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The map label for this gene is tpiA [H]

Identifier: 209549428

GI number: 209549428

Start: 1882398

End: 1883168

Strand: Reverse

Name: tpiA [H]

Synonym: Rleg2_1834

Alternate gene names: 209549428

Gene position: 1883168-1882398 (Counterclockwise)

Preceding gene: 209549429

Following gene: 209549427

Centisome position: 41.5

GC content: 65.5

Gene sequence:

>771_bases
ATGACACCTGACGTGCGCCCGCTCGTGGCGGGAAACTGGAAAATGAATGGCATGCGTGCCTCCCTGGATCAGATCAAGGC
GATCGCCGAGGGCGTTTCCTCGCCGCTCGCCGACAAGGTCGAAGCGCTGATCTGCCCGCCTGCGACGCTGCTCTACGTGG
CGACCGCGCTCTGCACCGACAGCCCGCTGTCGATCGGCGCTCAGGACTGCCATCAGAATCCGTCAGGTGCGCATACCGGC
GATATCTCGGCCGAGATGATTGCCGATTGTTTCGGCACCTATGTCATTGTCGGCCACTCCGAGCGCCGCACCGACCATGC
CGAAACGGATCATCTGGTCCGCGCCAAGGCGGAGGCTGCCTTTGCCGCCGGGCTGACGGCGATCATCTGCATCGGCGAGA
CGGCCGATGAACGCCGCACGGGCCAGGCGCTCGACGTCATCAAGCGTCAGCTTTCCGCCTCGGTTCCGGACAGCGCCGCC
GCCGAGAACACCGTCATCGCTTATGAACCGATCTGGGCGATCGGCACCGGTGTGACGCCGACGGCGGGCGATGTCGAAAA
GGCACACGCCTTCATGCGCGCCGAGCTGGTGGGCCGTTTCGGCGGTGAAGGCCGCAAGATGCGTCTTCTCTATGGCGGCT
CGGTCAAGCCGGCCAATGCCGGGGAGCTGATGGGCATCGCCAATGTCGACGGCGCGCTGATCGGCGGGGCGAGCTTGAAA
GCCGCCGACTTCCTCGCCATCTACCGGGCCTATGAGGCGCTGCTCGCCTGA

Upstream 100 bases:

>100_bases
GCGGGATCGCCGAGATTCCCCTTACGTCAAGGCATGATGCTTTTCTTTGCCGCGCGCTTTTGATATTGCCCAAGGCATAT
GGAAAATTTGGAAGGCTGGC

Downstream 100 bases:

>100_bases
GGCATTGTTCATTCCCGGTTTATTCGTTTATTCCAGGGCGTATTCTGGGCCGAAGGGCTTGGAATAGATGAAAGCCTCAT
GTAAAGAGCCGCCAGAATTC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM 1; Triose-phosphate isomerase 1 [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTPDVRPLVAGNWKMNGMRASLDQIKAIAEGVSSPLADKVEALICPPATLLYVATALCTDSPLSIGAQDCHQNPSGAHTG
DISAEMIADCFGTYVIVGHSERRTDHAETDHLVRAKAEAAFAAGLTAIICIGETADERRTGQALDVIKRQLSASVPDSAA
AENTVIAYEPIWAIGTGVTPTAGDVEKAHAFMRAELVGRFGGEGRKMRLLYGGSVKPANAGELMGIANVDGALIGGASLK
AADFLAIYRAYEALLA

Sequences:

>Translated_256_residues
MTPDVRPLVAGNWKMNGMRASLDQIKAIAEGVSSPLADKVEALICPPATLLYVATALCTDSPLSIGAQDCHQNPSGAHTG
DISAEMIADCFGTYVIVGHSERRTDHAETDHLVRAKAEAAFAAGLTAIICIGETADERRTGQALDVIKRQLSASVPDSAA
AENTVIAYEPIWAIGTGVTPTAGDVEKAHAFMRAELVGRFGGEGRKMRLLYGGSVKPANAGELMGIANVDGALIGGASLK
AADFLAIYRAYEALLA
>Mature_255_residues
TPDVRPLVAGNWKMNGMRASLDQIKAIAEGVSSPLADKVEALICPPATLLYVATALCTDSPLSIGAQDCHQNPSGAHTGD
ISAEMIADCFGTYVIVGHSERRTDHAETDHLVRAKAEAAFAAGLTAIICIGETADERRTGQALDVIKRQLSASVPDSAAA
ENTVIAYEPIWAIGTGVTPTAGDVEKAHAFMRAELVGRFGGEGRKMRLLYGGSVKPANAGELMGIANVDGALIGGASLKA
ADFLAIYRAYEALLA

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=253, Percent_Identity=37.9446640316205, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI226529917, Length=253, Percent_Identity=37.9446640316205, Blast_Score=164, Evalue=7e-41,
Organism=Escherichia coli, GI1790353, Length=250, Percent_Identity=40.8, Blast_Score=175, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17536593, Length=244, Percent_Identity=42.6229508196721, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320255, Length=235, Percent_Identity=41.7021276595745, Blast_Score=188, Evalue=9e-49,
Organism=Drosophila melanogaster, GI28572008, Length=247, Percent_Identity=42.914979757085, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI28572006, Length=247, Percent_Identity=42.914979757085, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI28572004, Length=247, Percent_Identity=42.914979757085, Blast_Score=174, Evalue=5e-44,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26692; Mature: 26560

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDVRPLVAGNWKMNGMRASLDQIKAIAEGVSSPLADKVEALICPPATLLYVATALCTD
CCCCCCCEEECCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCC
SPLSIGAQDCHQNPSGAHTGDISAEMIADCFGTYVIVGHSERRTDHAETDHLVRAKAEAA
CCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHH
FAAGLTAIICIGETADERRTGQALDVIKRQLSASVPDSAAAENTVIAYEPIWAIGTGVTP
HHHCCEEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHEECCCCCC
TAGDVEKAHAFMRAELVGRFGGEGRKMRLLYGGSVKPANAGELMGIANVDGALIGGASLK
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEECCCCHH
AADFLAIYRAYEALLA
HHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TPDVRPLVAGNWKMNGMRASLDQIKAIAEGVSSPLADKVEALICPPATLLYVATALCTD
CCCCCCEEECCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCC
SPLSIGAQDCHQNPSGAHTGDISAEMIADCFGTYVIVGHSERRTDHAETDHLVRAKAEAA
CCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHH
FAAGLTAIICIGETADERRTGQALDVIKRQLSASVPDSAAAENTVIAYEPIWAIGTGVTP
HHHCCEEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHEECCCCCC
TAGDVEKAHAFMRAELVGRFGGEGRKMRLLYGGSVKPANAGELMGIANVDGALIGGASLK
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEECCCCHH
AADFLAIYRAYEALLA
HHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA