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The map label for this gene is aroE [H]

Identifier: 209552112

GI number: 209552112

Start: 206691

End: 207530

Strand: Reverse

Name: aroE [H]

Synonym: Rleg2_6263

Alternate gene names: 209552112

Gene position: 207530-206691 (Counterclockwise)

Preceding gene: 209552115

Following gene: 209552108

Centisome position: 67.22

GC content: 55.6

Gene sequence:

>840_bases
ATGTCGACATTATGTCGAGCGCAAATTAAGAAAGACACGGCGTTGGAAATCACAGGCAAGACAAAGATCTTCTACATGAT
CGCACATCCGATTGATCACGTTCGTTCGCCGGAAGTATTCAACCCCTGGTTCAGAGAAAACGCCGTGGACGCGGTGATGA
TCCCGGTTCACTATCGCCCGGACGACTTCGAGGCCGTTTGGGACAGTTTGCGACACACAGCAAACCTAGGCGGCTTCATG
GTAAGCGTGCCGCACAAGGAGAAGGCCTATCAACTTTGCGACGAACATCACGAAACGGCAGAGCTTGTCACTGCGGTGAA
TGCCGTCAGGCGTGACGAGCATGGGCGCCTGACAGGAGCAAATTTCGATGGTCCCGGCTTTATGGCAGGTGTTCTCGCTG
GCCCTCATGAGGTCTCGGGGAAATCTGTCCTATTGGTAGGCGCCGGCGGAGCAGGAGCCTCGATCGGCTTCCAGGTCGCA
AAGGCAGGAGCTGAACGGATCACCATCAGCGATCTCAACACCTCACGCGCAACGGAGCTTGCGGATAGAATTCTTGCACG
CTTCCCGAAGGTGAATGTGCGACTGGGGAGCATTGACCCGAAGGGGCACGACATCGTCGTCAATGCGACGCCGTGCGGCC
TCCATCCAGAAACAGATTCGATTCCCGTTGAGCTCGACAATATCTCATCCGACATGATTATTGCGGACATCATCATGAAA
CCACGCGTCACGCCATTGCTTGCAGCGGCGAAGGAGATCGGGTGCGACGTCCGCTATGGCGGCGGCATGCTCGATATGCA
GCGCGACCTAACGCTGAAATTCTACGGGTTGAAGATCTGA

Upstream 100 bases:

>100_bases
GCATCTCAACCTTCAAAATAGGCATGACCGTTCCCTGCTCTACGTTTTTCTGATCGAACCGTCTTTCGGCTTGCCGTCGG
TCCTGACTTTCGTTTATCAT

Downstream 100 bases:

>100_bases
AGCGAAAGGTGCCGGAACGCCAATTCTCGCCCCGGCATCTGGTTCAGGCTGAGTTGCGTAAGCTTGATATGCCGAGCCTA
CCAGAAAGCGGCAATCGACA

Product: shikimate dehydrogenase substrate binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSTLCRAQIKKDTALEITGKTKIFYMIAHPIDHVRSPEVFNPWFRENAVDAVMIPVHYRPDDFEAVWDSLRHTANLGGFM
VSVPHKEKAYQLCDEHHETAELVTAVNAVRRDEHGRLTGANFDGPGFMAGVLAGPHEVSGKSVLLVGAGGAGASIGFQVA
KAGAERITISDLNTSRATELADRILARFPKVNVRLGSIDPKGHDIVVNATPCGLHPETDSIPVELDNISSDMIIADIIMK
PRVTPLLAAAKEIGCDVRYGGGMLDMQRDLTLKFYGLKI

Sequences:

>Translated_279_residues
MSTLCRAQIKKDTALEITGKTKIFYMIAHPIDHVRSPEVFNPWFRENAVDAVMIPVHYRPDDFEAVWDSLRHTANLGGFM
VSVPHKEKAYQLCDEHHETAELVTAVNAVRRDEHGRLTGANFDGPGFMAGVLAGPHEVSGKSVLLVGAGGAGASIGFQVA
KAGAERITISDLNTSRATELADRILARFPKVNVRLGSIDPKGHDIVVNATPCGLHPETDSIPVELDNISSDMIIADIIMK
PRVTPLLAAAKEIGCDVRYGGGMLDMQRDLTLKFYGLKI
>Mature_278_residues
STLCRAQIKKDTALEITGKTKIFYMIAHPIDHVRSPEVFNPWFRENAVDAVMIPVHYRPDDFEAVWDSLRHTANLGGFMV
SVPHKEKAYQLCDEHHETAELVTAVNAVRRDEHGRLTGANFDGPGFMAGVLAGPHEVSGKSVLLVGAGGAGASIGFQVAK
AGAERITISDLNTSRATELADRILARFPKVNVRLGSIDPKGHDIVVNATPCGLHPETDSIPVELDNISSDMIIADIIMKP
RVTPLLAAAKEIGCDVRYGGGMLDMQRDLTLKFYGLKI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=28.3582089552239, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789675, Length=253, Percent_Identity=29.6442687747036, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30349; Mature: 30218

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLCRAQIKKDTALEITGKTKIFYMIAHPIDHVRSPEVFNPWFRENAVDAVMIPVHYRP
CCCHHHHHHCCCCEEEEECCEEEEEEEECCHHHCCCCCCCCCHHHCCCCCEEEEEEEECC
DDFEAVWDSLRHTANLGGFMVSVPHKEKAYQLCDEHHETAELVTAVNAVRRDEHGRLTGA
CHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
NFDGPGFMAGVLAGPHEVSGKSVLLVGAGGAGASIGFQVAKAGAERITISDLNTSRATEL
CCCCCCCEEHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHH
ADRILARFPKVNVRLGSIDPKGHDIVVNATPCGLHPETDSIPVELDNISSDMIIADIIMK
HHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCEEEEEHHHC
PRVTPLLAAAKEIGCDVRYGGGMLDMQRDLTLKFYGLKI
CCCCHHHHHHHHHCCEEEECCCEEEECCCCEEEEEEECC
>Mature Secondary Structure 
STLCRAQIKKDTALEITGKTKIFYMIAHPIDHVRSPEVFNPWFRENAVDAVMIPVHYRP
CCHHHHHHCCCCEEEEECCEEEEEEEECCHHHCCCCCCCCCHHHCCCCCEEEEEEEECC
DDFEAVWDSLRHTANLGGFMVSVPHKEKAYQLCDEHHETAELVTAVNAVRRDEHGRLTGA
CHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
NFDGPGFMAGVLAGPHEVSGKSVLLVGAGGAGASIGFQVAKAGAERITISDLNTSRATEL
CCCCCCCEEHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHH
ADRILARFPKVNVRLGSIDPKGHDIVVNATPCGLHPETDSIPVELDNISSDMIIADIIMK
HHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCEEEEEHHHC
PRVTPLLAAAKEIGCDVRYGGGMLDMQRDLTLKFYGLKI
CCCCHHHHHHHHHCCEEEECCCEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]