BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence.
Accession	NC_011370
Length	308,747

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The map label for this gene is fabG [H]

Identifier: 209551990

GI number: 209551990

Start: 63636

End: 64406

Strand: Reverse

Name: fabG [H]

Synonym: Rleg2_6130

Alternate gene names: 209551990

Gene position: 64406-63636 (Counterclockwise)

Preceding gene: 209551991

Following gene: 209551989

Centisome position: 20.86

GC content: 62.26

Gene sequence:

>771_bases
ATGCAAATTAAAGGGAACCTTTGCGCCGTGACTGGCGCGGCCTCTGGTCTGGGACGGGCGACAGCGAAGGCGCTTCATGA
CGCAGGAGCGGCAGTTCTGCTCCTGGACCTTAATAAGGACCGGCTTGAGGAGCTTCAGGCCGAGTTGGCGCCCGGCACCA
CGCTGGCCGTGGCGGTTGATGTAAGGGATCCCGGAGACATCGAACGATCATTCGACGATGCGATCGCGATGTTCGGACCG
CTACGCGCCGTCGTAAACTGCGCCGGCATCGCCTCGTCCGCCAAAATCGTGTCGCGAGGCGAGCCGCACGATTTTGATCT
CTGGCGCCGGGTCATCGACATCAATCTGAACGGAAGCTTCAATGTCATGAGGCTGGCGGCTGCCCGAATGGTGAAGAACG
AACCCATCGGCGAAGCCGGGGAGCGGGGAGTTATCGTCAACACCGCATCGGTCGCAGCCGAGGACGGACAAAAAGGCCAG
GCTGCGTACGCCGCTAGCAAGGCGGGCATCGCTGCTCTCTCGCTTCCGGTGGCCCGCGATCTTGCGGAGCACGCGATACG
CTGCGTCGCGGTCGCGCCTGGACTGTTCGGCACCGAACTATTCGACCACATCCCTGAGAAGGGTATCGAGGCCCTGAAGC
GCGCGCTTCTCTACCCCGCGAGGATGGGACTGCCCAGCGAATTTGCCGGCCTGGTAAGGCATATTGTCGAGAACCCATAT
CTGAACGGGTCTCTCATTCGGCTGGATGGCGGCGCCCGCCTTCCTGCCTGA

Upstream 100 bases:

>100_bases
AGCCTGCCTAAGACGCCGTCCGGAAAGATCCAGCGCTTCGTGGTGCGGCAGCAGGCAAGGGACGGAACGCTTGCGACGTT
GAGCATTAGGGGAGCAGTCG

Downstream 100 bases:

>100_bases
CGCCCGGAAAAGGAAAAACATATGACCGAACCTGCGATCCTGTTCGACGTTGACCGGACGGCAAAACGCCTCAACGAGAT
ATCCGAGCGAAGCGGCAAGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQIKGNLCAVTGAASGLGRATAKALHDAGAAVLLLDLNKDRLEELQAELAPGTTLAVAVDVRDPGDIERSFDDAIAMFGP
LRAVVNCAGIASSAKIVSRGEPHDFDLWRRVIDINLNGSFNVMRLAAARMVKNEPIGEAGERGVIVNTASVAAEDGQKGQ
AAYAASKAGIAALSLPVARDLAEHAIRCVAVAPGLFGTELFDHIPEKGIEALKRALLYPARMGLPSEFAGLVRHIVENPY
LNGSLIRLDGGARLPA

Sequences:

>Translated_256_residues
MQIKGNLCAVTGAASGLGRATAKALHDAGAAVLLLDLNKDRLEELQAELAPGTTLAVAVDVRDPGDIERSFDDAIAMFGP
LRAVVNCAGIASSAKIVSRGEPHDFDLWRRVIDINLNGSFNVMRLAAARMVKNEPIGEAGERGVIVNTASVAAEDGQKGQ
AAYAASKAGIAALSLPVARDLAEHAIRCVAVAPGLFGTELFDHIPEKGIEALKRALLYPARMGLPSEFAGLVRHIVENPY
LNGSLIRLDGGARLPA
>Mature_256_residues
MQIKGNLCAVTGAASGLGRATAKALHDAGAAVLLLDLNKDRLEELQAELAPGTTLAVAVDVRDPGDIERSFDDAIAMFGP
LRAVVNCAGIASSAKIVSRGEPHDFDLWRRVIDINLNGSFNVMRLAAARMVKNEPIGEAGERGVIVNTASVAAEDGQKGQ
AAYAASKAGIAALSLPVARDLAEHAIRCVAVAPGLFGTELFDHIPEKGIEALKRALLYPARMGLPSEFAGLVRHIVENPY
LNGSLIRLDGGARLPA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=47.6377952755905, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=46.0629921259843, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=32.0610687022901, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.1204819277108, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI31542939, Length=262, Percent_Identity=29.0076335877863, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=32.0675105485232, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=31.4606741573034, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI59889578, Length=238, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=30.2325581395349, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=29.1044776119403, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082160, Length=268, Percent_Identity=26.1194029850746, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.5140562248996, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.3253012048193, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=27.4131274131274, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787820, Length=203, Percent_Identity=29.5566502463054, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=44.7058823529412, Blast_Score=196, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=30.5555555555556, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=27.843137254902, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=28, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=29.3893129770992, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=24.8148148148148, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=26.2962962962963, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=28.6821705426357, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.4725274725275, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=26.7657992565056, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=25.0922509225092, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=213, Percent_Identity=27.6995305164319, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=24.7148288973384, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=25.830258302583, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=26.2172284644195, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=27.7372262773723, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=216, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=216, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=211, Percent_Identity=24.6445497630332, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=207, Percent_Identity=29.951690821256, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=28.2828282828283, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=47.6377952755905, Blast_Score=217, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=31.6205533596838, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24665243, Length=214, Percent_Identity=31.7757009345794, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221331218, Length=214, Percent_Identity=31.7757009345794, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=203, Percent_Identity=30.0492610837438, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221331216, Length=215, Percent_Identity=31.6279069767442, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24665247, Length=215, Percent_Identity=31.6279069767442, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=201, Percent_Identity=26.3681592039801, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26803; Mature: 26803

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKGNLCAVTGAASGLGRATAKALHDAGAAVLLLDLNKDRLEELQAELAPGTTLAVAVD
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEE
VRDPGDIERSFDDAIAMFGPLRAVVNCAGIASSAKIVSRGEPHDFDLWRRVIDINLNGSF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHEEEEECCCCC
NVMRLAAARMVKNEPIGEAGERGVIVNTASVAAEDGQKGQAAYAASKAGIAALSLPVARD
HHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHH
LAEHAIRCVAVAPGLFGTELFDHIPEKGIEALKRALLYPARMGLPSEFAGLVRHIVENPY
HHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LNGSLIRLDGGARLPA
CCCEEEEECCCCCCCC
>Mature Secondary Structure
MQIKGNLCAVTGAASGLGRATAKALHDAGAAVLLLDLNKDRLEELQAELAPGTTLAVAVD
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEE
VRDPGDIERSFDDAIAMFGPLRAVVNCAGIASSAKIVSRGEPHDFDLWRRVIDINLNGSF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHEEEEECCCCC
NVMRLAAARMVKNEPIGEAGERGVIVNTASVAAEDGQKGQAAYAASKAGIAALSLPVARD
HHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHH
LAEHAIRCVAVAPGLFGTELFDHIPEKGIEALKRALLYPARMGLPSEFAGLVRHIVENPY
HHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LNGSLIRLDGGARLPA
CCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]