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The map label for this gene is mltC [H]

Identifier: 209694125

GI number: 209694125

Start: 588313

End: 589449

Strand: Reverse

Name: mltC [H]

Synonym: VSAL_I0532

Alternate gene names: 209694125

Gene position: 589449-588313 (Counterclockwise)

Preceding gene: 209694126

Following gene: 209694124

Centisome position: 17.73

GC content: 39.84

Gene sequence:

>1137_bases
ATGAAAAAAATTATCTTAATTGTCTCTACATGTCTTTTTCTCACCAGCTGTAGCCGAGAATCCATAGAATCGACCTTTGG
TATTAATTACGACACCACCAACCGTTTTGCTAAAAATTTAGCCCCTCTTCCTGGGCAATTTACCAAAGATCTAAAAGCCC
TCGACTCTTTAATAAGCAGTTTTAATGGCAACATTGAGAAGCGTTGGGGGAAGAAAAACCTCATCACTGCAGGTAAACGT
TCTTACGTAAAATACACGGATGGGTATCTGAGTCGCTCTCAAGTCGATTTCACGTCAGGGCGAGTCACCGTCGAAACCGT
AGCAGGAACCGAGCCTAAAGCGCATTTGCGTCAAGCTATTATCACCACCCTACTCACACCAGATGACCCTGCTGGTGTTG
ATTTGTATTCAGACGCTGATGTCACCTTAGGTGGAAAACCATTTCTTTATCAGCAAGTCCTCGATCAAGATAAAAAACCG
ATTGAATGGTCATGGCGCGCAAGCCGTTACGCTGATTACCTCATTGCACATCATTTAAAACAAAAAAATATCGACTATAA
AAAAGCATATTACGTTGATATTCCTATGGTTAAAAACCACGAACAACTGCGTGAATACCAATATGCCGATATTGTTCGTA
AAGCATCTCAACGTTACGACATTCCTGAAGATTTGATTTACTCCATCATCAGAACAGAAAGTAGTTTTAATCCTTATGCC
GTAAGTTGGGCCAATGCGTATGGATTAATGCAAGTGGTACCTAAAACCGCTGGACGTGATGTTTTTAAATTGGTGAAGAA
AAAATCCGGCGATCCTACACCCGAGTATTTATTTAACCCACATAACAACATTGATACCGGCGCCGCTTACTTTCATATAT
TGAAAACACGTTACCTAAAAGACATTAGAAATCCGATTTCAAAACAATACAGCATGATTTCAGCTTATAACGGTGGTGCT
GGTGGTGTATTTACTACCTTTAGCAGTAGCAGAAGTCGTGCAATTAACGACATTAATAGTTTAAATCCGAACCAAGTCTA
TTGGGCTTTAACTAAAAAGCATAAGAATGCGGAAGCAAGACGTTACCTAGAAAAAGTAACCGCCTATAAAAAAGAGTTCA
ATTCAGGGAAGATTTAG

Upstream 100 bases:

>100_bases
TTAAATAAAGCAGCCTAGTCGCTGCTTTATTTTTATTCTTTTTTAGTTCGAGGCCATTCTGCCGTTAACCTTATTACGAG
TTCTTATCTATATAGCCTTT

Downstream 100 bases:

>100_bases
CGATAAAACAGCCTATTCGATGGATAATCAATCAAACGATCAAAAAAACGGACTATTTTGAAAAAAAAAGTTGACGGTGA
GGGCAAAAATCCGTTTAATA

Product: membrane-bound lytic murein transglycosylase C precursor

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Murein hydrolase C [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKKIILIVSTCLFLTSCSRESIESTFGINYDTTNRFAKNLAPLPGQFTKDLKALDSLISSFNGNIEKRWGKKNLITAGKR
SYVKYTDGYLSRSQVDFTSGRVTVETVAGTEPKAHLRQAIITTLLTPDDPAGVDLYSDADVTLGGKPFLYQQVLDQDKKP
IEWSWRASRYADYLIAHHLKQKNIDYKKAYYVDIPMVKNHEQLREYQYADIVRKASQRYDIPEDLIYSIIRTESSFNPYA
VSWANAYGLMQVVPKTAGRDVFKLVKKKSGDPTPEYLFNPHNNIDTGAAYFHILKTRYLKDIRNPISKQYSMISAYNGGA
GGVFTTFSSSRSRAINDINSLNPNQVYWALTKKHKNAEARRYLEKVTAYKKEFNSGKI

Sequences:

>Translated_378_residues
MKKIILIVSTCLFLTSCSRESIESTFGINYDTTNRFAKNLAPLPGQFTKDLKALDSLISSFNGNIEKRWGKKNLITAGKR
SYVKYTDGYLSRSQVDFTSGRVTVETVAGTEPKAHLRQAIITTLLTPDDPAGVDLYSDADVTLGGKPFLYQQVLDQDKKP
IEWSWRASRYADYLIAHHLKQKNIDYKKAYYVDIPMVKNHEQLREYQYADIVRKASQRYDIPEDLIYSIIRTESSFNPYA
VSWANAYGLMQVVPKTAGRDVFKLVKKKSGDPTPEYLFNPHNNIDTGAAYFHILKTRYLKDIRNPISKQYSMISAYNGGA
GGVFTTFSSSRSRAINDINSLNPNQVYWALTKKHKNAEARRYLEKVTAYKKEFNSGKI
>Mature_378_residues
MKKIILIVSTCLFLTSCSRESIESTFGINYDTTNRFAKNLAPLPGQFTKDLKALDSLISSFNGNIEKRWGKKNLITAGKR
SYVKYTDGYLSRSQVDFTSGRVTVETVAGTEPKAHLRQAIITTLLTPDDPAGVDLYSDADVTLGGKPFLYQQVLDQDKKP
IEWSWRASRYADYLIAHHLKQKNIDYKKAYYVDIPMVKNHEQLREYQYADIVRKASQRYDIPEDLIYSIIRTESSFNPYA
VSWANAYGLMQVVPKTAGRDVFKLVKKKSGDPTPEYLFNPHNNIDTGAAYFHILKTRYLKDIRNPISKQYSMISAYNGGA
GGVFTTFSSSRSRAINDINSLNPNQVYWALTKKHKNAEARRYLEKVTAYKKEFNSGKI

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082191, Length=328, Percent_Identity=50.609756097561, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI87081855, Length=163, Percent_Identity=41.1042944785276, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 43051; Mature: 43051

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIILIVSTCLFLTSCSRESIESTFGINYDTTNRFAKNLAPLPGQFTKDLKALDSLISS
CCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FNGNIEKRWGKKNLITAGKRSYVKYTDGYLSRSQVDFTSGRVTVETVAGTEPKAHLRQAI
HCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHH
ITTLLTPDDPAGVDLYSDADVTLGGKPFLYQQVLDQDKKPIEWSWRASRYADYLIAHHLK
HHHHCCCCCCCCCEEECCCCEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QKNIDYKKAYYVDIPMVKNHEQLREYQYADIVRKASQRYDIPEDLIYSIIRTESSFNPYA
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEE
VSWANAYGLMQVVPKTAGRDVFKLVKKKSGDPTPEYLFNPHNNIDTGAAYFHILKTRYLK
EEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
DIRNPISKQYSMISAYNGGAGGVFTTFSSSRSRAINDINSLNPNQVYWALTKKHKNAEAR
HHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHH
RYLEKVTAYKKEFNSGKI
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKIILIVSTCLFLTSCSRESIESTFGINYDTTNRFAKNLAPLPGQFTKDLKALDSLISS
CCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FNGNIEKRWGKKNLITAGKRSYVKYTDGYLSRSQVDFTSGRVTVETVAGTEPKAHLRQAI
HCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHH
ITTLLTPDDPAGVDLYSDADVTLGGKPFLYQQVLDQDKKPIEWSWRASRYADYLIAHHLK
HHHHCCCCCCCCCEEECCCCEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QKNIDYKKAYYVDIPMVKNHEQLREYQYADIVRKASQRYDIPEDLIYSIIRTESSFNPYA
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEE
VSWANAYGLMQVVPKTAGRDVFKLVKKKSGDPTPEYLFNPHNNIDTGAAYFHILKTRYLK
EEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
DIRNPISKQYSMISAYNGGAGGVFTTFSSSRSRAINDINSLNPNQVYWALTKKHKNAEAR
HHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHH
RYLEKVTAYKKEFNSGKI
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA