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The map label for this gene is yrpG [H]

Identifier: 209550067

GI number: 209550067

Start: 2517310

End: 2518368

Strand: Direct

Name: yrpG [H]

Synonym: Rleg2_2484

Alternate gene names: 209550067

Gene position: 2517310-2518368 (Clockwise)

Preceding gene: 209550066

Following gene: 209550068

Centisome position: 55.47

GC content: 63.46

Gene sequence:

>1059_bases
ATGGAATATCGTTCGCTCGGCCGTTCCGGCCTGAAGATCTCCACATTGACCATGGGCACCATGACCTTCGGCGGCGTCGG
ATGGGCCAAGACCGTCGGGGACCTCGGCGTCTCCGAGGCGCGGAAGATGATCGATATCTGCATCGATGCCGGCATCAACC
TCATCGACACCGCCAATGCCTATTCCAACGGCGAATGCGAAAACATCATCGGCGACGTGCTCTCCGGCAAGCGGCCGCAA
GGCGTGCTGCTTGCCACCAAGGCCCGTTTCGGCATGGGTGACGGCCCGAACGACCAAGGACTGTCGCGCTACCACCTGAT
CCGGGAATGCGAAGCGAGCCTCAAACGCCTGAAGACCGATGTCATCGACCTGTACCAGGTGCATGAATGGGACGGCCAGA
CGCCGCTCGAAGAGACGATGGAAGCCCTCGACACGCTGATCAAGCAGGGCAAGGTGCGTTACGTCGGCTGCTCGAACTAT
TCCGGCTGGCACATCATGAAGGCGCTTGGCATCGCCAACGAGCACCGCTACCAGCGCTTCATCAGCCAGCAGATCCACTA
TACGCTGGAAGCGCGCGACGCCGAATACGAGCTGCTGCCGATTTCGATCGACCAGGGCCTCGGCGTGCTGGTCTGGAGCC
CGCTTGCCGGCGGCCTGCTCTCCGGCAAACACCGCCGCAACCAAGCCGCTCCCGAAGGCACGCGGCAGTTCGCCGGCTGG
ACCGAACCGCCGATCCGTGACGAGAACCGTCTCTGGAACATCGTCGAGACGCTGGTCGCGATCGGGCAGGAGCGCGGCGT
CTCGGCCGCACAAGTGGCGCTCGCCTGGCTGATCGGCCGCAAGGCGGTCACCTCGGTCATCATCGGCGGGCGCACAGAAG
CCCAGTTCCGCGACAACATCGCCGCCGCCGAACTGAAGCTCACGAACGAGGAGCGCAAGCGCCTGGATGCCGTCAGCCTG
CCGCCGGTGATCTATCCCTATTGGCACCAGCTGAACACGGTGAGCGACAGGCTTGGTGAAGCCGATCTCGAGCTGTTCGG
CCCGCATCTTCAGCAATAG

Upstream 100 bases:

>100_bases
CGAAATCTTGCCTAGCCTCACGCAGGCGTGAATACCCAGCCATTGCCATTCCGCCGCGCTGAGGTACGTCAATCGTGTTT
TCGATGAAGGAGGAGTTTCA

Downstream 100 bases:

>100_bases
GCGATGACGAACCAGGCATTGCACGGCGAAAGACAGGCGTCATAAAAGATGCACTTTCGCCGTGTTAGCGTAAGAGCCCG
CTACTCCTGCGAGGTTCGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MEYRSLGRSGLKISTLTMGTMTFGGVGWAKTVGDLGVSEARKMIDICIDAGINLIDTANAYSNGECENIIGDVLSGKRPQ
GVLLATKARFGMGDGPNDQGLSRYHLIRECEASLKRLKTDVIDLYQVHEWDGQTPLEETMEALDTLIKQGKVRYVGCSNY
SGWHIMKALGIANEHRYQRFISQQIHYTLEARDAEYELLPISIDQGLGVLVWSPLAGGLLSGKHRRNQAAPEGTRQFAGW
TEPPIRDENRLWNIVETLVAIGQERGVSAAQVALAWLIGRKAVTSVIIGGRTEAQFRDNIAAAELKLTNEERKRLDAVSL
PPVIYPYWHQLNTVSDRLGEADLELFGPHLQQ

Sequences:

>Translated_352_residues
MEYRSLGRSGLKISTLTMGTMTFGGVGWAKTVGDLGVSEARKMIDICIDAGINLIDTANAYSNGECENIIGDVLSGKRPQ
GVLLATKARFGMGDGPNDQGLSRYHLIRECEASLKRLKTDVIDLYQVHEWDGQTPLEETMEALDTLIKQGKVRYVGCSNY
SGWHIMKALGIANEHRYQRFISQQIHYTLEARDAEYELLPISIDQGLGVLVWSPLAGGLLSGKHRRNQAAPEGTRQFAGW
TEPPIRDENRLWNIVETLVAIGQERGVSAAQVALAWLIGRKAVTSVIIGGRTEAQFRDNIAAAELKLTNEERKRLDAVSL
PPVIYPYWHQLNTVSDRLGEADLELFGPHLQQ
>Mature_352_residues
MEYRSLGRSGLKISTLTMGTMTFGGVGWAKTVGDLGVSEARKMIDICIDAGINLIDTANAYSNGECENIIGDVLSGKRPQ
GVLLATKARFGMGDGPNDQGLSRYHLIRECEASLKRLKTDVIDLYQVHEWDGQTPLEETMEALDTLIKQGKVRYVGCSNY
SGWHIMKALGIANEHRYQRFISQQIHYTLEARDAEYELLPISIDQGLGVLVWSPLAGGLLSGKHRRNQAAPEGTRQFAGW
TEPPIRDENRLWNIVETLVAIGQERGVSAAQVALAWLIGRKAVTSVIIGGRTEAQFRDNIAAAELKLTNEERKRLDAVSL
PPVIYPYWHQLNTVSDRLGEADLELFGPHLQQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=329, Percent_Identity=31.9148936170213, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI27436962, Length=329, Percent_Identity=31.9148936170213, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=32.8267477203647, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI27436966, Length=329, Percent_Identity=31.6109422492401, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=32.7217125382263, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=28.2674772036474, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI223718702, Length=273, Percent_Identity=29.6703296703297, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=29.1970802919708, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41152114, Length=276, Percent_Identity=30.0724637681159, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718708, Length=122, Percent_Identity=34.4262295081967, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=36.4741641337386, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789199, Length=355, Percent_Identity=30.9859154929577, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=31.8181818181818, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=31.3432835820896, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788081, Length=277, Percent_Identity=33.2129963898917, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI48994888, Length=333, Percent_Identity=22.5225225225225, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=32.7380952380952, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=29.7872340425532, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319958, Length=306, Percent_Identity=28.7581699346405, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=346, Percent_Identity=27.4566473988439, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=239, Percent_Identity=29.7071129707113, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=33.1288343558282, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640980, Length=328, Percent_Identity=26.8292682926829, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45549126, Length=328, Percent_Identity=26.8292682926829, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24646155, Length=321, Percent_Identity=29.595015576324, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=26.3473053892216, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38999; Mature: 38999

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRSLGRSGLKISTLTMGTMTFGGVGWAKTVGDLGVSEARKMIDICIDAGINLIDTANA
CCCHHCCCCCCEEEEEEECCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCC
YSNGECENIIGDVLSGKRPQGVLLATKARFGMGDGPNDQGLSRYHLIRECEASLKRLKTD
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIDLYQVHEWDGQTPLEETMEALDTLIKQGKVRYVGCSNYSGWHIMKALGIANEHRYQRF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHH
ISQQIHYTLEARDAEYELLPISIDQGLGVLVWSPLAGGLLSGKHRRNQAAPEGTRQFAGW
HHHHHHEEEEECCCCEEEEEEECCCCCCEEEECCHHCHHHCCCHHCCCCCCCHHHHCCCC
TEPPIRDENRLWNIVETLVAIGQERGVSAAQVALAWLIGRKAVTSVIIGGRTEAQFRDNI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCH
AAAELKLTNEERKRLDAVSLPPVIYPYWHQLNTVSDRLGEADLELFGPHLQQ
HHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHCCC
>Mature Secondary Structure
MEYRSLGRSGLKISTLTMGTMTFGGVGWAKTVGDLGVSEARKMIDICIDAGINLIDTANA
CCCHHCCCCCCEEEEEEECCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCC
YSNGECENIIGDVLSGKRPQGVLLATKARFGMGDGPNDQGLSRYHLIRECEASLKRLKTD
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIDLYQVHEWDGQTPLEETMEALDTLIKQGKVRYVGCSNYSGWHIMKALGIANEHRYQRF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHH
ISQQIHYTLEARDAEYELLPISIDQGLGVLVWSPLAGGLLSGKHRRNQAAPEGTRQFAGW
HHHHHHEEEEECCCCEEEEEEECCCCCCEEEECCHHCHHHCCCHHCCCCCCCHHHHCCCC
TEPPIRDENRLWNIVETLVAIGQERGVSAAQVALAWLIGRKAVTSVIIGGRTEAQFRDNI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCH
AAAELKLTNEERKRLDAVSLPPVIYPYWHQLNTVSDRLGEADLELFGPHLQQ
HHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]