Click here to switch to the map view.

The map label for this gene is ccdA [H]

Identifier: 209549242

GI number: 209549242

Start: 1673814

End: 1674563

Strand: Reverse

Name: ccdA [H]

Synonym: Rleg2_1643

Alternate gene names: 209549242

Gene position: 1674563-1673814 (Counterclockwise)

Preceding gene: 209549243

Following gene: 209549241

Centisome position: 36.9

GC content: 64.67

Gene sequence:

>750_bases
GTGTCGATTGCTGATATTTCCCTGTGGAGCGCGTTGATTGCCGGGGCGCTTTCCTTTCTGTCGCCCTGCGTGCTTCCCCT
CGTCCCACCCTATCTCTGCTATATGGCCGGTATTTCAGTCGAGCAGTTCCGCGGCGGCGGCGCGGTTGCCATCGCCCCCG
ATATCAGGCGCGGCGTATTGTTCTCCGCTTTGCTCTTCACACTCGGCTTTGCCACTGTCTTCGTGGCGCTCGGCGCCGGC
GCCTCCAGCATCGGCATGGCGCTTCGCCAGCATCTCGACCTGTTGTCGAAGCTCGGCGGGCTGATCATCATCGTCATGGG
GCTGAATTTTCTCGGCCTCTTCCGGTTAGGGATTCTTGCCCGGGAGGCGCGCTTCCAGGGCGGCGGCAAGCCGGCGACGC
TGACGGGGGCCTATGTCATGGGCCTTGCCTTCGCCTTCGGCTGGACGCCCTGCATCGGGCCGGTGCTCGGCGCGATCCTT
GGCGTCGCCGCCTCGCGCGAGACGGTCGGTTCCGGCGCCGGGCTGCTTGCCGTCTATTCGCTCGGCCTGGCCATCCCCTT
CTGGATCGCCGCCGGCTTTTCCGGCGCCTTCATGCGCTTCCTGTCGCGCTTCCGCCGCCATCTCGGCACGGTGGAAAAGG
TGATGGGTGTCTTCCTCGTGCTGACCGGCCTCGCCTTCCTGTTCGGATGGGTCAGCAATGTGGCGATCTGGTTTCAGCAG
ACCTTCCCGATCCTGATGCAGATCGGCTAG

Upstream 100 bases:

>100_bases
CCCATTCATGGTTCAGGGCTCGCCAAACGCAAAAAGGTGATTGGCAATCCAGGTCCTGCAAAGCTAGGAACATCATGCAG
ATTGCAGCCGGAGAGAATGC

Downstream 100 bases:

>100_bases
ATCAAGCGCGGCCAGTCGATCGATCCGGTTGTTCGACGCCCCGGCAACCTGAATGACAAGACCTATGCGGTGGTATAGCT
CGCCCTGTCCTTGGCCCCAC

Product: cytochrome C biogenesis protein transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSIADISLWSALIAGALSFLSPCVLPLVPPYLCYMAGISVEQFRGGGAVAIAPDIRRGVLFSALLFTLGFATVFVALGAG
ASSIGMALRQHLDLLSKLGGLIIIVMGLNFLGLFRLGILAREARFQGGGKPATLTGAYVMGLAFAFGWTPCIGPVLGAIL
GVAASRETVGSGAGLLAVYSLGLAIPFWIAAGFSGAFMRFLSRFRRHLGTVEKVMGVFLVLTGLAFLFGWVSNVAIWFQQ
TFPILMQIG

Sequences:

>Translated_249_residues
MSIADISLWSALIAGALSFLSPCVLPLVPPYLCYMAGISVEQFRGGGAVAIAPDIRRGVLFSALLFTLGFATVFVALGAG
ASSIGMALRQHLDLLSKLGGLIIIVMGLNFLGLFRLGILAREARFQGGGKPATLTGAYVMGLAFAFGWTPCIGPVLGAIL
GVAASRETVGSGAGLLAVYSLGLAIPFWIAAGFSGAFMRFLSRFRRHLGTVEKVMGVFLVLTGLAFLFGWVSNVAIWFQQ
TFPILMQIG
>Mature_248_residues
SIADISLWSALIAGALSFLSPCVLPLVPPYLCYMAGISVEQFRGGGAVAIAPDIRRGVLFSALLFTLGFATVFVALGAGA
SSIGMALRQHLDLLSKLGGLIIIVMGLNFLGLFRLGILAREARFQGGGKPATLTGAYVMGLAFAFGWTPCIGPVLGAILG
VAASRETVGSGAGLLAVYSLGLAIPFWIAAGFSGAFMRFLSRFRRHLGTVEKVMGVFLVLTGLAFLFGWVSNVAIWFQQT
FPILMQIG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26139; Mature: 26007

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCC
>Mature Secondary Structure 
SIADISLWSALIAGALSFLSPCVLPLVPPYLCYMAGISVEQFRGGGAVAIAPDIRRGVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECCHHHHHHH
FSALLFTLGFATVFVALGAGASSIGMALRQHLDLLSKLGGLIIIVMGLNFLGLFRLGILA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REARFQGGGKPATLTGAYVMGLAFAFGWTPCIGPVLGAILGVAASRETVGSGAGLLAVYS
HHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGLAIPFWIAAGFSGAFMRFLSRFRRHLGTVEKVMGVFLVLTGLAFLFGWVSNVAIWFQQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFPILMQIG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]