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The map label for this gene is engD [H]

Identifier: 209550350

GI number: 209550350

Start: 2815643

End: 2816746

Strand: Direct

Name: engD [H]

Synonym: Rleg2_2771

Alternate gene names: 209550350

Gene position: 2815643-2816746 (Clockwise)

Preceding gene: 209550348

Following gene: 209550352

Centisome position: 62.05

GC content: 62.5

Gene sequence:

>1104_bases
ATGGGCTTCAAATGCGGCATCGTCGGTCTGCCGAACGTCGGCAAATCGACCCTCTTCAACGCGCTCACCAAGACGGCGGC
CGCACAGGCGGCGAACTATCCCTTCTGCACCATCGAGCCGAACACCGGTGAAGTCGCCGTGCCCGATCCGCGCATGCGCA
AGCTTGCCGACATCGCCAAGTCGAAAGAACTGATCCCGACCCGCATCTCCTTCGTCGACATCGCCGGCCTGGTGCGCGGC
GCCTCGAAGGGTGAAGGCCTCGGCAACCAGTTCCTTGCCAATATCCGCGAAGTCGACGCCATCGTGCATGTGCTGCGTTG
TTTTGAAGACAGCGACATCACCCATGTCGAGGGCCGCATCAATCCCGTCGCCGATGCCGAGACCATCGAGACCGAGCTGA
TGCTCGCCGACCTCGAAAGCCTCGAGCGCCGCACCGAGCAGACGCGCAAGCGCGCCACCAGCAAGGACAAGGAATCGATG
GCGATGCTGCCGATCATGGAAGCGTCGCTGAAATTGCTCAACGAAGGCAAGCCGGTGCGCACCCTGCTGTCGACGCTGGA
CGCCGAGGAAATCGCCATCCTCAAGGGCCTCAATCTCCTGACCTCGCATCCGGTGCTCTATGTCTGCAACGTCGCCGAGG
CCGAGGCTTCGACCGGCAATGAATTCACCGAAGCCGTCGCCGTCATGGCTCGGGAACAGGGTGCTGAAACCGTCGTCATC
TCGGCGGCGATCGAGGCCGAGGTCGCTCAGCTTCCCGAGGATGAGGCCAAGGAATTCCTCTCCGCCCTCGACCTTGACGA
GGCAGGCCTCGACCGGCTGATCCGCGCCGGCTACAAGCTGCTCCACCTCATCACCTATTTCACCGTCGGCCCGAAGGAAA
CGCGCGCCTGGACGATCGAGCGCGGCACCAAGGCGCCGCAGGCCGCCGGCGTCATCCATTCGGATTTCGAGCGCGGCTTC
ATCCGCGCCAACACCATCGCCTATGACGATTACATCAAGTACAACGGCGAAGTCGGCGCCAAGGATGCCGGCAAGGCGCG
TGACGAAGGCAAGGAATACGTCGTCCAGGACGGCGACGTTATCCACTTCCGTTTCAATACCTGA

Upstream 100 bases:

>100_bases
TGAGCAAGTGAGCAACGCTAAAAGCTCGCTAAGACTTGACCACATTGCTCCTTTATCCCATAGGCACCAGCAAGAAATTC
AAGAACAGCAGGTTTTAGCC

Downstream 100 bases:

>100_bases
TGCGAACAGGCTGCCGCCTCAACCCGGCGGCAGCCTGTTTGCAATTGCCGGCGGCAGGGCGCGCAGCACCAGCCGCCGAA
GCGGCATCCAACCGGTGCCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRKLADIAKSKELIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDSDITHVEGRINPVADAETIETELMLADLESLERRTEQTRKRATSKDKESM
AMLPIMEASLKLLNEGKPVRTLLSTLDAEEIAILKGLNLLTSHPVLYVCNVAEAEASTGNEFTEAVAVMAREQGAETVVI
SAAIEAEVAQLPEDEAKEFLSALDLDEAGLDRLIRAGYKLLHLITYFTVGPKETRAWTIERGTKAPQAAGVIHSDFERGF
IRANTIAYDDYIKYNGEVGAKDAGKARDEGKEYVVQDGDVIHFRFNT

Sequences:

>Translated_367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRKLADIAKSKELIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDSDITHVEGRINPVADAETIETELMLADLESLERRTEQTRKRATSKDKESM
AMLPIMEASLKLLNEGKPVRTLLSTLDAEEIAILKGLNLLTSHPVLYVCNVAEAEASTGNEFTEAVAVMAREQGAETVVI
SAAIEAEVAQLPEDEAKEFLSALDLDEAGLDRLIRAGYKLLHLITYFTVGPKETRAWTIERGTKAPQAAGVIHSDFERGF
IRANTIAYDDYIKYNGEVGAKDAGKARDEGKEYVVQDGDVIHFRFNT
>Mature_366_residues
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRKLADIAKSKELIPTRISFVDIAGLVRGA
SKGEGLGNQFLANIREVDAIVHVLRCFEDSDITHVEGRINPVADAETIETELMLADLESLERRTEQTRKRATSKDKESMA
MLPIMEASLKLLNEGKPVRTLLSTLDAEEIAILKGLNLLTSHPVLYVCNVAEAEASTGNEFTEAVAVMAREQGAETVVIS
AAIEAEVAQLPEDEAKEFLSALDLDEAGLDRLIRAGYKLLHLITYFTVGPKETRAWTIERGTKAPQAAGVIHSDFERGFI
RANTIAYDDYIKYNGEVGAKDAGKARDEGKEYVVQDGDVIHFRFNT

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=43.2432432432432, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI58761502, Length=199, Percent_Identity=39.1959798994975, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=56.8306010928962, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=33.0769230769231, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=42.6630434782609, Blast_Score=290, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=40.3743315508021, Blast_Score=267, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.9393139841689, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321649, Length=308, Percent_Identity=28.2467532467532, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.6666666666667, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.6666666666667, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.6666666666667, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640879, Length=333, Percent_Identity=39.039039039039, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40027; Mature: 39896

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRKLADIAK
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKELIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDSDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
NPVADAETIETELMLADLESLERRTEQTRKRATSKDKESMAMLPIMEASLKLLNEGKPVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
TLLSTLDAEEIAILKGLNLLTSHPVLYVCNVAEAEASTGNEFTEAVAVMAREQGAETVVI
HHHHHCCHHHHHHHHCCHHHHCCCEEEEEECHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLPEDEAKEFLSALDLDEAGLDRLIRAGYKLLHLITYFTVGPKETRAWTIE
EHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RGTKAPQAAGVIHSDFERGFIRANTIAYDDYIKYNGEVGAKDAGKARDEGKEYVVQDGDV
CCCCCCHHHCCHHHHHHCCCEEECEEEECCCEEECCCCCCCCCCCCHHCCCEEEEECCCE
IHFRFNT
EEEEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRKLADIAK
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKELIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDSDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
NPVADAETIETELMLADLESLERRTEQTRKRATSKDKESMAMLPIMEASLKLLNEGKPVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
TLLSTLDAEEIAILKGLNLLTSHPVLYVCNVAEAEASTGNEFTEAVAVMAREQGAETVVI
HHHHHCCHHHHHHHHCCHHHHCCCEEEEEECHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLPEDEAKEFLSALDLDEAGLDRLIRAGYKLLHLITYFTVGPKETRAWTIE
EHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RGTKAPQAAGVIHSDFERGFIRANTIAYDDYIKYNGEVGAKDAGKARDEGKEYVVQDGDV
CCCCCCHHHCCHHHHHHCCCEEECEEEECCCEEECCCCCCCCCCCCHHCCCEEEEECCCE
IHFRFNT
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA