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The map label for this gene is cya3 [H]

Identifier: 209550722

GI number: 209550722

Start: 3218996

End: 3220792

Strand: Direct

Name: cya3 [H]

Synonym: Rleg2_3146

Alternate gene names: 209550722

Gene position: 3218996-3220792 (Clockwise)

Preceding gene: 209550721

Following gene: 209550724

Centisome position: 70.94

GC content: 63.11

Gene sequence:

>1797_bases
GTGACGCGAAAACTGGCGGCGATCCTGGTCGCCGATGTAGTCGGCTACAGCCGCCTCGCCGGTGCGGACGAGGATCGCAT
CCTGGCGCGGCTGAGAACCTTGCGCAGCGATCTGGTCGATCCCACCATCGCCGTGCACAATGGCCGTATCGTCAAGCGCA
CCGGCGATGGAAGCCTCATCGAGTTTCGCAGCGTCGTCGACGCCGTGCGCTGCGCGATCGAGGTGCAGACTGCCATGGTC
GAGCGCAATATCGGCGTGCCTCCCGAGCATCGCATCGAGTTCCGGGTCGGCATCCATCTGGGCGACGTCGTCGAGGAGAA
CGACGGCGACCTGATGGGCGACGGCGTCAACATCGCCGCGCGGTTGGAGGGAGTTGCTGAGCCTGGCGCCATCTGCCTCT
CCGAGGATGCCTACCGCCAGGTAAGAGCGCGACTTGAATGTGCCGTGACCGATCTCGGCAAAGTTCCCCTCAAAAATATC
GCGGAGCCGATGCGGGTCTATTTGCTTCAGGTCGGAACCGCCTCGCAGCCGGTGTCGGCACCGCAACCGGGAGAGCAGCC
GGCGCCGAGACGGCCTACGGCTGCAGCCGTTCCCGACAAGCCCTCCATCGCCGTACTGGCCTTCAACAATATGAGCGGCG
ACGCCGAACAGGAATATTTCTCCGACGGGATCAGCGAGGACATCATCACCGACCTCTCCAAGCTGTCCGAATTGCACGTG
ATCGCCCGCAACTCATCCTTCGTCTACAAGAATGTAACAGCCTCGGTACCTGAGATGGCTAAGGCGCTCGGCGTCCGTTA
TGTCCTCGAAGGCAGTGTGCGCAAGGCCGGCAATCGCGTGCGTGTGACGGCCCAATTGATCGACGCCAGCAATGGCGGAC
ATATCTGGGCCAGCCGCTACGATCGCGATCTCACCGACATTTTTGCGGTTCAGGATGAACTGACCCAGGAGATCGTCACA
GCGCTGAAGCTCAATCTCACCCATGGCGACCAGGACCGCCTGGCCCAGGGGCGCGCCGTGGATGTCAGCGCTTACGAGCT
GTTGTTGCGTGGCCGTGAGCAGGCGTCAGCTCATAACCGAACCGGAAATAGAGCCGCCCGCAGCCTGGCGGCAGACGCTC
TCGCCGTCGACCCGGACTATGCGGCGGCCCGGGCCCTCATTTCGTTCACGCATGTGCTCGACTACGTCAACGCCTGGAGC
GACGATCCGGAGGGCTCGCTGCGGACCGGGCTGGATCTCGCGCAGCAGGCAGTTGATATGGCCGAGGAACAGCCCAACAG
CCACTTCGCACTGGGCATGGCCTGCATGTGGAACCACGAGCTCGACCGGGCGCGGGCAGAAGTGCTGCGCGGCCTGGCGC
TGTCGCCCAACTCGGCCGAACTCCTGACACTGATGGCGCATATCCAGATATTCGCCGGCGATCCCGCAGGCGCCTTGGCA
ACGCTCGATGCATCGATGCGGCTTGACCCGCACCATCCGGAACTTCTGTTCCAGTTTCTCGCCGATGCGCGCTTTTCTCT
CGGTGAATATCAACAAGCCATCGCCGCGATCGAGCAGCGGCTCCAACAAAACGCGCAATCGGAAACGGCTTACGCCCTGC
TGGCATCATGTTATGGCCATCTCGGCCGCGCGGAGGATGCCCGACAGGCGTGGGAGAAGGCGCTCCAGATCAACCCGGAC
TTCTCCATCGAACGCCGCCGCCGCGTCCTGCCATTCCGAAACCCCGAGGACTTTAACCGCCGCGTCGAAGGACTCCGCAA
GGCTGGACTGCTGGTTCCGGATCTCCGTCAAGGCTAA

Upstream 100 bases:

>100_bases
CAGCGACTACGTGTTCGCCTTTTCTCTGAAAGACGAAGATTAGCGCCGCTGCCGGTCACACTGTGCTATTTTGGTCCGAT
GAGGAACTGAGGCTACGAGC

Downstream 100 bases:

>100_bases
CAGAAACTGCGGCTCAGACCGAAGTCGCATCGCCGCCTGTCGGTGGCCGCAGCATTCATTTTTTCCCGTCCGCCAGCGCC
TCTTTCCCCCGGCGACGCGG

Product: adenylate/guanylate cyclase with TPR repeats

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 3; Adenylyl cyclase 3 [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MTRKLAAILVADVVGYSRLAGADEDRILARLRTLRSDLVDPTIAVHNGRIVKRTGDGSLIEFRSVVDAVRCAIEVQTAMV
ERNIGVPPEHRIEFRVGIHLGDVVEENDGDLMGDGVNIAARLEGVAEPGAICLSEDAYRQVRARLECAVTDLGKVPLKNI
AEPMRVYLLQVGTASQPVSAPQPGEQPAPRRPTAAAVPDKPSIAVLAFNNMSGDAEQEYFSDGISEDIITDLSKLSELHV
IARNSSFVYKNVTASVPEMAKALGVRYVLEGSVRKAGNRVRVTAQLIDASNGGHIWASRYDRDLTDIFAVQDELTQEIVT
ALKLNLTHGDQDRLAQGRAVDVSAYELLLRGREQASAHNRTGNRAARSLAADALAVDPDYAAARALISFTHVLDYVNAWS
DDPEGSLRTGLDLAQQAVDMAEEQPNSHFALGMACMWNHELDRARAEVLRGLALSPNSAELLTLMAHIQIFAGDPAGALA
TLDASMRLDPHHPELLFQFLADARFSLGEYQQAIAAIEQRLQQNAQSETAYALLASCYGHLGRAEDARQAWEKALQINPD
FSIERRRRVLPFRNPEDFNRRVEGLRKAGLLVPDLRQG

Sequences:

>Translated_598_residues
MTRKLAAILVADVVGYSRLAGADEDRILARLRTLRSDLVDPTIAVHNGRIVKRTGDGSLIEFRSVVDAVRCAIEVQTAMV
ERNIGVPPEHRIEFRVGIHLGDVVEENDGDLMGDGVNIAARLEGVAEPGAICLSEDAYRQVRARLECAVTDLGKVPLKNI
AEPMRVYLLQVGTASQPVSAPQPGEQPAPRRPTAAAVPDKPSIAVLAFNNMSGDAEQEYFSDGISEDIITDLSKLSELHV
IARNSSFVYKNVTASVPEMAKALGVRYVLEGSVRKAGNRVRVTAQLIDASNGGHIWASRYDRDLTDIFAVQDELTQEIVT
ALKLNLTHGDQDRLAQGRAVDVSAYELLLRGREQASAHNRTGNRAARSLAADALAVDPDYAAARALISFTHVLDYVNAWS
DDPEGSLRTGLDLAQQAVDMAEEQPNSHFALGMACMWNHELDRARAEVLRGLALSPNSAELLTLMAHIQIFAGDPAGALA
TLDASMRLDPHHPELLFQFLADARFSLGEYQQAIAAIEQRLQQNAQSETAYALLASCYGHLGRAEDARQAWEKALQINPD
FSIERRRRVLPFRNPEDFNRRVEGLRKAGLLVPDLRQG
>Mature_597_residues
TRKLAAILVADVVGYSRLAGADEDRILARLRTLRSDLVDPTIAVHNGRIVKRTGDGSLIEFRSVVDAVRCAIEVQTAMVE
RNIGVPPEHRIEFRVGIHLGDVVEENDGDLMGDGVNIAARLEGVAEPGAICLSEDAYRQVRARLECAVTDLGKVPLKNIA
EPMRVYLLQVGTASQPVSAPQPGEQPAPRRPTAAAVPDKPSIAVLAFNNMSGDAEQEYFSDGISEDIITDLSKLSELHVI
ARNSSFVYKNVTASVPEMAKALGVRYVLEGSVRKAGNRVRVTAQLIDASNGGHIWASRYDRDLTDIFAVQDELTQEIVTA
LKLNLTHGDQDRLAQGRAVDVSAYELLLRGREQASAHNRTGNRAARSLAADALAVDPDYAAARALISFTHVLDYVNAWSD
DPEGSLRTGLDLAQQAVDMAEEQPNSHFALGMACMWNHELDRARAEVLRGLALSPNSAELLTLMAHIQIFAGDPAGALAT
LDASMRLDPHHPELLFQFLADARFSLGEYQQAIAAIEQRLQQNAQSETAYALLASCYGHLGRAEDARQAWEKALQINPDF
SIERRRRVLPFRNPEDFNRRVEGLRKAGLLVPDLRQG

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00515 TPR_1 [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 65401; Mature: 65270

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLAAILVADVVGYSRLAGADEDRILARLRTLRSDLVDPTIAVHNGRIVKRTGDGSLI
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHH
EFRSVVDAVRCAIEVQTAMVERNIGVPPEHRIEFRVGIHLGDVVEENDGDLMGDGVNIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCHHCCCCCCEECCCCEEEH
RLEGVAEPGAICLSEDAYRQVRARLECAVTDLGKVPLKNIAEPMRVYLLQVGTASQPVSA
HHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PQPGEQPAPRRPTAAAVPDKPSIAVLAFNNMSGDAEQEYFSDGISEDIITDLSKLSELHV
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEE
IARNSSFVYKNVTASVPEMAKALGVRYVLEGSVRKAGNRVRVTAQLIDASNGGHIWASRY
EECCCCEEEECCCCCHHHHHHHHCHHHEECCHHHHCCCEEEEEEEEEECCCCCEEEHHHH
DRDLTDIFAVQDELTQEIVTALKLNLTHGDQDRLAQGRAVDVSAYELLLRGREQASAHNR
CCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCCCEECHHHHHHHHHCCHHHHHCCC
TGNRAARSLAADALAVDPDYAAARALISFTHVLDYVNAWSDDPEGSLRTGLDLAQQAVDM
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AEEQPNSHFALGMACMWNHELDRARAEVLRGLALSPNSAELLTLMAHIQIFAGDPAGALA
HHHCCCCCEEEHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCCEE
TLDASMRLDPHHPELLFQFLADARFSLGEYQQAIAAIEQRLQQNAQSETAYALLASCYGH
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
LGRAEDARQAWEKALQINPDFSIERRRRVLPFRNPEDFNRRVEGLRKAGLLVPDLRQG
CCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRKLAAILVADVVGYSRLAGADEDRILARLRTLRSDLVDPTIAVHNGRIVKRTGDGSLI
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHH
EFRSVVDAVRCAIEVQTAMVERNIGVPPEHRIEFRVGIHLGDVVEENDGDLMGDGVNIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCHHCCCCCCEECCCCEEEH
RLEGVAEPGAICLSEDAYRQVRARLECAVTDLGKVPLKNIAEPMRVYLLQVGTASQPVSA
HHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PQPGEQPAPRRPTAAAVPDKPSIAVLAFNNMSGDAEQEYFSDGISEDIITDLSKLSELHV
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEE
IARNSSFVYKNVTASVPEMAKALGVRYVLEGSVRKAGNRVRVTAQLIDASNGGHIWASRY
EECCCCEEEECCCCCHHHHHHHHCHHHEECCHHHHCCCEEEEEEEEEECCCCCEEEHHHH
DRDLTDIFAVQDELTQEIVTALKLNLTHGDQDRLAQGRAVDVSAYELLLRGREQASAHNR
CCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCCCEECHHHHHHHHHCCHHHHHCCC
TGNRAARSLAADALAVDPDYAAARALISFTHVLDYVNAWSDDPEGSLRTGLDLAQQAVDM
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AEEQPNSHFALGMACMWNHELDRARAEVLRGLALSPNSAELLTLMAHIQIFAGDPAGALA
HHHCCCCCEEEHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCCEE
TLDASMRLDPHHPELLFQFLADARFSLGEYQQAIAAIEQRLQQNAQSETAYALLASCYGH
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
LGRAEDARQAWEKALQINPDFSIERRRRVLPFRNPEDFNRRVEGLRKAGLLVPDLRQG
CCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10485295; 11481432 [H]