| Definition | Escherichia coli O157:H7 str. EC4115, complete genome. |
|---|---|
| Accession | NC_011353 |
| Length | 5,572,075 |
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The map label for this gene is gcd [H]
Identifier: 209400840
GI number: 209400840
Start: 143188
End: 145578
Strand: Reverse
Name: gcd [H]
Synonym: ECH74115_0132
Alternate gene names: 209400840
Gene position: 145578-143188 (Counterclockwise)
Preceding gene: 209399514
Following gene: 209396813
Centisome position: 2.61
GC content: 55.21
Gene sequence:
>2391_bases ATGGCAATTAACAATACAGGCTCGCGACGATTACTCGTCACGCTAACAGCCCTTTTTGCAGCGCTTTGCGGGCTGTATCT ACTCATTGGCGGAGGCTGGCTGGTCGCGATTGGCGGCTCCTGGTACTACCCTATCGCTGGCCTTGTGATGCTCGGCGTCG CCTGGATGCTGTGGCGCAGTAAACGTGCCGCGCTTTGGCTATACGCCGCCCTGCTGCTCGGCACCATGATTTGGGGCGTC TGGGAAGTTGGTTTCGACTTCTGGGCGCTGACTCCGCGCAGCGATATTCTGGTCTTCTTCGGCATCTGGCTGATCCTGCC GTTTGTCTGGCGTCGCCTGGTCATTCCTGCCAGCGGCGCAGTTGCCGCACTGGTGGTGGCACTGCTGATTAGCGGTAGTA TCCTGACCTGGGCCGGATTTAACGATCCGCAGGAAATCAACGGCACCTTAAGCGCCGATGCCACACCTGCGGAAGCTATC TCACCCGTTGCCGATCAGGACTGGCCTGCCTATGGTCGCAATCAGGAAGGTCAACGCTTTTCACCTCTGAAACAAATTAA CGCCGATAACGTCCATAATCTGAAAGAAGCCTGGGTGTTCCGTACTGGCGATGTGAAGCAGCCGAACGATCCGGGCGAAA TCACCAATGAAGTGACGCCGATTAAAGTGGGCGACACCCTTTACCTGTGTACCGCTCACCAGCGCCTGTTTGCGCTCGAT GCCGCCAGCGGCAAAGAGAAATGGCATTACGATCCTGAGCTGAAAACTAACGAGTCTTTCCAGCACGTAACCTGCCGTGG CGTCTCTTATCATGAAGCCAAAGCAGAAACGGCTTCGCCGGAAGTGATGGCGGATTGCCCGCGTCGTATCATTCTTCCGG TCAATGATGGTCGCCTGATTGCGATTAACGCTGAAAACGGCAAGCTGTGCGAAACCTTCGCCAATAAAGGCGTGCTCAAT CTGCAAAGCAATATGCCAGACACCAAACCGGGTCTGTATGAACCGACTTCGCCACCGATTATCACCGATAAAACCATCGT GATGGCAGGTTCAGTTACCGATAACTTCTCAACCCGCGAAACGTCTGGCGTGATCCGTGGTTTTGATGTCAACACCGGGG AGCTGCTGTGGGCTTTTGATCCGGGCGCGAAAGATCCGAACGCAATCCCGTCTGACGAACACACCTTTACCTTTAACTCG CCAAACTCGTGGGCACCAGCGGCCTATGACGCGAAGCTGGATCTGGTGTATCTGCCGATGGGCGTGACCACGCCGGATAT CTGGGGCGGTAACCGCACACCGGAACAGGAACGTTATGCCAGCTCGATTCTGGCGCTGAATGCCACAACCGGGAAATTGG CGTGGAGCTACCAGACCGTTCACCACGACCTGTGGGATATGGATCTTCCGGCACAGCCGACGCTGGCGGACATCACCGTT AATGGTCAGAAAGTGCCAGTTATTTACGCTCCGGCGAAAACCGGCAACATTTTTGTGCTCGATCGTCGTAATGGCGAACT GGTGGTTCCGGCACCGGAAAAACCGGTTCCCCAAGGTGCTGCCAAAGGCGATTACGTTACCCCTACTCAACCATTCTCGG AACTGAGCTTCCGTCCGACGAAAGATTTGAGCGGTGCGGATATGTGGGGAGCCACCATGTTTGACCAACTGGTGTGCCGC GTGATGTTCCACCAGATGCGCTATGAAGGCATTTTCACGCCGCCATCTGAACAGGGCACGCTGGTCTTCCCGGGTAACCT GGGAATGTTTGAATGGGGCGGGATTTCCGTTGATCCAAATCGTGAAGTGGCAATTGCCAACCCAATGGCACTGCCGTTTG TTTCGAAACTGATCCCACGCGGTCCGGGTAACCCGATGGAGCAGCCGAAAGATGCCAAAGGCACGGGTACGGAATCCGGC ATTCAGCCACAGTACGGTGTACCGTATGGTGTCACGCTCAACCCGTTCCTCTCACCATTTGGTCTGCCATGTAAACAGCC AGCATGGGGTTATATCTCGGCGCTGGATCTGAAAACTAATGAAGTGGTGTGGAAGAAACGTATTGGTACGCCGCAGGACA GTATGCCGTTCCCGATGCCTGTACCGGTGCCGTTCAATATGGGTATGCCGATGCTGGGCGGGCCAATCTCCACGGCGGGT AACGTGCTGTTTATCGCCGCTACGGCAGATAACTACCTGCGCGCTTACAACATGAGCAACGGTGAAAAACTGTGGCAGGG TCGTTTACCAGCGGGTGGTCAGGCGACGCCAATGACCTATGAAGTGAATGGTAAGCAGTATGTGGTGATCTCCGCAGGCG GTCACGGTTCATTTGGTACGAAGATGGGTGACTATATTGTGGCTTATGCGCTGCCGGATGATGTGAAGTAA
Upstream 100 bases:
>100_bases GAATCTGTTAATAAAGCTCAAATTGTGATGACGATCACACATGTTAAAACCTATAATTAATTGCTACTAAAATATTAATG AATTGAAATGGTGTCTCTTT
Downstream 100 bases:
>100_bases GACTTGCTCAGATTGCTGACAACGTGCGCGTTGTTCATGCCGGATGCGGCGTGAACGCCTTATCCAGCCTACAAAATTGT GCAAAATCAATGGATTGCAC
Product: quinoprotein glucose dehydrogenase
Products: NA
Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]
Number of amino acids: Translated: 796; Mature: 795
Protein sequence:
>796_residues MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Sequences:
>Translated_796_residues MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK >Mature_795_residues AINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVW EVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAIS PVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDA ASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNL QSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSP NSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVN GQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRV MFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGI QPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGN VLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]
COG id: COG4993
COG function: function code G; Glucose dehydrogenase
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]
Homologues:
Organism=Escherichia coli, GI1786316, Length=796, Percent_Identity=99.8743718592965, Blast_Score=1629, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017511 - InterPro: IPR019556 - InterPro: IPR019551 - InterPro: IPR018391 - InterPro: IPR002372 - InterPro: IPR011047 - InterPro: IPR001479 [H]
Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]
EC number: =1.1.5.2 [H]
Molecular weight: Translated: 86778; Mature: 86647
Theoretical pI: Translated: 5.29; Mature: 5.29
Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRS CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEEECCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHCCCCCHHHHHHHEEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPT CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC >Mature Secondary Structure AINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRS CCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEEECCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHCCCCCHHHHHHHEEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPT CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]