGGTTAGATGAGAATCACTATAAGTGTGCTTCTATCTCTG
CAATGGGATTAAATGAATACCAAGCTTATTTAGTTGATAAACAATATAAGCAAACATCTCGAGCTCGTATGCTTTCTGCT
TTGCGTCGATTTTTCCAGTATTTACATCGTGAAAAAATTAGAGGTGATGATCCTACCGCGTTATTAATGAGTCCCAAGTT
ACCGCAACGATTACCGAAAGATCTAAGTGAAGAACAAGTAAATGACTTACTGGAAGCGCCTAATGTCGATGATCCATTAG
AACTCCGTGATCGCGCTATGTTAGAACTACTTTACGCGACAGGTTTGCGTGTGACGGAATTAGTGAGTTTAACGATGGAA
AATTTGAGTTTACGTCAAGGTGTCGTACGAGTTACTGGTAAGGGAGATAAAGAGCGTTTGGTTCCAATGGGAGAGAACGC
GGTTTATTGGATTCAAACATTTTTAGATCAAGGTCGATCAACTCTATTGGGCGAAAAAAGCTCAGATGTGGTTTTTCCTA
GTCGACGTGCAAGACAAATGACAAGACAGACATTCTGGCATCGCATAAAGCATTATGCCGTAATTGCAGGGATTGATACG
GACAAATTATCGCCTCACGTTTTACGCCATGCTTTTGCGACACATTTGCTAAACTATGGGGCAGATCTTAGAGTCGTACA
AATGTTGTTGGGACATAGTGATCTTTCTACCACACAAATATATACTCATGTAGCAACAGAGCGTTTGAAACAGATACATC
AAGAGCATCACCCCCGTTCTTAA

Upstream 100 bases:

>100_bases
ACCGCAAATGATTCTTAAAATTAAACTTGCATTGAAAGTCAGTTAAATTGTTTAATACTGTAATTCTAACCAGTATTTCT
GGTATGCAGTCTTTGTGGTG

Downstream 100 bases:

>100_bases
TGAATGGGAACTTCTTGGTTTTTCTAAACTCTAATGATTTAAACGTTCTTACATCACACTTTTTTATAGGTAACCTTTTA
TGTCTTTTATTCGCCGTACT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MVMNNDMALIERFLDTMWMERGLSENTLSSYRNDLMKLLNWLDENHYKCASISAMGLNEYQAYLVDKQYKQTSRARMLSA
LRRFFQYLHREKIRGDDPTALLMSPKLPQRLPKDLSEEQVNDLLEAPNVDDPLELRDRAMLELLYATGLRVTELVSLTME
NLSLRQGVVRVTGKGDKERLVPMGENAVYWIQTFLDQGRSTLLGEKSSDVVFPSRRARQMTRQTFWHRIKHYAVIAGIDT
DKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS

Sequences:

>Translated_300_residues
MVMNNDMALIERFLDTMWMERGLSENTLSSYRNDLMKLLNWLDENHYKCASISAMGLNEYQAYLVDKQYKQTSRARMLSA
LRRFFQYLHREKIRGDDPTALLMSPKLPQRLPKDLSEEQVNDLLEAPNVDDPLELRDRAMLELLYATGLRVTELVSLTME
NLSLRQGVVRVTGKGDKERLVPMGENAVYWIQTFLDQGRSTLLGEKSSDVVFPSRRARQMTRQTFWHRIKHYAVIAGIDT
DKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
>Mature_300_residues
MVMNNDMALIERFLDTMWMERGLSENTLSSYRNDLMKLLNWLDENHYKCASISAMGLNEYQAYLVDKQYKQTSRARMLSA
LRRFFQYLHREKIRGDDPTALLMSPKLPQRLPKDLSEEQVNDLLEAPNVDDPLELRDRAMLELLYATGLRVTELVSLTME
NLSLRQGVVRVTGKGDKERLVPMGENAVYWIQTFLDQGRSTLLGEKSSDVVFPSRRARQMTRQTFWHRIKHYAVIAGIDT
DKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=68.4385382059801, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=38.3561643835616, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1790768, Length=148, Percent_Identity=31.0810810810811, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790767, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34839; Mature: 34839

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMNNDMALIERFLDTMWMERGLSENTLSSYRNDLMKLLNWLDENHYKCASISAMGLNEY
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHH
QAYLVDKQYKQTSRARMLSALRRFFQYLHREKIRGDDPTALLMSPKLPQRLPKDLSEEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCHHHH
NDLLEAPNVDDPLELRDRAMLELLYATGLRVTELVSLTMENLSLRQGVVRVTGKGDKERL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
VPMGENAVYWIQTFLDQGRSTLLGEKSSDVVFPSRRARQMTRQTFWHRIKHYAVIAGIDT
CCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCH
DKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVMNNDMALIERFLDTMWMERGLSENTLSSYRNDLMKLLNWLDENHYKCASISAMGLNEY
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHH
QAYLVDKQYKQTSRARMLSALRRFFQYLHREKIRGDDPTALLMSPKLPQRLPKDLSEEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCHHHH
NDLLEAPNVDDPLELRDRAMLELLYATGLRVTELVSLTMENLSLRQGVVRVTGKGDKERL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
VPMGENAVYWIQTFLDQGRSTLLGEKSSDVVFPSRRARQMTRQTFWHRIKHYAVIAGIDT
CCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCH
DKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHQEHHPRS
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA