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The map label for this gene is mocR [H]

Identifier: 209400513

GI number: 209400513

Start: 3627047

End: 3628381

Strand: Reverse

Name: mocR [H]

Synonym: ECH74115_3915

Alternate gene names: 209400513

Gene position: 3628381-3627047 (Counterclockwise)

Preceding gene: 209399778

Following gene: 209398919

Centisome position: 65.12

GC content: 53.78

Gene sequence:

>1335_bases
ATGCCACGTTATCAGGATATCGCCCGTCAGTTAAAAACGGTTATCGAGCAAGGAAAACTGAAACCTGGCGCAAGGCTACC
TTCGAGCCGTACCTGGTCGCAGGAGCTGGGTGTCTCTCGATCCACTGTCGAAAATGCTTATGCTGAGCTGGTGGCGCAGG
GATGGCTGGTCAGGCGGGGACAGGCGGGTACCTTTGTCAGTGAGCAGATACATCCGCAACAGTCTGCTGTGGATGTCGTG
GCTTTTGCTGGTGAAAGTCAGCAGCCGCTGCCTTTTCAGATGGGGCTACCTGCACTTGATCTTTTTCCGCGTGAATTGTG
GGCGCGGGTGATGGGCCGCCGTCTGCGTACCCAGACGCGCTTTGATTTGGCATTAGGCGATGTCTGCGGCGAGGCGGCCT
TGCGCGAGGCTATTGTTGATTATTTACGCGTTTCACGTGGGATTGATTGTCAGCCAGAGCAGGTCTTTATCACTCACGGT
TATGCGGCCTCAATGGCTTTAATTCTGCACGCTCTGGCGCAACCGGGAGACGGGATGTGGATGGAAGATCCCGGCTTTCC
GCTGATTCGCCCGATTGTCACTCGCCACGGTGTGGAAATTTTACCTGTGCCGGTTGATGACAACGGACTGGATGTCACAA
GCGGAATACAAAATTATCCTGATGCGCGTTTTGCCCTGATTACTCCGGCACACCAAAGCCCGCTGGGTGTGGCACTCTCT
TTAGCGCGTAGGTATCAGATACTGGAATGGGCAGAGCGTAGTCAGGCATGGATTATTGAAGATGATTACGACAGTGAGTT
TCGCTATCACGGTAAGCCGTTACCGGCACTAAAAAGTCTCGACGCGCCGCAGCGGGTGATTTATGCCGGAACATTCAGCA
AAGCGCTATTTCCTGCATTGCGCTGTGCGTGGCTGGTGGTGCCGGTGGAGCAGATTTCGCAATTCCGGCAGCAGGCGTCA
CTGGAACCATGTGCTGTACCCGTACTGTGGCAGAACACACTGGCAGATTTCATCCGTGAGGGGCATTTCTGGCGGCATCT
GAAGAAAATGCGCCAGCATTATGCCCAGCGACGGCAGTGGATTGAGCAGGCACTTACGCAGCAGGGATTTCAGGTTGTGC
CGCAAAAAGGCGGTATCCAGATGGTGATCAAACTAGCAGGTAATGACGTGACATTCGTGCATAAAGCCAATGCTGCTGGT
CTTGCCGTACAGGCACTTAGCGACTGGCGTATCCGCTCAAGCGAGGACGGAGGATTATTGCTCTCGTTTACGAATATCGT
TAGCGAAAGTATGGCGCGACAGGTAGCACAGCAATTGCGCAGTGCTTTAAATTAA

Upstream 100 bases:

>100_bases
GTAATGTAGTCATACAGTTTCTCCTCTTATTAACGCCCGCAATGTAGCACTATAATGGACTGCTAAAGAGAGCCATAAAT
TACCTAAAAAAGCAGACCAT

Downstream 100 bases:

>100_bases
TAACCCCGAAGCCAGGCTTCGGGGTCCTATAAGACTGGTGACCAGGGCAAAATCCCCTGATGCGCTATGTTTTTCAGGCC
TGTAGGCGGACAAGGCGTTG

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MPRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRGQAGTFVSEQIHPQQSAVDVV
AFAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTRFDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHG
YAASMALILHALAQPGDGMWMEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALS
LARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPALRCAWLVVPVEQISQFRQQAS
LEPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQWIEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAG
LAVQALSDWRIRSSEDGGLLLSFTNIVSESMARQVAQQLRSALN

Sequences:

>Translated_444_residues
MPRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRGQAGTFVSEQIHPQQSAVDVV
AFAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTRFDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHG
YAASMALILHALAQPGDGMWMEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALS
LARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPALRCAWLVVPVEQISQFRQQAS
LEPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQWIEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAG
LAVQALSDWRIRSSEDGGLLLSFTNIVSESMARQVAQQLRSALN
>Mature_443_residues
PRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRGQAGTFVSEQIHPQQSAVDVVA
FAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTRFDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHGY
AASMALILHALAQPGDGMWMEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALSL
ARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPALRCAWLVVPVEQISQFRQQASL
EPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQWIEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAGL
AVQALSDWRIRSSEDGGLLLSFTNIVSESMARQVAQQLRSALN

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=311, Percent_Identity=25.7234726688103, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33469970, Length=311, Percent_Identity=25.7234726688103, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787710, Length=389, Percent_Identity=30.5912596401028, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790797, Length=415, Percent_Identity=29.6385542168675, Blast_Score=138, Evalue=8e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 49746; Mature: 49614

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHEECC
QAGTFVSEQIHPQQSAVDVVAFAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTR
CCCCCHHHHCCCCHHHHHHEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHGYAASMALILHALAQPGDGMW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
MEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALS
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHH
LARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPAL
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHH
RCAWLVVPVEQISQFRQQASLEPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQW
HHHHHEECHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAGLAVQALSDWRIRSSEDGGLL
HHHHHHHCCCEECCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCEE
LSFTNIVSESMARQVAQQLRSALN
EEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHEECC
QAGTFVSEQIHPQQSAVDVVAFAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTR
CCCCCHHHHCCCCHHHHHHEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHGYAASMALILHALAQPGDGMW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
MEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALS
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHH
LARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPAL
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHH
RCAWLVVPVEQISQFRQQASLEPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQW
HHHHHEECHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAGLAVQALSDWRIRSSEDGGLL
HHHHHHHCCCEECCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCEE
LSFTNIVSESMARQVAQQLRSALN
EEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]