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The map label for this gene is lolC [H]

Identifier: 209400467

GI number: 209400467

Start: 1307106

End: 1308416

Strand: Direct

Name: lolC [H]

Synonym: ECH74115_1293

Alternate gene names: 209400467

Gene position: 1307106-1308416 (Clockwise)

Preceding gene: 209400877

Following gene: 209396483

Centisome position: 23.46

GC content: 47.6

Gene sequence:

>1311_bases
ATGTCCGGGGAAATTTTAGCTGTTAATTGCGTTCTGCTGCTGATTCTGTTTTTTGTGTTTTATCAGCTTCTGTTTTATTC
ACGAGATGTCAAATTTGCATTTTTGAATCTCTTTCGCCACAAGCGTCGCTCTTTTTCTACCATAACCGCTATTGTATTGG
GTGGCGTGGCAATTTTTTTATATGGCGGATTTATTGATTACTCTTTCTGGATCCTGAAAGAGCAGACGATTCGTACCAAT
ATTGGTCATGTACAAATTTACAATCAGCACTATTTTGAAACGTCGAATAAAAATAAGAGCCTGATTGCCGATTATGCGGC
GTTAAAGAAAGCTATTTTGTCGGACCCGACGCTGGCGGCGGATATTTCCACGCTCTCCGGGCAACTGGAGTTTACTGGCG
TAATTTCACATTACGAGAGCGAAACCTCCAGCTATTTCTCCGCGCTGGGGGGCGAGCCGTTACCCGCTTTAAAGCTGGGT
TCGTTCGATAAGATTATCGCGGGGAGCGATCTTTCCCGGGTAAAAGGTGATGAAATCACCCTGGGCAGCGGTCTGGCGAA
AACGTTGAATGCGAAATATGACGACTGGCTGGATGTGATGGTGGTCAACACGGCGGGCGGGCAGGGCGCATTGTCGCTAA
AAATGCGTGGCATTTTTGAGTCAGGCATTAAAGATTATGACGATGTCGCGATGAAGATCCCGCTGGACACCGCGCAGCGC
ATGATGGGTACGGATGGCGTCAGCAAAGTGCTTATTCTGCTTAAAGAGGATGACACCGCGGCGTTTAGCGCAAAGCTGCG
TCAATTTATCGAACGCAATCATTTGCCGCTGGTGGTCAAAGACTGGCGTGATGTTTCACTCTTTTATCAACAGGTTGAAG
GGTTGCTATCGGGGATCTATTTCTTCATCAAGCTGATTGTTGCGCTGATTGTCATCTTCATGATCGGCAACTCGATGGCA
ATGAACATTGTTGAGCGCACCCGTGAAATTACCACTCTGCGTGCCATAGGCCTGAAGCCGCTTCACGTCACGCGCTTGTT
TCTGACAGAAGGCATTTTTATTGGTGTGATTGGCGCAGTCGGCAGCCTGCTGGTGGGGGGCGTGTTAGCCTGGATTATTA
ATCTTTATGGTATTGCGATGCCGCCATCGCCGGGACAAACCATCGGCTATACCGCCTTTATAAAAACCAGTAACCCGGAA
TTGATTTGGGTGACGGTGGTATTACCTATTTTGACAGCAACAGGTGCCTCTGTGTTACCGGCTTTACGTGCTTCCCGGCT
GAATATTTCTGACGCATTTAAATTCTCATAG

Upstream 100 bases:

>100_bases
CGCGCTTGCGCAGTCGCTGACGCAGGATTTTAATGTTGTACCAGAATGGGATAGTGAAGAGTTAACCCAGGTACTGCTGC
CGCTGATGAAAGGTGAGTAA

Downstream 100 bases:

>100_bases
GGCTAATTATGAATATGGCTTTTTACGGCAAGTGGTTTGCTTGCCTGTGGCTCGCTACGTCGTGCGTTCAGGCGGCGAGC
ACAGATAATAAGGCGCTGGA

Product: efflux ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTN
IGHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSYFSALGGEPLPALKLG
SFDKIIAGSDLSRVKGDEITLGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQR
MMGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMA
MNIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPE
LIWVTVVLPILTATGASVLPALRASRLNISDAFKFS

Sequences:

>Translated_436_residues
MSGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTN
IGHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSYFSALGGEPLPALKLG
SFDKIIAGSDLSRVKGDEITLGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQR
MMGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMA
MNIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPE
LIWVTVVLPILTATGASVLPALRASRLNISDAFKFS
>Mature_435_residues
SGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTNI
GHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSYFSALGGEPLPALKLGS
FDKIIAGSDLSRVKGDEITLGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQRM
MGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMAM
NIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPEL
IWVTVVLPILTATGASVLPALRASRLNISDAFKFS

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48003; Mature: 47872

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFL
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGFIDYSFWILKEQTIRTNIGHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAA
HHHHHHHEEEEEECHHHHCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHH
DISTLSGQLEFTGVISHYESETSSYFSALGGEPLPALKLGSFDKIIAGSDLSRVKGDEIT
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHCCCCCEE
LGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQR
ECCCHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEHHHHHHCCCCCCCCEEECCHHHHHH
MMGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIY
HHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
FFIKLIVALIVIFMIGNSMAMNIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
GSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPELIWVTVVLPILTATGASVLP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCHHHHH
ALRASRLNISDAFKFS
HHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFL
CCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGFIDYSFWILKEQTIRTNIGHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAA
HHHHHHHEEEEEECHHHHCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHH
DISTLSGQLEFTGVISHYESETSSYFSALGGEPLPALKLGSFDKIIAGSDLSRVKGDEIT
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHCCCCCEE
LGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQR
ECCCHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEHHHHHHCCCCCCCCEEECCHHHHHH
MMGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIY
HHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
FFIKLIVALIVIFMIGNSMAMNIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
GSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPELIWVTVVLPILTATGASVLP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCHHHHH
ALRASRLNISDAFKFS
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]