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The map label for this gene is fsaB

Identifier: 209400568

GI number: 209400568

Start: 5049041

End: 5049703

Strand: Reverse

Name: fsaB

Synonym: ECH74115_5407

Alternate gene names: 209400568

Gene position: 5049703-5049041 (Counterclockwise)

Preceding gene: 209399874

Following gene: 209396171

Centisome position: 90.63

GC content: 53.7

Gene sequence:

>663_bases
ATGGAACTGTATCTGGACACCGCTAACGTCGCAGAAGTCGAACGTCTGGCACACATATTCCCGATTGCCGGGGTGACAAC
TAACCCGAGCATTATCGCTGCCAGCAAGGAGTCCATATGGGAAGTGCTGCCGCGTCTGCAAAAAGCGATTGGTGATGAGG
GCATTCTGTTTGCTCAGACCATGAGCCGCGACGCGCAGGGGATGGTGGAAGAAGCGAAGCGTCTGCGCGATGCCATTCCG
GGCATTGTGGTGAAAATCCCGGTGACTTCCGAAGGTCTGGCAGCAATTAAAATACTGAAAAAAGAGGGTATTACTACACT
TGGCACTGCTGTATATAGCGCCGCACAAGGGTTATTAGCCGCACTGGCAGGGGCAAAATACGTTGCTCCGTATGTTAACC
GCGTGGATGCCCAGGGCGGGGACGGCATTCGTACGGTTCAGGAGCTGCAAGCGCTGTTAGAAATGCACGCACCAGAAAGC
ATGGTGCTGGCGGCCAGCTTTAAAACGCCGCGTCAGGCGCTGGACTGTTTACTGGCAGGATGTGAATCCATCACCCTGCC
CTTAGATGTAGCGCAACAAATGCTCAACACCCCTGCGGTAGAGTCAGCTATAGAGAAGTTCGAACACGACTGGAATGCCG
CATTTGGCACTACTCATCTCTAA

Upstream 100 bases:

>100_bases
TCATGCACGAAGAATTCCGTAACGCGCTGGTTAACGCCGCCTCTGCCGACGCTATCGCCAGCCTGCTGCAACATGAACTG
GAACTGTAAAAGGAAACATC

Downstream 100 bases:

>100_bases
AGGAGCAATTATGGACCGCATTATTCAATCACCGGGTAAATACATCCAGGGCGCTGATGTGATTAATCGTCTGGGCGAAT
ACCTGAAGCCGCTGGCAGAA

Product: fructose-6-phosphate aldolase

Products: dihydroxy-acetone; glyceraldehyde-3-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIP
GIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL

Sequences:

>Translated_220_residues
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIP
GIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL
>Mature_220_residues
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIP
GIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL

Specific function: Fructose-6-phosphate Aldolase Activity [C]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3A subfamily

Homologues:

Organism=Escherichia coli, GI1790382, Length=220, Percent_Identity=99.0909090909091, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI87081788, Length=220, Percent_Identity=69.5454545454545, Blast_Score=315, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FSAB_ECO57 (P58424)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C91238
- PIR:   G86085
- RefSeq:   NP_290583.1
- RefSeq:   NP_312902.1
- ProteinModelPortal:   P58424
- SMR:   P58424
- EnsemblBacteria:   EBESCT00000024711
- EnsemblBacteria:   EBESCT00000055471
- GeneID:   915012
- GeneID:   960185
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5501
- KEGG:   ecs:ECs4875
- GeneTree:   EBGT00050000009452
- HOGENOM:   HBG533000
- OMA:   DWNNAFG
- ProtClustDB:   PRK12655
- BioCyc:   ECOL83334:ECS4875-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00496
- InterPro:   IPR013785
- InterPro:   IPR023001
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: 2.2.1.- [C]

Molecular weight: Translated: 23506; Mature: 23506

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQT
CEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEEHHH
MSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLA
HCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPESMVLAASFKTPRQALDCLLAG
HHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
CESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL
HCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQT
CEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEEHHH
MSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLA
HCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPESMVLAASFKTPRQALDCLLAG
HHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
CESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL
HCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fructose-6-phosphate [C]

Specific reaction: fructose-6-phosphate = dihydroxy-acetone + glyceraldehyde-3-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796