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The map label for this gene is ribH [H]

Identifier: 209549947

GI number: 209549947

Start: 2423501

End: 2423935

Strand: Direct

Name: ribH [H]

Synonym: Rleg2_2363

Alternate gene names: 209549947

Gene position: 2423501-2423935 (Clockwise)

Preceding gene: 209549944

Following gene: 209549948

Centisome position: 53.41

GC content: 64.37

Gene sequence:

>435_bases
ATGACACCCACCCGCTACGCCTTTATCAAAGCCAGCTGGCACGCCGACATCGTCGACCGCGCCCTTGACGGCTTCTACCA
GCTCGTGCCGCCCGAGCAGGTCGACGTGTTCGATGTTCCCGGCGCCTTCGAAATGCCGCTGCTTTCACGCGATCTCGCCG
CAACCGGACGCTATGCCGCCGTCGTTGCCGCCGCTTTCGTCGTCGACGGCGGAATTTACCGCCATGAATTCGTCGCCCAG
GCCGTGGTCGACGGGCTGATGCGCGCCGGCATGGATACCGGCGTGCCGGTGCTGTCGGTTTCGCTGACGCCGCATCAATA
TCAAGAAACCGACCACCACAAGCAGATCTACCGGGCACACTTCGTCGAGAAAGGGCGGGAGGCCGCAAAGGCCGCGCTGA
CGATCGGCAAGACACGCGCCGCACTTGCCGCGTAG

Upstream 100 bases:

>100_bases
GTCCGGATGAAAGAGAACGTGCGTTCCTGCCGCCCTTGCGGCTGTCGGGGACGTTCGTGATCGCCTTGGGTGATGTGTCT
GTTCGCCAAAGGAGATTACC

Downstream 100 bases:

>100_bases
CAAGGCTGATCCTCGAACCGAGGCGGCGGGACCGATCCCGCCGTCTTCATCAGGTCAATTCCGACAGAATAATTGATTCG
ACGCCCTCGCCGCGCTGTGG

Product: riboflavin synthase subunit beta

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MTPTRYAFIKASWHADIVDRALDGFYQLVPPEQVDVFDVPGAFEMPLLSRDLAATGRYAAVVAAAFVVDGGIYRHEFVAQ
AVVDGLMRAGMDTGVPVLSVSLTPHQYQETDHHKQIYRAHFVEKGREAAKAALTIGKTRAALAA

Sequences:

>Translated_144_residues
MTPTRYAFIKASWHADIVDRALDGFYQLVPPEQVDVFDVPGAFEMPLLSRDLAATGRYAAVVAAAFVVDGGIYRHEFVAQ
AVVDGLMRAGMDTGVPVLSVSLTPHQYQETDHHKQIYRAHFVEKGREAAKAALTIGKTRAALAA
>Mature_143_residues
TPTRYAFIKASWHADIVDRALDGFYQLVPPEQVDVFDVPGAFEMPLLSRDLAATGRYAAVVAAAFVVDGGIYRHEFVAQA
VVDGLMRAGMDTGVPVLSVSLTPHQYQETDHHKQIYRAHFVEKGREAAKAALTIGKTRAALAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=121, Percent_Identity=34.7107438016529, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 15699; Mature: 15568

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTRYAFIKASWHADIVDRALDGFYQLVPPEQVDVFDVPGAFEMPLLSRDLAATGRYAA
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCHHHH
VVAAAFVVDGGIYRHEFVAQAVVDGLMRAGMDTGVPVLSVSLTPHQYQETDHHKQIYRAH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCHHHHHHHHHH
FVEKGREAAKAALTIGKTRAALAA
HHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
TPTRYAFIKASWHADIVDRALDGFYQLVPPEQVDVFDVPGAFEMPLLSRDLAATGRYAA
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCHHHH
VVAAAFVVDGGIYRHEFVAQAVVDGLMRAGMDTGVPVLSVSLTPHQYQETDHHKQIYRAH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCHHHHHHHHHH
FVEKGREAAKAALTIGKTRAALAA
HHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8661681 [H]