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The map label for this gene is eprI [H]

Identifier: 209399756

GI number: 209399756

Start: 3824684

End: 3824923

Strand: Reverse

Name: eprI [H]

Synonym: ECH74115_4133

Alternate gene names: 209399756

Gene position: 3824923-3824684 (Counterclockwise)

Preceding gene: 209396063

Following gene: 209399138

Centisome position: 68.64

GC content: 39.17

Gene sequence:

>240_bases
ATGGCAGATTGGAATGGTTATATTATGGACATCAGCAAACAATTTGATCAGGGCGTTGATGATCTGAACCAGCAAGTTGA
AAAAGCGTTGGAGGATTTAGCAACCAATCCTTCCGACCCGAAATTCCTTGCCGAATATCAAAGTGCATTAGCTGAGTATA
CATTATATCGAAATGCGCAATCTAACGTTGTAAAAGCGTATAAAGATCTTGATTCGGCAATCATACAAAACTTCCGCTAA

Upstream 100 bases:

>100_bases
AATCAGGACACAAATAATAGTTCATTTAGCTACGGAGATAACCGATTCGAGAAGTCTCAAGGTAGCAAGTGGACATTTCA
GGAATAATTGAGGAGGACTT

Downstream 100 bases:

>100_bases
ACTGGATAAGGATTTTATTATGTCAGTAAGCAATATGCCACCTATTGATAGAGCTGAGCAATCAACTGCTCATGAAATAC
AGCAAGCGAAAGTGATTGAT

Product: type III secretion apparatus needle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR

Sequences:

>Translated_79_residues
MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR
>Mature_78_residues
ADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mxiH/prgI/yscF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021123
- InterPro:   IPR011841 [H]

Pfam domain/function: PF09392 MxiH [H]

EC number: NA

Molecular weight: Translated: 9038; Mature: 8907

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQ
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCH
SNVVKAYKDLDSAIIQNFR
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQ
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCH
SNVVKAYKDLDSAIIQNFR
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]