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The map label for this gene is yjcE [H]

Identifier: 209694041

GI number: 209694041

Start: 489668

End: 490945

Strand: Reverse

Name: yjcE [H]

Synonym: VSAL_I0441

Alternate gene names: 209694041

Gene position: 490945-489668 (Counterclockwise)

Preceding gene: 209694043

Following gene: 209694033

Centisome position: 14.76

GC content: 34.74

Gene sequence:

>1278_bases
ATGTCCGTCTACAATACGCTCTGTTTTCTTGCTGCTGGAGCAATGTTAATTGCATTCTTCAATAGTAAAATAGGAAAAAT
GCAAACCACGATTGCCATTACCGCAGGATCAATAATGTTATCTCTTGCGATAATAATTGCGGGCCACAATGGTTGGTTCC
ACTTAAGAGAAATAGCAACTGAAACATTAACTGAAATAAATTTTGAAGATTTCTTGTTGAAAGGAATATTAGGCTTCTTG
CTGTTTGCTGGTGGTTTAGGGATCAAACTCCCACATATGAAAGATCAAAAATGGGAAATAACTGTGTTAGCTCTCGGGGC
TACATTATTCTCAACTTTCTTTATAGGTTTTGCTCTGTGGTTTATCTGCGGATTCATAGGTATTAATTTTGACCTTATCT
ATTGTTTGTTATTTGGCGCTCTTATATCACCAACAGATCCAATAGCTGTTTTAGCTATTGTAAAAAAAATGAATGCTCCA
CAACGTATTTCAACCCAAATCGAAGGAGAATCTCTTTTTAATGACGGTTTCGGATTAGTTATATTCGTAACTTTATTTAC
GATTGCTTTCGGTAATGAAACCCCTACGATAGGGAGTGTTACTTCGTTATTCTTCCAAGAAGCCATTGGTGGCATAATTT
ATGGTTTTGTTTTAGGTCTAGTATTCCATTACCTAATAAGTTCCACGAACGACCATTCGATGGAATTATTATTAACCATT
GGTATTCCGACTGCTGGCTACGCTTTAGCTGATGTGATACATGTATCAGGCCCATTATCAATGGTTGTTGCCGGAATAAT
GATCGGAAACTGGACTCGTTTCATTGGTTTTTCAAAAGAAAGTGAAGAACACTTAGACCATTTTTGGGAATTAGTAGACG
AATTTTTAAATGGCGTTTTATTCTTATTAATAGGTATGTCTATGCTGTTATTCAAATTCCACCAAGAAGATTGGATTTTA
ATGGCTATATCTATACCGTTAGTATTAACTAGTCGATATTTAAGTGTTTATGTTTCTTATATCGGATTTAAGAGATTTAG
AACTTACAATCCATTATCCGTTAAGATCTTAACTTGGGGAGGTTTACGTGGTGGTTTAGCATTAGCGATGGCACTTGCTA
TTCCATCTGGAATTATGGTTATTCCCGACAAAAACATTGATGTAAGAGAGATTATTCTTGTAATGACTTATTCTGTCGTT
GTTTTCTCTATTTTAGTTCAAGGGTCAACTATTACTAACATGATCGAAAAAGCAAAATTATTAGAAAAAAATAAGTAA

Upstream 100 bases:

>100_bases
TTTTAACAAAATAGAAATAATATTTGATATTTATCAAATTACGCGGAAAATGATATAAGTCATAGTTTGTTACATAAAAT
ACATAATTAGAGGTTTAGTA

Downstream 100 bases:

>100_bases
TAACATTCGAAGCATAGGCTACCCTATGCTTCGAAATTTATGACACATCCTATGATATACATATCAAAAAACAATTCAAA
CACCTACTTTTAATACATTT

Product: sodium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSVYNTLCFLAAGAMLIAFFNSKIGKMQTTIAITAGSIMLSLAIIIAGHNGWFHLREIATETLTEINFEDFLLKGILGFL
LFAGGLGIKLPHMKDQKWEITVLALGATLFSTFFIGFALWFICGFIGINFDLIYCLLFGALISPTDPIAVLAIVKKMNAP
QRISTQIEGESLFNDGFGLVIFVTLFTIAFGNETPTIGSVTSLFFQEAIGGIIYGFVLGLVFHYLISSTNDHSMELLLTI
GIPTAGYALADVIHVSGPLSMVVAGIMIGNWTRFIGFSKESEEHLDHFWELVDEFLNGVLFLLIGMSMLLFKFHQEDWIL
MAISIPLVLTSRYLSVYVSYIGFKRFRTYNPLSVKILTWGGLRGGLALAMALAIPSGIMVIPDKNIDVREIILVMTYSVV
VFSILVQGSTITNMIEKAKLLEKNK

Sequences:

>Translated_425_residues
MSVYNTLCFLAAGAMLIAFFNSKIGKMQTTIAITAGSIMLSLAIIIAGHNGWFHLREIATETLTEINFEDFLLKGILGFL
LFAGGLGIKLPHMKDQKWEITVLALGATLFSTFFIGFALWFICGFIGINFDLIYCLLFGALISPTDPIAVLAIVKKMNAP
QRISTQIEGESLFNDGFGLVIFVTLFTIAFGNETPTIGSVTSLFFQEAIGGIIYGFVLGLVFHYLISSTNDHSMELLLTI
GIPTAGYALADVIHVSGPLSMVVAGIMIGNWTRFIGFSKESEEHLDHFWELVDEFLNGVLFLLIGMSMLLFKFHQEDWIL
MAISIPLVLTSRYLSVYVSYIGFKRFRTYNPLSVKILTWGGLRGGLALAMALAIPSGIMVIPDKNIDVREIILVMTYSVV
VFSILVQGSTITNMIEKAKLLEKNK
>Mature_424_residues
SVYNTLCFLAAGAMLIAFFNSKIGKMQTTIAITAGSIMLSLAIIIAGHNGWFHLREIATETLTEINFEDFLLKGILGFLL
FAGGLGIKLPHMKDQKWEITVLALGATLFSTFFIGFALWFICGFIGINFDLIYCLLFGALISPTDPIAVLAIVKKMNAPQ
RISTQIEGESLFNDGFGLVIFVTLFTIAFGNETPTIGSVTSLFFQEAIGGIIYGFVLGLVFHYLISSTNDHSMELLLTIG
IPTAGYALADVIHVSGPLSMVVAGIMIGNWTRFIGFSKESEEHLDHFWELVDEFLNGVLFLLIGMSMLLFKFHQEDWILM
AISIPLVLTSRYLSVYVSYIGFKRFRTYNPLSVKILTWGGLRGGLALAMALAIPSGIMVIPDKNIDVREIILVMTYSVVV
FSILVQGSTITNMIEKAKLLEKNK

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=335, Percent_Identity=25.6716417910448, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI15529998, Length=335, Percent_Identity=27.4626865671642, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI41872703, Length=343, Percent_Identity=25.6559766763848, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI110227626, Length=374, Percent_Identity=22.7272727272727, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI294997330, Length=374, Percent_Identity=22.7272727272727, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI5454070, Length=357, Percent_Identity=22.96918767507, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27777632, Length=337, Percent_Identity=23.4421364985163, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4759144, Length=344, Percent_Identity=25.8720930232558, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI194239733, Length=397, Percent_Identity=24.1813602015113, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790501, Length=320, Percent_Identity=27.8125, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71999819, Length=401, Percent_Identity=22.9426433915212, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71999817, Length=401, Percent_Identity=22.9426433915212, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71999821, Length=401, Percent_Identity=22.9426433915212, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71990924, Length=364, Percent_Identity=24.7252747252747, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71990932, Length=364, Percent_Identity=24.7252747252747, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980847, Length=359, Percent_Identity=24.7910863509749, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71987535, Length=341, Percent_Identity=23.7536656891496, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987537, Length=341, Percent_Identity=23.7536656891496, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71992107, Length=300, Percent_Identity=25.6666666666667, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71992101, Length=300, Percent_Identity=25.6666666666667, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25150332, Length=327, Percent_Identity=23.8532110091743, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71993582, Length=329, Percent_Identity=24.0121580547112, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993590, Length=329, Percent_Identity=24.0121580547112, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147678, Length=305, Percent_Identity=23.2786885245902, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=304, Percent_Identity=24.0131578947368, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221510740, Length=346, Percent_Identity=26.0115606936416, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585580, Length=346, Percent_Identity=26.0115606936416, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585578, Length=346, Percent_Identity=26.0115606936416, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221510734, Length=352, Percent_Identity=25.5681818181818, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221510738, Length=351, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360447, Length=395, Percent_Identity=23.0379746835443, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221473212, Length=348, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364513, Length=348, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221473222, Length=348, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221473215, Length=348, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221510736, Length=347, Percent_Identity=25.6484149855908, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221510732, Length=347, Percent_Identity=25.6484149855908, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46853; Mature: 46722

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYNTLCFLAAGAMLIAFFNSKIGKMQTTIAITAGSIMLSLAIIIAGHNGWFHLREIAT
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHEECCCCCHHHHHHHH
ETLTEINFEDFLLKGILGFLLFAGGLGIKLPHMKDQKWEITVLALGATLFSTFFIGFALW
HHHHHCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
FICGFIGINFDLIYCLLFGALISPTDPIAVLAIVKKMNAPQRISTQIEGESLFNDGFGLV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCHHH
IFVTLFTIAFGNETPTIGSVTSLFFQEAIGGIIYGFVLGLVFHYLISSTNDHSMELLLTI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GIPTAGYALADVIHVSGPLSMVVAGIMIGNWTRFIGFSKESEEHLDHFWELVDEFLNGVL
CCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FLLIGMSMLLFKFHQEDWILMAISIPLVLTSRYLSVYVSYIGFKRFRTYNPLSVKILTWG
HHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GLRGGLALAMALAIPSGIMVIPDKNIDVREIILVMTYSVVVFSILVQGSTITNMIEKAKL
CCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEKNK
HHCCC
>Mature Secondary Structure 
SVYNTLCFLAAGAMLIAFFNSKIGKMQTTIAITAGSIMLSLAIIIAGHNGWFHLREIAT
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHEECCCCCHHHHHHHH
ETLTEINFEDFLLKGILGFLLFAGGLGIKLPHMKDQKWEITVLALGATLFSTFFIGFALW
HHHHHCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
FICGFIGINFDLIYCLLFGALISPTDPIAVLAIVKKMNAPQRISTQIEGESLFNDGFGLV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCHHH
IFVTLFTIAFGNETPTIGSVTSLFFQEAIGGIIYGFVLGLVFHYLISSTNDHSMELLLTI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GIPTAGYALADVIHVSGPLSMVVAGIMIGNWTRFIGFSKESEEHLDHFWELVDEFLNGVL
CCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FLLIGMSMLLFKFHQEDWILMAISIPLVLTSRYLSVYVSYIGFKRFRTYNPLSVKILTWG
HHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GLRGGLALAMALAIPSGIMVIPDKNIDVREIILVMTYSVVVFSILVQGSTITNMIEKAKL
CCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEKNK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]