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The map label for this gene is ade [H]

Identifier: 209400507

GI number: 209400507

Start: 4734200

End: 4735966

Strand: Direct

Name: ade [H]

Synonym: ECH74115_5095

Alternate gene names: 209400507

Gene position: 4734200-4735966 (Clockwise)

Preceding gene: 209398116

Following gene: 209396441

Centisome position: 84.96

GC content: 54.61

Gene sequence:

>1767_bases
ATGAATAATTCCATTAACCATAAATTTCATCACATTAGCCGGGCGGAATACCAGGAATTGTTAGCCGTTTCCCGTGGCGA
CGCTGTTGCCGATTATATTATTGATAATGTCTCTATTCTCGACCTGATTAATGGCGGAGAAATTTCCGGCCCAATTGTGA
TTAAAGGGCGTTACATTGCCGGTGTTGGCGCAGAATACACTGATGCTCCGGCTTTGCAGCGGATTGATGCCCACGGCGCA
ACGGCGGTGCCAGGGTTTATTGATGCTCACCTGCATATTGAATCCAGCATGATGACGCCGGTCACCTTTGAAACCGCCAC
CCTGCCTCGCGGCCTGACAACTGTTATTTGCGATCCTCATGAAATCGTCAACGTGATGGGCGAAGCCGGTTTCGCCTGGT
TTGCCCGCTGTGCCGAACAGGCAAGGCAAAACCAGTACTTACAGGTCAGCTCTTGCGTACCCGCTCTGGAAGGCTGCGAT
GTTAACGGTGCCAGTTTTACCCTTGAACAGATGCTCGCCTGGCGGGACCATCCGCAGGTTACCGGCCTTGCAGAAATGAT
GGACTACCCTGGCGTAATTAGCGGGCAGAATGCGCTGCTCGATAAACTGGATGCATTTCGCCACCTGACGCTGGACGGTC
ACTGCCCGGGTTTGGGTGGTAAAGAACTTAACGCCTATATTGCTGCGGGTATTGAAAACTGCCACGAAAGTTATCAGCTG
GAAGAAGGACGCCGGAAATTACAACTCGGCATGTCGTTGATGATCCGCGAAGGGTCCGCTGCCCGCAATCTCAACGCACT
GGCACCGTTGATCAACGAATTTAACAGCCCGCAATGCATGCTCTGTACTGATGACCGTAACCCGTGGGAGATCGCCCATG
AAGGACACATCGATGCCTTAATTCGCCGCCTGATCGAACAACACAATGTGCCGCTGCATGTGGCATATCGCGTCGCCAGC
TGGTCGACGGCGCGCCACTTTGGTCTGAATCACCTCGGCTTACTGGCACCTGGTAAGCAGGCTGATATCGTCCTGTTGAG
CGATGCGCGTAAGGTCACGGTGCAGCAGGTACTGGTGAAAGGCGAACCGATTGACGCGCAAACCTTACAGGCGGAAGAGT
CGGCGAAACTGGCACAATCCGCTCCGCCATATGGCAACACCATTGCCCGCCAGCCAGTTTCCGCCAGCGACTTTGCCCTG
CAATTTACGCCCGGAAAACGCTATCGGGTCATTGACGTCATCCATAACGAATTGATTACGCACTCCCACTCCAGCGTCTA
CAGCGAAAATGGTTTTGAGCGCAATGATGTGTGCTTTATTGCCGTACTTGAGCGTTACGGGCAACGTCTGGCTCCGGCTT
GTGGTTTGCTCGGCGGCTTTGGTCTGAATGAAGGCGCGCTGGCTGCGACGGTCAGCCATGACAGCCATAATATTGTGGTG
ATCGGTCGCAGTGCCGAAGAGATGGCGCTAGCGGTCAATCAGGTGATTCAGGATGGCGGCGGGTTGTGCGTGGTACGTAA
CGGCCAGGTCCAAAGCCATCTGCCGTTACCCATTGCCGGGCTGATGAGCACCGACACGGCGCAGTCGCTGGCGGAGCAAA
TTGACGCCTTGAAAGCCGCCGCCCGTGAATGCGGTCCGTTACCCGATGAGCCGTTTATTCAGATGGCGTTTCTTTCCCTG
CCAGTGATCCCCGCGCTGAAACTAACCAGCCAGGGGCTGTTTGATGGCGAGAAGTTTGCCTTCACCACGCTGGAAGTCAC
TGAATAA

Upstream 100 bases:

>100_bases
TCACATTTCAATTGCACATTAATGGATATTCTTTAATAATCTTGCGACATTTCTTTATGATAAATAACAATCAAATTAAT
AAAATCAAAATGAGAAAAAT

Downstream 100 bases:

>100_bases
TAAAAAAAGCCCGGCGTCATGCCGGGCAAAAGTCACCAGTTACGTTTATGCCACTGTCAACTGCTGAATTTTTTTCTCGC
GGCGGATTTTGCGTTCTTCC

Product: cryptic adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDAHGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Sequences:

>Translated_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDAHGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE
>Mature_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDAHGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=588, Percent_Identity=98.9795918367347, Blast_Score=1201, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 63692; Mature: 63692

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYTDAPALQRIDAHGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYTDAPALQRIDAHGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA