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The map label for this gene is ytfL [C]

Identifier: 209549972

GI number: 209549972

Start: 2449256

End: 2450584

Strand: Direct

Name: ytfL [C]

Synonym: Rleg2_2388

Alternate gene names: 209549972

Gene position: 2449256-2450584 (Clockwise)

Preceding gene: 209549971

Following gene: 209549975

Centisome position: 53.97

GC content: 62.68

Gene sequence:

>1329_bases
ATGTCCGAATCCGCGGGCGGCGTCTTCGACTATGTCGGGATACTCGCCGTGCTTCTACTGGTGGCCGCCAACGGCTTCTT
CGTCGCTGCGGAATTCGCGCTGGTGTCCGTCAGGCGCAGCCGTGTCACCGAACTTGCCGCTGCAGGCCGCATGAATGCCT
CCGCCCTACAGCGCGCCGTCGACAATCTCGATGCCAATCTCGCCGCCACCCAGCTCGGTATCACCATCTCGTCGCTGGCA
CTGGGCTGGGTCGGCGAGCCGGCGCTTGCCCACTTGATCGAGCCTCTGCTGTCCTGGCTGCCCGGGCAATGGGCGGCAAC
AGGCGCGCATACCGTCGCCATCGTCATTGCCTTCGTCATCATTACGGCACTGCACATCGTGCTGGGCGAGCTGGCGCCGA
AAAGCCTGGCGCTTCAGCGCAGTGAGGCCACTTCGCTTGCCGTAGTGCGTCCGCTGGGGCTCTTCCTGGTGCTGTTCAAG
CCGGCGATCTTCGTTCTGAACGGCATGGGCAACCTTGTGCTGCGGGGCGTCGGCCTTCGCGCCGGAACCGGGGAATCGTC
GTTCCATTCGCCGCAGGAACTCAAGCTGCTGGTCGCCGAAAGTCAGGAAGCCGGTCTTCTCAATCAGGTGCAGCAGCAGC
TCGTCGAGCGGGTGTTCAACATCGGCGACAGACCGATCTCCGACATCATGACCCCGCGTCTCGATATCGAATGGTTCGAT
GCCGACGACAGCGAGGCCGAGATTCTGAAGACCATCCGTGAATGCAGCCACGAACAATTGCTGGTCGCCCGCGGCTCGAT
CGACGAACCGATCGGCATGGTGTTGAAGAAGGACCTTCTCGACCAGGTTCTCGACGGCGGCAAGGTCCGGCCGATGGAGG
TGATCAAGCAGCCGCTGGTGCTGCACGAGGGCACCTCGGTCGTGCGTGTGCTCGACAGTTTCAAGGCCTCGCCTGTCCGG
CTCGCCATCGTCATCGATGAATATGGCAGCCTTGAGGGTATCGTCACCCAGACCGACCTGCTCGAAGCGATCGCCGGCGA
CCTGCCGGGATCCAATGAGGAGCCCGATATCATCGTGCGGGAAGACGGATCGCTCTTGATCGATGCGATGATGCCCGCCT
TCGACGCCTTCGAGCGGCTCGGTCTGCGCGATCGTCCGGATGCCGATTTCCATACGCTTGCAGGCTTCGCGCTGCACCAG
CTCCAGCACATCCCGGAAGCCGGCGAAACCTTCGTTTTCGATAGCTGGCGCTTCGAAGTTCTCGATATGGACGGCATGCG
CATCGACAAAATGCTGGCAACGCGCATCCCCGCGGACGGGGAAGGCTGA

Upstream 100 bases:

>100_bases
CCGCATCGACATCGCTCACAGCAAGAATGGCTGCCGCGCCTTGCTACCTCTGTCCGAGCGTGTAGTTTCGGATTGGGATC
AATTCAGAGGTAGGGAAAAT

Downstream 100 bases:

>100_bases
TGCATGTCGCCCGGAAGTGTGCAGCAGTTCCGGGCGACATGCATAAAAAAGAGATCTAACCCACCGCCAGCGTCCAGAGC
ATTCCCGATATCGCACAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSESAGGVFDYVGILAVLLLVAANGFFVAAEFALVSVRRSRVTELAAAGRMNASALQRAVDNLDANLAATQLGITISSLA
LGWVGEPALAHLIEPLLSWLPGQWAATGAHTVAIVIAFVIITALHIVLGELAPKSLALQRSEATSLAVVRPLGLFLVLFK
PAIFVLNGMGNLVLRGVGLRAGTGESSFHSPQELKLLVAESQEAGLLNQVQQQLVERVFNIGDRPISDIMTPRLDIEWFD
ADDSEAEILKTIRECSHEQLLVARGSIDEPIGMVLKKDLLDQVLDGGKVRPMEVIKQPLVLHEGTSVVRVLDSFKASPVR
LAIVIDEYGSLEGIVTQTDLLEAIAGDLPGSNEEPDIIVREDGSLLIDAMMPAFDAFERLGLRDRPDADFHTLAGFALHQ
LQHIPEAGETFVFDSWRFEVLDMDGMRIDKMLATRIPADGEG

Sequences:

>Translated_442_residues
MSESAGGVFDYVGILAVLLLVAANGFFVAAEFALVSVRRSRVTELAAAGRMNASALQRAVDNLDANLAATQLGITISSLA
LGWVGEPALAHLIEPLLSWLPGQWAATGAHTVAIVIAFVIITALHIVLGELAPKSLALQRSEATSLAVVRPLGLFLVLFK
PAIFVLNGMGNLVLRGVGLRAGTGESSFHSPQELKLLVAESQEAGLLNQVQQQLVERVFNIGDRPISDIMTPRLDIEWFD
ADDSEAEILKTIRECSHEQLLVARGSIDEPIGMVLKKDLLDQVLDGGKVRPMEVIKQPLVLHEGTSVVRVLDSFKASPVR
LAIVIDEYGSLEGIVTQTDLLEAIAGDLPGSNEEPDIIVREDGSLLIDAMMPAFDAFERLGLRDRPDADFHTLAGFALHQ
LQHIPEAGETFVFDSWRFEVLDMDGMRIDKMLATRIPADGEG
>Mature_441_residues
SESAGGVFDYVGILAVLLLVAANGFFVAAEFALVSVRRSRVTELAAAGRMNASALQRAVDNLDANLAATQLGITISSLAL
GWVGEPALAHLIEPLLSWLPGQWAATGAHTVAIVIAFVIITALHIVLGELAPKSLALQRSEATSLAVVRPLGLFLVLFKP
AIFVLNGMGNLVLRGVGLRAGTGESSFHSPQELKLLVAESQEAGLLNQVQQQLVERVFNIGDRPISDIMTPRLDIEWFDA
DDSEAEILKTIRECSHEQLLVARGSIDEPIGMVLKKDLLDQVLDGGKVRPMEVIKQPLVLHEGTSVVRVLDSFKASPVRL
AIVIDEYGSLEGIVTQTDLLEAIAGDLPGSNEEPDIIVREDGSLLIDAMMPAFDAFERLGLRDRPDADFHTLAGFALHQL
QHIPEAGETFVFDSWRFEVLDMDGMRIDKMLATRIPADGEG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=374, Percent_Identity=32.3529411764706, Blast_Score=208, Evalue=6e-54,
Organism=Escherichia coli, GI1790664, Length=433, Percent_Identity=28.6374133949192, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082033, Length=241, Percent_Identity=34.4398340248963, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI145693175, Length=409, Percent_Identity=23.7163814180929, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=29.5652173913043, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=29.7619047619048, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47728; Mature: 47597

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAGGVFDYVGILAVLLLVAANGFFVAAEFALVSVRRSRVTELAAAGRMNASALQRAV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DNLDANLAATQLGITISSLALGWVGEPALAHLIEPLLSWLPGQWAATGAHTVAIVIAFVI
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ITALHIVLGELAPKSLALQRSEATSLAVVRPLGLFLVLFKPAIFVLNGMGNLVLRGVGLR
HHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCC
AGTGESSFHSPQELKLLVAESQEAGLLNQVQQQLVERVFNIGDRPISDIMTPRLDIEWFD
CCCCCCCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
ADDSEAEILKTIRECSHEQLLVARGSIDEPIGMVLKKDLLDQVLDGGKVRPMEVIKQPLV
CCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHH
LHEGTSVVRVLDSFKASPVRLAIVIDEYGSLEGIVTQTDLLEAIAGDLPGSNEEPDIIVR
EECCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEEE
EDGSLLIDAMMPAFDAFERLGLRDRPDADFHTLAGFALHQLQHIPEAGETFVFDSWRFEV
CCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
LDMDGMRIDKMLATRIPADGEG
EECCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SESAGGVFDYVGILAVLLLVAANGFFVAAEFALVSVRRSRVTELAAAGRMNASALQRAV
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DNLDANLAATQLGITISSLALGWVGEPALAHLIEPLLSWLPGQWAATGAHTVAIVIAFVI
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ITALHIVLGELAPKSLALQRSEATSLAVVRPLGLFLVLFKPAIFVLNGMGNLVLRGVGLR
HHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCC
AGTGESSFHSPQELKLLVAESQEAGLLNQVQQQLVERVFNIGDRPISDIMTPRLDIEWFD
CCCCCCCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
ADDSEAEILKTIRECSHEQLLVARGSIDEPIGMVLKKDLLDQVLDGGKVRPMEVIKQPLV
CCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHH
LHEGTSVVRVLDSFKASPVRLAIVIDEYGSLEGIVTQTDLLEAIAGDLPGSNEEPDIIVR
EECCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEEE
EDGSLLIDAMMPAFDAFERLGLRDRPDADFHTLAGFALHQLQHIPEAGETFVFDSWRFEV
CCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
LDMDGMRIDKMLATRIPADGEG
EECCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]