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The map label for this gene is iolS [H]

Identifier: 209550290

GI number: 209550290

Start: 2751836

End: 2752828

Strand: Direct

Name: iolS [H]

Synonym: Rleg2_2710

Alternate gene names: 209550290

Gene position: 2751836-2752828 (Clockwise)

Preceding gene: 209550287

Following gene: 209550292

Centisome position: 60.64

GC content: 63.95

Gene sequence:

>993_bases
ATGCTGACCTATCGTTTGGGAAAGACCGGACCCGATGTTTCGGCCATCGGCCTCGGCTGCATGGGCATGTCGGGCATGTA
CGGCCCTGCCGACCGCGCCGAAAGTATCGCGACGATCCATGCCGCGCTCGATGCCGGCGTCAATCTGCTGGACACCGGCG
ATTTCTACGGCATGGGCCATAATGAGATGCTGATTGGGGAGGCGTTGAAGGGTCGCAGGCGCGAGGATGCCGTCATCAGC
GTCAAATTCGGCGCGCTCCGCGATCCCGCCAGCGGCTGGAGCGGCATCGACGCCCGCCCGGGCGCGGTGAAGAACTTCCT
CGCTTACACGCTGCAGCGTCTCGGCGTCGATTATATTGACATCTACCGCCCGGCCCGCCTCGATCCGAACGTGCCGATCG
AGGATACGGTTGGCGCGATCGCCGACATGGTCAAAGCGGGTTATGTCAGGCATATCGGCCTGTCCGAAGTCGGCGCCGAC
ACCATCCGCCGCGCCGCCGCCGTTGCCCCGATCGTCGACCTGCAAATCGAATATTCGCTGATCTCGCGCGGCATCGAAGA
GAAGATCCTGCCGACGACACGCGAACTCGGCATCTCGATCACCGCTTACGGCGTGCTCTCGCGCGGCCTGATCAGCGGCC
ATTGGCAAAAGGGCCAGGCCGCGGCCGGAGACTTCCGCACCCATAGCCCACGCTTCCAGGCGAGCAATATCGAGCAGAAC
CTCGCTTTGGTGGAAAAACTGCGGGAGATCGCGGAGGCAAAGAGCGTCTCGGTCGCCCAGATCGCCATCGCCTGGGTCGC
CGCCAAGGGCAAGGATATCGTCCCGATCATCGGCGCCCGCCGCCGCGACCGGCTGACCGAGGCTCTCGGCTCACGCGCGG
TGGATCTGTCGGCAGAAGATTTCGCCGCGATCGAACGCGCCGTCCCGAAGGATGCGGCTGCCGGCGGGCGTTATCCCGAA
CATATGCTGCAGCATATGGATAGTGAGAGATAG

Upstream 100 bases:

>100_bases
CGCACGGCCCGTTCGAGACCATCCGGATTATCGCGCAGGGGCGAAGGCTGTAAAAAGGGCATCCGGCAGCGCCGTTCGGG
CGCGGATTAGGGAGAAGACA

Downstream 100 bases:

>100_bases
TGAATTGGGGCGGAGGATTTAAACTATCGTCCTGCCGTGCAGCCCCCTCATCCGACCCTTCGGGCCACCTTCTCCCCGCT
GGGGAGAAGAGGGAGCAAGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLTYRLGKTGPDVSAIGLGCMGMSGMYGPADRAESIATIHAALDAGVNLLDTGDFYGMGHNEMLIGEALKGRRREDAVIS
VKFGALRDPASGWSGIDARPGAVKNFLAYTLQRLGVDYIDIYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEVGAD
TIRRAAAVAPIVDLQIEYSLISRGIEEKILPTTRELGISITAYGVLSRGLISGHWQKGQAAAGDFRTHSPRFQASNIEQN
LALVEKLREIAEAKSVSVAQIAIAWVAAKGKDIVPIIGARRRDRLTEALGSRAVDLSAEDFAAIERAVPKDAAAGGRYPE
HMLQHMDSER

Sequences:

>Translated_330_residues
MLTYRLGKTGPDVSAIGLGCMGMSGMYGPADRAESIATIHAALDAGVNLLDTGDFYGMGHNEMLIGEALKGRRREDAVIS
VKFGALRDPASGWSGIDARPGAVKNFLAYTLQRLGVDYIDIYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEVGAD
TIRRAAAVAPIVDLQIEYSLISRGIEEKILPTTRELGISITAYGVLSRGLISGHWQKGQAAAGDFRTHSPRFQASNIEQN
LALVEKLREIAEAKSVSVAQIAIAWVAAKGKDIVPIIGARRRDRLTEALGSRAVDLSAEDFAAIERAVPKDAAAGGRYPE
HMLQHMDSER
>Mature_330_residues
MLTYRLGKTGPDVSAIGLGCMGMSGMYGPADRAESIATIHAALDAGVNLLDTGDFYGMGHNEMLIGEALKGRRREDAVIS
VKFGALRDPASGWSGIDARPGAVKNFLAYTLQRLGVDYIDIYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEVGAD
TIRRAAAVAPIVDLQIEYSLISRGIEEKILPTTRELGISITAYGVLSRGLISGHWQKGQAAAGDFRTHSPRFQASNIEQN
LALVEKLREIAEAKSVSVAQIAIAWVAAKGKDIVPIIGARRRDRLTEALGSRAVDLSAEDFAAIERAVPKDAAAGGRYPE
HMLQHMDSER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=29.9674267100977, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=29.9674267100977, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436966, Length=302, Percent_Identity=29.8013245033113, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=30.3225806451613, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223718702, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41327764, Length=242, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI41152114, Length=254, Percent_Identity=24.0157480314961, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=32.4921135646688, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=30.7692307692308, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=26.7267267267267, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789199, Length=340, Percent_Identity=27.9411764705882, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=27.2435897435897, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788081, Length=283, Percent_Identity=25.0883392226148, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=317, Percent_Identity=26.1829652996845, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=26.2048192771084, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=332, Percent_Identity=26.2048192771084, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=303, Percent_Identity=26.4026402640264, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=25.752508361204, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=264, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=299, Percent_Identity=24.0802675585284, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=342, Percent_Identity=28.0701754385965, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549126, Length=342, Percent_Identity=28.0701754385965, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646159, Length=280, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646155, Length=313, Percent_Identity=27.4760383386581, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35431; Mature: 35431

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYRLGKTGPDVSAIGLGCMGMSGMYGPADRAESIATIHAALDAGVNLLDTGDFYGMGH
CCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NEMLIGEALKGRRREDAVISVKFGALRDPASGWSGIDARPGAVKNFLAYTLQRLGVDYID
CCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEVGADTIRRAAAVAPIVDLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHEEEHHH
ISRGIEEKILPTTRELGISITAYGVLSRGLISGHWQKGQAAAGDFRTHSPRFQASNIEQN
HHCCHHHHHCCCHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LALVEKLREIAEAKSVSVAQIAIAWVAAKGKDIVPIIGARRRDRLTEALGSRAVDLSAED
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCEECCCHHH
FAAIERAVPKDAAAGGRYPEHMLQHMDSER
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MLTYRLGKTGPDVSAIGLGCMGMSGMYGPADRAESIATIHAALDAGVNLLDTGDFYGMGH
CCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NEMLIGEALKGRRREDAVISVKFGALRDPASGWSGIDARPGAVKNFLAYTLQRLGVDYID
CCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEVGADTIRRAAAVAPIVDLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHEEEHHH
ISRGIEEKILPTTRELGISITAYGVLSRGLISGHWQKGQAAAGDFRTHSPRFQASNIEQN
HHCCHHHHHCCCHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LALVEKLREIAEAKSVSVAQIAIAWVAAKGKDIVPIIGARRRDRLTEALGSRAVDLSAED
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCEECCCHHH
FAAIERAVPKDAAAGGRYPEHMLQHMDSER
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]