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The map label for this gene is algE1 [H]

Identifier: 209549153

GI number: 209549153

Start: 1578924

End: 1580957

Strand: Reverse

Name: algE1 [H]

Synonym: Rleg2_1554

Alternate gene names: 209549153

Gene position: 1580957-1578924 (Counterclockwise)

Preceding gene: 209549154

Following gene: 209549151

Centisome position: 34.84

GC content: 60.52

Gene sequence:

>2034_bases
ATGACAACATACTACGTAGCGACGACTGGCAGCGACAGCGGTAACGGCAGTGCCTCTTCTCCTTTCCGCACGATCAGTGA
CGCGATGGCGTCGAACCTTAAGCCCGGCGACGAGGTCGTGGTTAAAGCGGGGACCTACAACGAGAGCATTAATTTCGACA
AGGACGGCTCGGCGGCAGGCAACATCACGCTGCGCTCGGAAGTTCCCGGCGCAGCACTGATCCGGCCGCCCGCGGGCTCC
TACACCGGGATCAGTGTCAACGCCAATTACGTTGTCATCAACGGCTTCGACATCAAGGGCGGCAACGGCGACGGCATCGA
AGCGAACAACGTCCACCATGTCCAGATCCTCAACAACACGGTCCACGACAGCGGCGAGTCGGGCATCCAGTTCAACCAAT
CGGACTTCATCCGCATCGAGGGGAACGAGACCTACAATAACGCGTCGTCGGGCTGGTTCTCGGGCATCTCGATCTACGAG
AACCGGAACATTACAGGCGATACCTCGACGGACGGCTACCGGACGATCGTGCGGAACAACGTCTCGCACGACAACGTCAC
GAAGTCGGGTGCGCACACCGATGGCAACGGCATCATCATCGACGATTTCCAGAGCACGCAAACGAGCGGTCATCCGAACT
ACACATTCAAGACCCTGGTCGACAACAACCTCGTCTACGACAACGGCGGCAAAGGCATCCAAGTTGCCTGGAGCGACTCC
GTCACAGTGCAGAACAACACCGCATACCACAACAATCAGGATCCGCTAAACGACGGAACCTGGCGCGGCGAGCTCAGCAA
CGCGCAGTCGAGCAACAACACCTGGGTCAACAACGTCGCCGTAGCGGATCCGTCGGTGAACAAGAACAACACTGCAGTCG
ATAACACGTCGTACGGCGGCTACAGCAACAACAACGTCGTCTGGGCCAACAACCTCACCTACAACGGCACGGCCGGCCAG
GCATCGGTCAAGACCGACGGCGGCAACGCGATGCCGAGCGCGGCGAACGGCAACAAACTCGGCGTCGACCCGAAATTCGC
AGGCGCAGCAAGCGACAACTTCCACCTCGGCTCTGGCTCGTCGGCGATCGACGGCGGAACCAGCAAGTACGGCGTCGGCT
CGGTCGATCTGGACGGCCACGCTCGCGTCGTTGGAACTGTCGATATGGGTGCCTACGAATCGGGCTCCACCTCGACACCG
ACAACGCCAACCACGCCGACCACGCCGACCGAACCAGGTTCGGGAACGCCGACCACGCCAACTCAACCGACAACGCCAAC
CGCGCCGACGAAGGAAATCGTGGGCACTAGCGGCAACGATATCCTGCCACACACGGGTCAGTCGAACGGCGGCAACGAAA
CCTTCAAGGGTCTCGGTGGTAGTGATGTGTTGAAGGGCGGGGCCGGCGCGGATGCGCTCGACGGCGGTACTGGCAACGAC
ACCGCCAGCTATGCGGGCTCCGGCGCGGTCAACGTCAACTTGGCGACTAAGGTCGCATCGGGCGGCGATGCGACCGGCGA
CAAGATCGCCAGTATCGAAAACTTGACCGGCTCAAGCTACAACGACGTACTGACCGGCGGCAACGGCGGCGGCAACGTTC
TCACTGGCGGGGCTGGCGCGGACAAGCTGGACGGCGGCGCCGGCAATGATGTCCTCATTGGTGGTTCCGGAAAGGACATT
ATGACCGGTGGCACCGGCGAGGATAAGTTTATCTTGAAAGCACCGACGGAAACCGGGTCCGGCTTGAACCGCGACGTCAT
CACCGACTTCCAGCACGGCATCGATAAGATCGACCTCTCGGCGATCGATGCGAACGGCTCTGCGGCGGGCAATGGAACCT
TCCATTTTCAGGCACAGGAGAATGCCTTGTTCGACCACAAGGCTGGCGCGCTCGCTTGGCACTATGACGACCAGTCCGGA
ACCGCGAACGATGTTACCGTTATCCAGGCCGACACGAACGGCGACGGTGTTCATGACTTCGAGGTTCAGCTGAAGGGCTT
GGTCCACTTAGGGGCAGGCGATTTTCTCCTGTAA

Upstream 100 bases:

>100_bases
CGCGTTGCTGTTGCGCCCTCCAAAATGTCGCCCTATAACCCCCCGCCGTAAGACATGATTAACCTAAAATATTAACGGGC
AGGGGTTGAGGAACAAGACA

Downstream 100 bases:

>100_bases
TTGTCCCCGTTGTGGCGGTCGTCCGATCGCCACAACCATCGTGCTGACATCCGAGCGCCGATCAGGCGTTCGGACACCAA
GGTCTCCATCATCGTCGACG

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: Mannuronan epimerase 1 [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MTTYYVATTGSDSGNGSASSPFRTISDAMASNLKPGDEVVVKAGTYNESINFDKDGSAAGNITLRSEVPGAALIRPPAGS
YTGISVNANYVVINGFDIKGGNGDGIEANNVHHVQILNNTVHDSGESGIQFNQSDFIRIEGNETYNNASSGWFSGISIYE
NRNITGDTSTDGYRTIVRNNVSHDNVTKSGAHTDGNGIIIDDFQSTQTSGHPNYTFKTLVDNNLVYDNGGKGIQVAWSDS
VTVQNNTAYHNNQDPLNDGTWRGELSNAQSSNNTWVNNVAVADPSVNKNNTAVDNTSYGGYSNNNVVWANNLTYNGTAGQ
ASVKTDGGNAMPSAANGNKLGVDPKFAGAASDNFHLGSGSSAIDGGTSKYGVGSVDLDGHARVVGTVDMGAYESGSTSTP
TTPTTPTTPTEPGSGTPTTPTQPTTPTAPTKEIVGTSGNDILPHTGQSNGGNETFKGLGGSDVLKGGAGADALDGGTGND
TASYAGSGAVNVNLATKVASGGDATGDKIASIENLTGSSYNDVLTGGNGGGNVLTGGAGADKLDGGAGNDVLIGGSGKDI
MTGGTGEDKFILKAPTETGSGLNRDVITDFQHGIDKIDLSAIDANGSAAGNGTFHFQAQENALFDHKAGALAWHYDDQSG
TANDVTVIQADTNGDGVHDFEVQLKGLVHLGAGDFLL

Sequences:

>Translated_677_residues
MTTYYVATTGSDSGNGSASSPFRTISDAMASNLKPGDEVVVKAGTYNESINFDKDGSAAGNITLRSEVPGAALIRPPAGS
YTGISVNANYVVINGFDIKGGNGDGIEANNVHHVQILNNTVHDSGESGIQFNQSDFIRIEGNETYNNASSGWFSGISIYE
NRNITGDTSTDGYRTIVRNNVSHDNVTKSGAHTDGNGIIIDDFQSTQTSGHPNYTFKTLVDNNLVYDNGGKGIQVAWSDS
VTVQNNTAYHNNQDPLNDGTWRGELSNAQSSNNTWVNNVAVADPSVNKNNTAVDNTSYGGYSNNNVVWANNLTYNGTAGQ
ASVKTDGGNAMPSAANGNKLGVDPKFAGAASDNFHLGSGSSAIDGGTSKYGVGSVDLDGHARVVGTVDMGAYESGSTSTP
TTPTTPTTPTEPGSGTPTTPTQPTTPTAPTKEIVGTSGNDILPHTGQSNGGNETFKGLGGSDVLKGGAGADALDGGTGND
TASYAGSGAVNVNLATKVASGGDATGDKIASIENLTGSSYNDVLTGGNGGGNVLTGGAGADKLDGGAGNDVLIGGSGKDI
MTGGTGEDKFILKAPTETGSGLNRDVITDFQHGIDKIDLSAIDANGSAAGNGTFHFQAQENALFDHKAGALAWHYDDQSG
TANDVTVIQADTNGDGVHDFEVQLKGLVHLGAGDFLL
>Mature_676_residues
TTYYVATTGSDSGNGSASSPFRTISDAMASNLKPGDEVVVKAGTYNESINFDKDGSAAGNITLRSEVPGAALIRPPAGSY
TGISVNANYVVINGFDIKGGNGDGIEANNVHHVQILNNTVHDSGESGIQFNQSDFIRIEGNETYNNASSGWFSGISIYEN
RNITGDTSTDGYRTIVRNNVSHDNVTKSGAHTDGNGIIIDDFQSTQTSGHPNYTFKTLVDNNLVYDNGGKGIQVAWSDSV
TVQNNTAYHNNQDPLNDGTWRGELSNAQSSNNTWVNNVAVADPSVNKNNTAVDNTSYGGYSNNNVVWANNLTYNGTAGQA
SVKTDGGNAMPSAANGNKLGVDPKFAGAASDNFHLGSGSSAIDGGTSKYGVGSVDLDGHARVVGTVDMGAYESGSTSTPT
TPTTPTTPTEPGSGTPTTPTQPTTPTAPTKEIVGTSGNDILPHTGQSNGGNETFKGLGGSDVLKGGAGADALDGGTGNDT
ASYAGSGAVNVNLATKVASGGDATGDKIASIENLTGSSYNDVLTGGNGGGNVLTGGAGADKLDGGAGNDVLIGGSGKDIM
TGGTGEDKFILKAPTETGSGLNRDVITDFQHGIDKIDLSAIDANGSAAGNGTFHFQAQENALFDHKAGALAWHYDDQSGT
ANDVTVIQADTNGDGVHDFEVQLKGLVHLGAGDFLL

Specific function: Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted, extracellular space. Note=Probably exported via the hemolysin-type secretion pathway [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 15 PbH1 repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006633
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR022441
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 69082; Mature: 68950

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYYVATTGSDSGNGSASSPFRTISDAMASNLKPGDEVVVKAGTYNESINFDKDGSAAG
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCC
NITLRSEVPGAALIRPPAGSYTGISVNANYVVINGFDIKGGNGDGIEANNVHHVQILNNT
CEEEECCCCCCEEEECCCCCEEEEEEECCEEEEEEEEECCCCCCCCCCCCEEEEEEECCC
VHDSGESGIQFNQSDFIRIEGNETYNNASSGWFSGISIYENRNITGDTSTDGYRTIVRNN
CCCCCCCCEEECCCCEEEEECCCCCCCCCCCEECCEEEEECCCCCCCCCCCCEEHHHHCC
VSHDNVTKSGAHTDGNGIIIDDFQSTQTSGHPNYTFKTLVDNNLVYDNGGKGIQVAWSDS
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCEEEECCCCEEEEEECCC
VTVQNNTAYHNNQDPLNDGTWRGELSNAQSSNNTWVNNVAVADPSVNKNNTAVDNTSYGG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
YSNNNVVWANNLTYNGTAGQASVKTDGGNAMPSAANGNKLGVDPKFAGAASDNFHLGSGS
CCCCCEEEECCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
SAIDGGTSKYGVGSVDLDGHARVVGTVDMGAYESGSTSTPTTPTTPTTPTEPGSGTPTTP
CCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQPTTPTAPTKEIVGTSGNDILPHTGQSNGGNETFKGLGGSDVLKGGAGADALDGGTGND
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCCCCCCCCCCCCCCCC
TASYAGSGAVNVNLATKVASGGDATGDKIASIENLTGSSYNDVLTGGNGGGNVLTGGAGA
CHHCCCCCEEEEEEEEEECCCCCCCCCHHEEEHHCCCCCCCCEEECCCCCCCEEECCCCC
DKLDGGAGNDVLIGGSGKDIMTGGTGEDKFILKAPTETGSGLNRDVITDFQHGIDKIDLS
CCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEE
AIDANGSAAGNGTFHFQAQENALFDHKAGALAWHYDDQSGTANDVTVIQADTNGDGVHDF
EECCCCCCCCCCEEEEEECCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCEEEE
EVQLKGLVHLGAGDFLL
EEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TTYYVATTGSDSGNGSASSPFRTISDAMASNLKPGDEVVVKAGTYNESINFDKDGSAAG
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCC
NITLRSEVPGAALIRPPAGSYTGISVNANYVVINGFDIKGGNGDGIEANNVHHVQILNNT
CEEEECCCCCCEEEECCCCCEEEEEEECCEEEEEEEEECCCCCCCCCCCCEEEEEEECCC
VHDSGESGIQFNQSDFIRIEGNETYNNASSGWFSGISIYENRNITGDTSTDGYRTIVRNN
CCCCCCCCEEECCCCEEEEECCCCCCCCCCCEECCEEEEECCCCCCCCCCCCEEHHHHCC
VSHDNVTKSGAHTDGNGIIIDDFQSTQTSGHPNYTFKTLVDNNLVYDNGGKGIQVAWSDS
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCEEEECCCCEEEEEECCC
VTVQNNTAYHNNQDPLNDGTWRGELSNAQSSNNTWVNNVAVADPSVNKNNTAVDNTSYGG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
YSNNNVVWANNLTYNGTAGQASVKTDGGNAMPSAANGNKLGVDPKFAGAASDNFHLGSGS
CCCCCEEEECCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
SAIDGGTSKYGVGSVDLDGHARVVGTVDMGAYESGSTSTPTTPTTPTTPTEPGSGTPTTP
CCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQPTTPTAPTKEIVGTSGNDILPHTGQSNGGNETFKGLGGSDVLKGGAGADALDGGTGND
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCCCCCCCCCCCCCCCC
TASYAGSGAVNVNLATKVASGGDATGDKIASIENLTGSSYNDVLTGGNGGGNVLTGGAGA
CHHCCCCCEEEEEEEEEECCCCCCCCCHHEEEHHCCCCCCCCEEECCCCCCCEEECCCCC
DKLDGGAGNDVLIGGSGKDIMTGGTGEDKFILKAPTETGSGLNRDVITDFQHGIDKIDLS
CCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEE
AIDANGSAAGNGTFHFQAQENALFDHKAGALAWHYDDQSGTANDVTVIQADTNGDGVHDF
EECCCCCCCCCCEEEEEECCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCEEEE
EVQLKGLVHLGAGDFLL
EEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7476166; 9812987; 10322003; 11243259; 10937941 [H]