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The map label for this gene is gfo [H]

Identifier: 209549280

GI number: 209549280

Start: 1712477

End: 1713577

Strand: Reverse

Name: gfo [H]

Synonym: Rleg2_1683

Alternate gene names: 209549280

Gene position: 1713577-1712477 (Counterclockwise)

Preceding gene: 209549281

Following gene: 209549279

Centisome position: 37.76

GC content: 62.94

Gene sequence:

>1101_bases
ATGGAGAGAGTCGGTATCGGCATCATCGGATGCGGCAATATTTCGGGCGCCTATCTCACGGCGATGGCATCCTTTCCCAT
TCTCGACATTCGCGGCGTCGCCGATCTCAATCGGGAGCTGGCCGAGGCGAAAGCTAAGGAATTCAACGTTCCCGCCCGAT
CGATCGAAGAGCTTTTCGCCGATCCGAAGGTCGAGATCATCGTCAATCTGACGATCCCGAAAGCCCATGTGGCGGTCGCG
CTGCAGGCGCTCGAGGCCGGCAAACATACCTATTCGGAAAAGCCCCTCGGGATTAATTTCGCGGAAGGGAAAAAATTGGC
CGACGCCGCCAAGGCGAGGAATCTGCGCATCGGCGCGGCGCCCGACACCTTCCTCGGCGGCGGCCACCAGACGGCCCGCG
CGCTGATCGACCAGGGTGTCATCGGCCAGCCGGTCGGCGGCTCGGCGAGCTTCATGTGCCCCGGCCATGAACGCTGGCAT
CCGAATCCGGCTTTCTTCTACGAGGTCGGCGGGGGGCCGATGCTCGACATGGGTCCCTATTACATCACCGATCTCGTCAA
TCTTCTCGGGCCAGTTGCCGAGGTTGCGGGCTTTGCGACGACGCCGCGGACCGAACGGCTGATTACCAGCGAGCCGCGCA
ATGGCGAGCGGATCCCCGTCCATGTCCCCACCCATGTCGCCGGCATGATGCGTTTTGAGAACGGCGCCGTCGTCCAGATC
GCCATGAGCTTCGATGTCGCCGGCCACAAACATGTGCCGCTCGAAGTCTACGGCACCGAGGGCACGTTGATCGTGCCCGA
TCCCAACAAGTTCGCCGGCCCGGTGGAATATCTGAAGAAGGGCGGTCAGTTTGAGGACCAGCCGCTCACCGCACCCTATG
CCGACGGCAACTACCGCTCGCTCGGCGTCGCCGACATGGCGCATGCGATCCGCTCCAACCGTCCGCATCGGGCCAACGGC
GATCTGGCGCTGCATGTGCTCGAGGTCATGGAAGCGTTTCACACTGCGTCTGCGACAGGCCGGACGGTGGCGATATCAAC
GGCGGTGGAGCGCCCTGCCCCCTTGTCCCAATCGATCGTCGACGGACGGCTGGCGAAATAA

Upstream 100 bases:

>100_bases
CGCGGCTGCCGTGGCGCTATACGAGCTTTACGAATCGCCCTGGAGCACCACCGGGCCGGCGCTCTGACGGGCGCACAATC
ACGATCAGATGGAGGAATTC

Downstream 100 bases:

>100_bases
ATTCAGGAGGAAAGATTATGCGTGAAGCACTGATCGTCTGGGGTGGCTGGAGCGGGCACGAGCCGCAGGAATGCGCCGAA
ATCATCAAGACCATGCTCGA

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MERVGIGIIGCGNISGAYLTAMASFPILDIRGVADLNRELAEAKAKEFNVPARSIEELFADPKVEIIVNLTIPKAHVAVA
LQALEAGKHTYSEKPLGINFAEGKKLADAAKARNLRIGAAPDTFLGGGHQTARALIDQGVIGQPVGGSASFMCPGHERWH
PNPAFFYEVGGGPMLDMGPYYITDLVNLLGPVAEVAGFATTPRTERLITSEPRNGERIPVHVPTHVAGMMRFENGAVVQI
AMSFDVAGHKHVPLEVYGTEGTLIVPDPNKFAGPVEYLKKGGQFEDQPLTAPYADGNYRSLGVADMAHAIRSNRPHRANG
DLALHVLEVMEAFHTASATGRTVAISTAVERPAPLSQSIVDGRLAK

Sequences:

>Translated_366_residues
MERVGIGIIGCGNISGAYLTAMASFPILDIRGVADLNRELAEAKAKEFNVPARSIEELFADPKVEIIVNLTIPKAHVAVA
LQALEAGKHTYSEKPLGINFAEGKKLADAAKARNLRIGAAPDTFLGGGHQTARALIDQGVIGQPVGGSASFMCPGHERWH
PNPAFFYEVGGGPMLDMGPYYITDLVNLLGPVAEVAGFATTPRTERLITSEPRNGERIPVHVPTHVAGMMRFENGAVVQI
AMSFDVAGHKHVPLEVYGTEGTLIVPDPNKFAGPVEYLKKGGQFEDQPLTAPYADGNYRSLGVADMAHAIRSNRPHRANG
DLALHVLEVMEAFHTASATGRTVAISTAVERPAPLSQSIVDGRLAK
>Mature_366_residues
MERVGIGIIGCGNISGAYLTAMASFPILDIRGVADLNRELAEAKAKEFNVPARSIEELFADPKVEIIVNLTIPKAHVAVA
LQALEAGKHTYSEKPLGINFAEGKKLADAAKARNLRIGAAPDTFLGGGHQTARALIDQGVIGQPVGGSASFMCPGHERWH
PNPAFFYEVGGGPMLDMGPYYITDLVNLLGPVAEVAGFATTPRTERLITSEPRNGERIPVHVPTHVAGMMRFENGAVVQI
AMSFDVAGHKHVPLEVYGTEGTLIVPDPNKFAGPVEYLKKGGQFEDQPLTAPYADGNYRSLGVADMAHAIRSNRPHRANG
DLALHVLEVMEAFHTASATGRTVAISTAVERPAPLSQSIVDGRLAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=180, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581117, Length=313, Percent_Identity=25.5591054313099, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 39006; Mature: 39006

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVGIGIIGCGNISGAYLTAMASFPILDIRGVADLNRELAEAKAKEFNVPARSIEELFA
CCCEEEEEEEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHC
DPKVEIIVNLTIPKAHVAVALQALEAGKHTYSEKPLGINFAEGKKLADAAKARNLRIGAA
CCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHCCEEECCC
PDTFLGGGHQTARALIDQGVIGQPVGGSASFMCPGHERWHPNPAFFYEVGGGPMLDMGPY
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCEECCCCH
YITDLVNLLGPVAEVAGFATTPRTERLITSEPRNGERIPVHVPTHVAGMMRFENGAVVQI
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCHHHHHHEEECCCCEEEE
AMSFDVAGHKHVPLEVYGTEGTLIVPDPNKFAGPVEYLKKGGQFEDQPLTAPYADGNYRS
EEEEECCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
LGVADMAHAIRSNRPHRANGDLALHVLEVMEAFHTASATGRTVAISTAVERPAPLSQSIV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHH
DGRLAK
CCCCCC
>Mature Secondary Structure
MERVGIGIIGCGNISGAYLTAMASFPILDIRGVADLNRELAEAKAKEFNVPARSIEELFA
CCCEEEEEEEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHC
DPKVEIIVNLTIPKAHVAVALQALEAGKHTYSEKPLGINFAEGKKLADAAKARNLRIGAA
CCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHCCEEECCC
PDTFLGGGHQTARALIDQGVIGQPVGGSASFMCPGHERWHPNPAFFYEVGGGPMLDMGPY
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCEECCCCH
YITDLVNLLGPVAEVAGFATTPRTERLITSEPRNGERIPVHVPTHVAGMMRFENGAVVQI
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCHHHHHHEEECCCCEEEE
AMSFDVAGHKHVPLEVYGTEGTLIVPDPNKFAGPVEYLKKGGQFEDQPLTAPYADGNYRS
EEEEECCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
LGVADMAHAIRSNRPHRANGDLALHVLEVMEAFHTASATGRTVAISTAVERPAPLSQSIV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHH
DGRLAK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]