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The map label for this gene is betA [H]

Identifier: 209552169

GI number: 209552169

Start: 277896

End: 279560

Strand: Reverse

Name: betA [H]

Synonym: Rleg2_6326

Alternate gene names: 209552169

Gene position: 279560-277896 (Counterclockwise)

Preceding gene: 209552170

Following gene: 209552168

Centisome position: 90.55

GC content: 59.16

Gene sequence:

>1665_bases
ATGGATCGGGAGTTCGATTTCATCGTAGTTGGGGGTGGATCTGCTGGCTGCGCGCTCGCGTCGCGGCTGAGCGAGAATGC
GGCTTCGACTGTTCTTCTCATTGAGGCTGGTCCGGACGCAAATCCCTGGCAGGTGAGAATGCCTCTGGCGGTTGATGCGC
TTCTCACGTCCACGAAATACAATTGGGCATTTCAGTCCGCGGCTGAGCCAGGCCTCGGCGGGCGCGTCATTGAACATCCG
CGTGGTAGAGTGCTGGGCGGTTCTTCTGCGATCAACGGCATGGTCTACACCAGGGGGAATCCGCAGGACTACGACGAGTG
GCGTGATGAGCACGGTTGTCGCGGCTGGGGCTACGCCGACGTGCTTCCCTATTTCATTCGAATGGAGTCGACCGAAAGCG
GTGACAGCCGTTATCGTGGCAGAAAGGGCCCGCTCAAAGTCACGAAGCCGCGGACGAAGAATCCCCTGAATCTTGCGTTC
CTGGCAGCGGGCGAGGAATTGGGTTATCCGATCACCGACGACTCCAATGGCCCCCAGCACGAGGGCTTTGCCATTGCCGA
GCAGACCATCGTCAACGGCCAGCGAAACTCCACTGCCGCGGCGTACCTTTCTCCAGCCGTTCGTTCCCGGCCGAACCTGA
CCATCGCTTCCAAGACGGTCGTGGAAAGAATCCTGTTCGAAGGCCGTCGGGCGTCGGGCGTGCGGTGTCAGTCTTCTGAA
AAAGCCGAGGTCTTCAAGTCTCGCCGCGAGATCATACTGTCGGCGGGCGGCGTCGGCAGCCCGCACATTCTGAAACTCTC
GGGTATCGGACCGGCCGCGGAACTGCAGGAGCACGGTATCGCGATCGTACACGACCTGAAGGGCGTCGGGGCAAACCTCC
AGGACCATCTCGATCTCCCGATCCAGTTCACCTGCAAACAACCGGTAAGTCTGAAGCGAAGCACCGAATGGCCCCGCAAA
GCCTTCGTCGGATTGAACTGGTTCCTTTTGAAGGGCGGCGTTGCGGCAAGCAACCAGTTCGAAGTGACGGCCTACATCCG
CAGCCGCGCAGGGATCTCGAAACCCAACCTGAAATTCGAGTTCTTCCCGCTGAGCATTTCGCACGATAATTTCAAACCCT
ATCCCCAGGAGGCGTTCCAAATCCACTGCACTGTGGAGACGTCATACGCCCGAGGGAACCTGCTCCTAAAGTCATCCAAT
CCAAACGAAGCGCCGTCGCTGAATTTCAACTATCTGAGCGACGAACGGGACATGCAAACCTTCCGGGAGGGCGTTGGGTT
GGTGCGCGAATTGGTTGCTTCGCGGGCATTTGATCCGTACCGCGGCACCGAAATGGACCCCGGCGAAGCGGTGAAAAGCA
GGGAAGCGCTCGACGAGTGGATCCGGCGCAGAGCTACGACGGCGTTTCATATTTCCGGCACCTGCGCGATGGGGCGACAG
GACGACCCAAATGCGGTCATCGGCCCAGACCTGAAGGTTCATGGAGTGGAAGGTTTGCGTGTCGCGGATGCTTCTATCAT
GCCGGTCGTCGTTACTTCGAACCTAAATGCATCGGCAATCATGATAGGCGAGCGCGCCGCTGACTTCACGCTTGGACGTC
CGCAACTCAGCCCGTCGAACGAGCCTTACTGGGTTAACCCCAACTGGCAAACCAGCCAGCGTTGA

Upstream 100 bases:

>100_bases
CTCTCGATAGACTAAATGGACAAATAAATATACGCACGAGTTTGTTATGCGGCCCGCTGCGTTTGTGGCGGCGAATTCTT
CTTTTCGGGATGGGAGAGGC

Downstream 100 bases:

>100_bases
TATCGCTCAACGTGAATTCACAGCAGCGCCGCCGGCGCGGCGAGCACAGGAGATCGGCAATGGATACGAAACAAGCTGTT
CCGGGGGAAATGCGGGCTGT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MDREFDFIVVGGGSAGCALASRLSENAASTVLLIEAGPDANPWQVRMPLAVDALLTSTKYNWAFQSAAEPGLGGRVIEHP
RGRVLGGSSAINGMVYTRGNPQDYDEWRDEHGCRGWGYADVLPYFIRMESTESGDSRYRGRKGPLKVTKPRTKNPLNLAF
LAAGEELGYPITDDSNGPQHEGFAIAEQTIVNGQRNSTAAAYLSPAVRSRPNLTIASKTVVERILFEGRRASGVRCQSSE
KAEVFKSRREIILSAGGVGSPHILKLSGIGPAAELQEHGIAIVHDLKGVGANLQDHLDLPIQFTCKQPVSLKRSTEWPRK
AFVGLNWFLLKGGVAASNQFEVTAYIRSRAGISKPNLKFEFFPLSISHDNFKPYPQEAFQIHCTVETSYARGNLLLKSSN
PNEAPSLNFNYLSDERDMQTFREGVGLVRELVASRAFDPYRGTEMDPGEAVKSREALDEWIRRRATTAFHISGTCAMGRQ
DDPNAVIGPDLKVHGVEGLRVADASIMPVVVTSNLNASAIMIGERAADFTLGRPQLSPSNEPYWVNPNWQTSQR

Sequences:

>Translated_554_residues
MDREFDFIVVGGGSAGCALASRLSENAASTVLLIEAGPDANPWQVRMPLAVDALLTSTKYNWAFQSAAEPGLGGRVIEHP
RGRVLGGSSAINGMVYTRGNPQDYDEWRDEHGCRGWGYADVLPYFIRMESTESGDSRYRGRKGPLKVTKPRTKNPLNLAF
LAAGEELGYPITDDSNGPQHEGFAIAEQTIVNGQRNSTAAAYLSPAVRSRPNLTIASKTVVERILFEGRRASGVRCQSSE
KAEVFKSRREIILSAGGVGSPHILKLSGIGPAAELQEHGIAIVHDLKGVGANLQDHLDLPIQFTCKQPVSLKRSTEWPRK
AFVGLNWFLLKGGVAASNQFEVTAYIRSRAGISKPNLKFEFFPLSISHDNFKPYPQEAFQIHCTVETSYARGNLLLKSSN
PNEAPSLNFNYLSDERDMQTFREGVGLVRELVASRAFDPYRGTEMDPGEAVKSREALDEWIRRRATTAFHISGTCAMGRQ
DDPNAVIGPDLKVHGVEGLRVADASIMPVVVTSNLNASAIMIGERAADFTLGRPQLSPSNEPYWVNPNWQTSQR
>Mature_554_residues
MDREFDFIVVGGGSAGCALASRLSENAASTVLLIEAGPDANPWQVRMPLAVDALLTSTKYNWAFQSAAEPGLGGRVIEHP
RGRVLGGSSAINGMVYTRGNPQDYDEWRDEHGCRGWGYADVLPYFIRMESTESGDSRYRGRKGPLKVTKPRTKNPLNLAF
LAAGEELGYPITDDSNGPQHEGFAIAEQTIVNGQRNSTAAAYLSPAVRSRPNLTIASKTVVERILFEGRRASGVRCQSSE
KAEVFKSRREIILSAGGVGSPHILKLSGIGPAAELQEHGIAIVHDLKGVGANLQDHLDLPIQFTCKQPVSLKRSTEWPRK
AFVGLNWFLLKGGVAASNQFEVTAYIRSRAGISKPNLKFEFFPLSISHDNFKPYPQEAFQIHCTVETSYARGNLLLKSSN
PNEAPSLNFNYLSDERDMQTFREGVGLVRELVASRAFDPYRGTEMDPGEAVKSREALDEWIRRRATTAFHISGTCAMGRQ
DDPNAVIGPDLKVHGVEGLRVADASIMPVVVTSNLNASAIMIGERAADFTLGRPQLSPSNEPYWVNPNWQTSQR

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=558, Percent_Identity=44.6236559139785, Blast_Score=484, Evalue=1e-137,
Organism=Escherichia coli, GI1786503, Length=548, Percent_Identity=43.4306569343066, Blast_Score=456, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17532301, Length=554, Percent_Identity=39.7111913357401, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24642042, Length=591, Percent_Identity=34.8561759729272, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24650267, Length=573, Percent_Identity=35.7766143106457, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24642048, Length=586, Percent_Identity=35.6655290102389, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI45551458, Length=567, Percent_Identity=34.7442680776014, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI45549471, Length=567, Percent_Identity=34.7442680776014, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI17137792, Length=553, Percent_Identity=36.7088607594937, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642059, Length=575, Percent_Identity=35.304347826087, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI18859995, Length=564, Percent_Identity=34.5744680851064, Blast_Score=270, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24642051, Length=567, Percent_Identity=32.2751322751323, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24642039, Length=565, Percent_Identity=33.6283185840708, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24642055, Length=572, Percent_Identity=34.4405594405594, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24642037, Length=582, Percent_Identity=34.192439862543, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24642035, Length=570, Percent_Identity=34.0350877192982, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI18859993, Length=574, Percent_Identity=32.5783972125435, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24645930, Length=587, Percent_Identity=27.5979557069847, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24642057, Length=584, Percent_Identity=29.7945205479452, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 60686; Mature: 60686

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00623 GMC_OXRED_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREFDFIVVGGGSAGCALASRLSENAASTVLLIEAGPDANPWQVRMPLAVDALLTSTKY
CCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCEEEEHHHHCCCC
NWAFQSAAEPGLGGRVIEHPRGRVLGGSSAINGMVYTRGNPQDYDEWRDEHGCRGWGYAD
CEEECCCCCCCCCCCEEECCCCCEECCCHHHCCEEEECCCCCCHHHHHHHCCCCCCCHHH
VLPYFIRMESTESGDSRYRGRKGPLKVTKPRTKNPLNLAFLAAGEELGYPITDDSNGPQH
HHEEHEEEECCCCCCHHCCCCCCCEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCCCCC
EGFAIAEQTIVNGQRNSTAAAYLSPAVRSRPNLTIASKTVVERILFEGRRASGVRCQSSE
CCEEEEHHHHHCCCCCCCHHHEECHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCC
KAEVFKSRREIILSAGGVGSPHILKLSGIGPAAELQEHGIAIVHDLKGVGANLQDHLDLP
HHHHHHHHHHEEEECCCCCCCEEEEEECCCCHHHHHHCCEEEEEECCCCCCCHHHCCCCC
IQFTCKQPVSLKRSTEWPRKAFVGLNWFLLKGGVAASNQFEVTAYIRSRAGISKPNLKFE
EEEECCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEE
FFPLSISHDNFKPYPQEAFQIHCTVETSYARGNLLLKSSNPNEAPSLNFNYLSDERDMQT
EEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCHHHHHH
FREGVGLVRELVASRAFDPYRGTEMDPGEAVKSREALDEWIRRRATTAFHISGTCAMGRQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECEEECCCC
DDPNAVIGPDLKVHGVEGLRVADASIMPVVVTSNLNASAIMIGERAADFTLGRPQLSPSN
CCCCEEECCCEEEECCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCC
EPYWVNPNWQTSQR
CCEEECCCCCCCCC
>Mature Secondary Structure
MDREFDFIVVGGGSAGCALASRLSENAASTVLLIEAGPDANPWQVRMPLAVDALLTSTKY
CCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCEEEEHHHHCCCC
NWAFQSAAEPGLGGRVIEHPRGRVLGGSSAINGMVYTRGNPQDYDEWRDEHGCRGWGYAD
CEEECCCCCCCCCCCEEECCCCCEECCCHHHCCEEEECCCCCCHHHHHHHCCCCCCCHHH
VLPYFIRMESTESGDSRYRGRKGPLKVTKPRTKNPLNLAFLAAGEELGYPITDDSNGPQH
HHEEHEEEECCCCCCHHCCCCCCCEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCCCCC
EGFAIAEQTIVNGQRNSTAAAYLSPAVRSRPNLTIASKTVVERILFEGRRASGVRCQSSE
CCEEEEHHHHHCCCCCCCHHHEECHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCC
KAEVFKSRREIILSAGGVGSPHILKLSGIGPAAELQEHGIAIVHDLKGVGANLQDHLDLP
HHHHHHHHHHEEEECCCCCCCEEEEEECCCCHHHHHHCCEEEEEECCCCCCCHHHCCCCC
IQFTCKQPVSLKRSTEWPRKAFVGLNWFLLKGGVAASNQFEVTAYIRSRAGISKPNLKFE
EEEECCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEE
FFPLSISHDNFKPYPQEAFQIHCTVETSYARGNLLLKSSNPNEAPSLNFNYLSDERDMQT
EEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCHHHHHH
FREGVGLVRELVASRAFDPYRGTEMDPGEAVKSREALDEWIRRRATTAFHISGTCAMGRQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECEEECCCC
DDPNAVIGPDLKVHGVEGLRVADASIMPVVVTSNLNASAIMIGERAADFTLGRPQLSPSN
CCCCEEECCCEEEECCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCC
EPYWVNPNWQTSQR
CCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA