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The map label for this gene is opuAB [H]

Identifier: 209550403

GI number: 209550403

Start: 2872679

End: 2873524

Strand: Direct

Name: opuAB [H]

Synonym: Rleg2_2824

Alternate gene names: 209550403

Gene position: 2872679-2873524 (Clockwise)

Preceding gene: 209550402

Following gene: 209550404

Centisome position: 63.3

GC content: 61.94

Gene sequence:

>846_bases
TTGAATTGGATCACCGACTTTAAGATTCCCATCGGCCCCTGGGCAAAATCCTTTGTGGACTGGCTCACCTCGAACGGCGC
ATGGTTCTTCGACCAGCTCGCCTCCGTGCTGTCGCACGTTATCGACGGGCTGCTTTTCGTGCTGCAGAAGCCTCACCCGC
TGATCGTCATTGCCGTCATCGCCGCCATTGCCTTCTGGCTGCGCCGATCAATTGCCGTGACCCTCTTCACCTGTCTTGGT
CTGTTGCTGATCATGAACCAGGGCTACTGGAAGGAAACGACGGAGACGCTCGCTCTTGTGCTGGCCTCCACTTTCGTCAG
CATGGTGATTGGCATTCCGCTCGGGATTGCAGCGGCCCGCCGCGCCTGGATCTATGCCGCCATGCGCCCGGCGCTCGATC
TCATGCAGACCATTCCGACGTTCGTCTATCTCATTCCGGCGCTCATCCTGTTCGGCCTCGGCATGGTGCCGGGGCTGATC
GCCACCGTCATCTTCGCGATCCCGGCCCCTATCCGGCTGACGCGCCTCGGCATCATCTCGACGCCGCCTTCGCTTGTAGA
AGCCGCCGTCGCCTTCGGCGCGCGGCCGATGCAGGTGCTGCGCAAGGTCGAGCTTCCCTTCGCCGCGCCGCAGATCATGG
CGGGCCTCACCCAGACCATCATGCTGTCCTTGTCGATGGTGGTCATCGCCGCCCTCGTCGGCGCCGATGGTCTCGGCGTT
CCTGTCGTGCGGGCGCTGAACACCGTCAATGTTGCGAAAGGCTTCGAAGCCGGTCTCTGCATTGTCATCCTGGCGATTAT
TCTCGACCGCATGTTCCGCGCGGCAGGTGAAGGAGACGGAGCATGA

Upstream 100 bases:

>100_bases
CCGCCAAGACCGGTCTCGGCCTTTGATGCTATGAACGGGGCGGCGAGCCGCCCCGTTTCATTTTGTCCATTGTTGATTTT
TTCTGGATAGGCGCGCGCTC

Downstream 100 bases:

>100_bases
CCGCGGTAAGCTTCAAGGATGTCAGCATTATCTTCGGCGACCGGCCGGAAACAGCGCTTGCCATGGCCGATCAGGGCAAG
ACACGTGACGAAATCGGCGC

Product: choline ABC transporter permease

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNWITDFKIPIGPWAKSFVDWLTSNGAWFFDQLASVLSHVIDGLLFVLQKPHPLIVIAVIAAIAFWLRRSIAVTLFTCLG
LLLIMNQGYWKETTETLALVLASTFVSMVIGIPLGIAAARRAWIYAAMRPALDLMQTIPTFVYLIPALILFGLGMVPGLI
ATVIFAIPAPIRLTRLGIISTPPSLVEAAVAFGARPMQVLRKVELPFAAPQIMAGLTQTIMLSLSMVVIAALVGADGLGV
PVVRALNTVNVAKGFEAGLCIVILAIILDRMFRAAGEGDGA

Sequences:

>Translated_281_residues
MNWITDFKIPIGPWAKSFVDWLTSNGAWFFDQLASVLSHVIDGLLFVLQKPHPLIVIAVIAAIAFWLRRSIAVTLFTCLG
LLLIMNQGYWKETTETLALVLASTFVSMVIGIPLGIAAARRAWIYAAMRPALDLMQTIPTFVYLIPALILFGLGMVPGLI
ATVIFAIPAPIRLTRLGIISTPPSLVEAAVAFGARPMQVLRKVELPFAAPQIMAGLTQTIMLSLSMVVIAALVGADGLGV
PVVRALNTVNVAKGFEAGLCIVILAIILDRMFRAAGEGDGA
>Mature_281_residues
MNWITDFKIPIGPWAKSFVDWLTSNGAWFFDQLASVLSHVIDGLLFVLQKPHPLIVIAVIAAIAFWLRRSIAVTLFTCLG
LLLIMNQGYWKETTETLALVLASTFVSMVIGIPLGIAAARRAWIYAAMRPALDLMQTIPTFVYLIPALILFGLGMVPGLI
ATVIFAIPAPIRLTRLGIISTPPSLVEAAVAFGARPMQVLRKVELPFAAPQIMAGLTQTIMLSLSMVVIAALVGADGLGV
PVVRALNTVNVAKGFEAGLCIVILAIILDRMFRAAGEGDGA

Specific function: Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4176

COG function: function code E; ABC-type proline/glycine betaine transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789033, Length=272, Percent_Identity=43.0147058823529, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788449, Length=224, Percent_Identity=31.25, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788451, Length=244, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30147; Mature: 30147

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7622480; 8969502; 9384377 [H]