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The map label for this gene is fitD [H]

Identifier: 209400446

GI number: 209400446

Start: 4017267

End: 4018304

Strand: Reverse

Name: fitD [H]

Synonym: ECH74115_4340

Alternate gene names: 209400446

Gene position: 4018304-4017267 (Counterclockwise)

Preceding gene: 209398999

Following gene: 209397497

Centisome position: 72.12

GC content: 50.39

Gene sequence:

>1038_bases
ATGAACGTCGGGCTACGTCCACTACGTGTTGGTAAGTTTTCGACACTGGTACGCCCTAAAAATCTGGTGTTGCTTGGTGG
GCTGTTTCTGTTTGCGGTTGGAATACTGATATTCGGTCTGATGCATGGTTCTTTTTTTGTCCCGGCATCGGAAGTAGGAC
GAGCGTTGTTTGCTCCAGAAAACGTAAGCACAGACGCACGTTATATTGTGCAGGATATTCGCTTGCCGAGAGTCATCATG
GCATTGCTATGCGGAGCCATGTTAGGTATGGCGGGGGCCGCGATGCAATCCATTGCGCGTAACGGCCTTGCCGATCCTGG
TTTAATCGGCGTCAAAGAAGGATGTAGCGTGGCGGTGCTGTGGCTGATTTTCCAGTTTCCAATGCTGGGAATGTTCTGGC
GTCCAGTGGCTGGTCTTGCTGGTGGCTTGTTGGTGGCTTTAATCGTGATTTTTTGTGCACGCGAAATTTCCCGCCCGCGA
TTTGTTCTGATTGGTATTGGTGTTTCCTGGTTTTTCGCCGCCGGTATCGGTGTATTTATGACCACTGCAGATGTTCGAGA
TGTACAAACTGCATTGATGTGGTTATCGGGAAGCCTGCATGCTGCTAACTGGATGTTAGTCGGTATTTCAGCCTGTTGGA
TGTTGCCAGCCGCTCTTTTATTGCTGTTCACCGCCAGGACGGCGGATATCGCTCTGCTTGGTCATCAGGTTGCAACCGGG
TTAGGGGTGAATAGTTCTCGTCTGGCGTTGTTACGTGTCGCCGCACCAATAATCCTGACAGCCGTCTGCGTTTCGTGTGT
TGGTAACATCGGTTTTGTCGGATTGATAGCACCCCATATATCACGTTTTATTCTACGTGGCGGGCAGACGACATTACTGC
TGGGGAGCGCCGTATCGGGGGCGTTGTTAGTCATCCTGGCGGATAGCATTGGTCGTTTGGCTTTTTTGCCTTTGCAACTG
CCTGCCGGAATCATTATTTCATTGATTGGTGGACCATTCTTTTTGCTACTGCTCTGGCAGCGCAGGAACAGTTTTTAA

Upstream 100 bases:

>100_bases
TTTTCACGCCCCATGAGTTAGCGACCGGTGTCATGACGGCGTTAGTTGGTGCGCCTGTTTTTGTCATTATGGCGACGAGA
ATGTTCAAATGAGTCGGATA

Downstream 100 bases:

>100_bases
TGGGAGTTATATGCGTTTATTTTTTTCTCTGCTGATACTGTTGTCATTCTTTGCCCGCGCGACAGAACCTGTTCAGGTCT
TTACTGATGATTTAGGGCGC

Product: iron ABC transporter, permease protein FitD

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPENVSTDARYIVQDIRLPRVIM
ALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPR
FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQL
PAGIIISLIGGPFFLLLLWQRRNSF

Sequences:

>Translated_345_residues
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPENVSTDARYIVQDIRLPRVIM
ALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPR
FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQL
PAGIIISLIGGPFFLLLLWQRRNSF
>Mature_345_residues
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPENVSTDARYIVQDIRLPRVIM
ALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPR
FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQL
PAGIIISLIGGPFFLLLLWQRRNSF

Specific function: Part of the ABC transporter complex feuABC/yusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=289, Percent_Identity=33.2179930795848, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790741, Length=332, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=318, Percent_Identity=33.0188679245283, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786347, Length=273, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788004, Length=295, Percent_Identity=31.1864406779661, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=31.5960912052117, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36573; Mature: 36573

Theoretical pI: Translated: 11.62; Mature: 11.62

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPE
CCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHCHHHCCCC
NVSTDARYIVQDIRLPRVIMALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVL
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHH
WLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPRFVLIGIGVSWFFAAGIGVFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHH
TTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHH
ALLVILADSIGRLAFLPLQLPAGIIISLIGGPFFLLLLWQRRNSF
HHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPE
CCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHCHHHCCCC
NVSTDARYIVQDIRLPRVIMALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVL
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHH
WLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPRFVLIGIGVSWFFAAGIGVFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHH
TTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHH
ALLVILADSIGRLAFLPLQLPAGIIISLIGGPFFLLLLWQRRNSF
HHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 8011666 [H]