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The map label for this gene is uxuA [H]

Identifier: 209549287

GI number: 209549287

Start: 1720352

End: 1721326

Strand: Reverse

Name: uxuA [H]

Synonym: Rleg2_1690

Alternate gene names: 209549287

Gene position: 1721326-1720352 (Counterclockwise)

Preceding gene: 209549288

Following gene: 209549286

Centisome position: 37.93

GC content: 60.92

Gene sequence:

>975_bases
ATGTATCTGGGAACACAGGTCGCCGCGCGGGATGACGACGATTATCGCATCTTCGCGCAACTGGGTGTGAAGCATATCAA
CGCCGATCCGCCGGGAGAACCGAGCAGCTGGACGCTTTCAGACCTCGAGCGCCATCGCGACAAGGTCGAAAGCTTCGGCC
TGATCCTCGACATGATCCAGCTGCCGCTGCCCTCGCAGCCGATCGAGAAGGCGTCCTATCCCGATATCCTGCTCGCCGGC
CCGGAGCGCGACAGGCAGATCGACGCCGTCTGCAAGCTGATCGAGAATACCGCAGCGGCCGGCATTCCGGCGGTGAAATA
CAATCTCAACCTCATCGGCATTCCCCGCACACCCGATGAGCCCGGACGCGGCGGCTCGATGAATGCCAGCTTCCGCTGGG
ACAAGACGGATCAGCAGGCCGCACCCGGTCTCGCCGGCGTTCTCTCCGAAGACGAAAACTGGGAACGGATCGACTATTTC
CTCGAACGCGTCGTGCCGGTCGCCGCAAGCAACCGCGTCAGGCTCGCCTGCCATCCGCATGATCCCTATACACCGCCCGG
CTTTCGCGGCGTCACGCGGGTGCTCGGCACCGTCGAAGGCCTGAAGAAGTTCGTGCTGATGCGCGAAAATCCCTATCACG
GCCTCAATTTCTGCCAGGGCTCGATCGGTGAAATGCTGGAAAATCCCGGCAAGGAGATCGACGACGTCATCCGCTGGTTC
GGTGAGCGCAACAAGATCTTCAATGTCCATTTCCGCAATATCCGCGGCGGCAAACTCTCCTTCATGGAGACCTTCCCCGA
CGAGGGCGACATGGACATGGTCCGCTCGGCCCGGATCTACAAGGAAGTGGGCTTCAAATACATGCTGATGCCCGACCATG
TGCCGACCGTCAGCGGTAAGGACCCTTCCGCCACCGCATTCGCCTATTGCTACGGCTATATCGCAGCCCTTCTGCAGACG
CTCGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
AACGTCGTTATCGGATGCTTTCCGAGCAGCAATAGGGCTCGACTCTCTTCAAAATTCATATTATGTCATATGACATTGTG
TAATTTCGAAAGAGACTCAA

Downstream 100 bases:

>100_bases
GACGGCCAATATCAACAGGTAAGGAACAGGACTTTCATGATGAACCCGATTGAATTGAAGAAGGCCGTCGGTAGTGGTCT
CCTCTCGTTTCCGGTGACGC

Product: Mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MYLGTQVAARDDDDYRIFAQLGVKHINADPPGEPSSWTLSDLERHRDKVESFGLILDMIQLPLPSQPIEKASYPDILLAG
PERDRQIDAVCKLIENTAAAGIPAVKYNLNLIGIPRTPDEPGRGGSMNASFRWDKTDQQAAPGLAGVLSEDENWERIDYF
LERVVPVAASNRVRLACHPHDPYTPPGFRGVTRVLGTVEGLKKFVLMRENPYHGLNFCQGSIGEMLENPGKEIDDVIRWF
GERNKIFNVHFRNIRGGKLSFMETFPDEGDMDMVRSARIYKEVGFKYMLMPDHVPTVSGKDPSATAFAYCYGYIAALLQT
LESA

Sequences:

>Translated_324_residues
MYLGTQVAARDDDDYRIFAQLGVKHINADPPGEPSSWTLSDLERHRDKVESFGLILDMIQLPLPSQPIEKASYPDILLAG
PERDRQIDAVCKLIENTAAAGIPAVKYNLNLIGIPRTPDEPGRGGSMNASFRWDKTDQQAAPGLAGVLSEDENWERIDYF
LERVVPVAASNRVRLACHPHDPYTPPGFRGVTRVLGTVEGLKKFVLMRENPYHGLNFCQGSIGEMLENPGKEIDDVIRWF
GERNKIFNVHFRNIRGGKLSFMETFPDEGDMDMVRSARIYKEVGFKYMLMPDHVPTVSGKDPSATAFAYCYGYIAALLQT
LESA
>Mature_324_residues
MYLGTQVAARDDDDYRIFAQLGVKHINADPPGEPSSWTLSDLERHRDKVESFGLILDMIQLPLPSQPIEKASYPDILLAG
PERDRQIDAVCKLIENTAAAGIPAVKYNLNLIGIPRTPDEPGRGGSMNASFRWDKTDQQAAPGLAGVLSEDENWERIDYF
LERVVPVAASNRVRLACHPHDPYTPPGFRGVTRVLGTVEGLKKFVLMRENPYHGLNFCQGSIGEMLENPGKEIDDVIRWF
GERNKIFNVHFRNIRGGKLSFMETFPDEGDMDMVRSARIYKEVGFKYMLMPDHVPTVSGKDPSATAFAYCYGYIAALLQT
LESA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 36250; Mature: 36250

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGTQVAARDDDDYRIFAQLGVKHINADPPGEPSSWTLSDLERHRDKVESFGLILDMIQ
CCCCCCEECCCCCCEEEHEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPLPSQPIEKASYPDILLAGPERDRQIDAVCKLIENTAAAGIPAVKYNLNLIGIPRTPDE
CCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC
PGRGGSMNASFRWDKTDQQAAPGLAGVLSEDENWERIDYFLERVVPVAASNRVRLACHPH
CCCCCCCCCCEEECCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
DPYTPPGFRGVTRVLGTVEGLKKFVLMRENPYHGLNFCQGSIGEMLENPGKEIDDVIRWF
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHH
GERNKIFNVHFRNIRGGKLSFMETFPDEGDMDMVRSARIYKEVGFKYMLMPDHVPTVSGK
CCCCCEEEEEEECCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
DPSATAFAYCYGYIAALLQTLESA
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYLGTQVAARDDDDYRIFAQLGVKHINADPPGEPSSWTLSDLERHRDKVESFGLILDMIQ
CCCCCCEECCCCCCEEEHEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPLPSQPIEKASYPDILLAGPERDRQIDAVCKLIENTAAAGIPAVKYNLNLIGIPRTPDE
CCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC
PGRGGSMNASFRWDKTDQQAAPGLAGVLSEDENWERIDYFLERVVPVAASNRVRLACHPH
CCCCCCCCCCEEECCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
DPYTPPGFRGVTRVLGTVEGLKKFVLMRENPYHGLNFCQGSIGEMLENPGKEIDDVIRWF
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHH
GERNKIFNVHFRNIRGGKLSFMETFPDEGDMDMVRSARIYKEVGFKYMLMPDHVPTVSGK
CCCCCEEEEEEECCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
DPSATAFAYCYGYIAALLQTLESA
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]