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The map label for this gene is csgA

Identifier: 209399619

GI number: 209399619

Start: 1407172

End: 1407630

Strand: Direct

Name: csgA

Synonym: ECH74115_1422

Alternate gene names: 209399619

Gene position: 1407172-1407630 (Clockwise)

Preceding gene: 209398648

Following gene: 209397004

Centisome position: 25.25

GC content: 50.33

Gene sequence:

>459_bases
ATGAAACTTTTAAAAGTAGCAGCAATTGCAGCAATCGTATTCTCCGGTAGCGCTCTGGCAGGTGTTGTTCCTCAGTACGG
CGGCGGTGGCGGTAACCACGGTGGTGGCGGTAATAACAGCGGCCCGAATTCAGAGCTGAATATTTATCAGTACGGTGGTG
GTAACTCTGCACTTGCTCTGCAAGCTGATGCTCGTAACTCTGATCTTACTATTACCCAGCATGGTGGTGGTAACGGTGCA
GATGTTGGTCAGGGCTCAGATGACAGCTCAATCGATCTGACCCAACGTGGCTTTGGTAACAGCGCCACTCTTGATCAGTG
GAACGGTAAAGACTCTCATATGACAGTTAAACAATTCGGTGGCGGCAACGGTGCAGCGGTTGACCAGACTGCATCTAATT
CCACCGTCAACGTAACTCAGGTTGGCTTTGGTAACAACGCGACCGCTCATCAGTACTAA

Upstream 100 bases:

>100_bases
AAAACGGCAATTGTAGTGCAGAGACAGTCGCAAATGGCTATTCGCGTGACACAACGTTAATTTCCATTCGACTTTTAAAT
CAATCCGATGGGGGTTTTAC

Downstream 100 bases:

>100_bases
TACATCATCTGTATTAAAGAAACAGGGCGCAAGCCCTGTTTTTTTTCGGGAGAAGAATATGAATGCGTTATTACTCCTTG
CGGCACTTTCCAGTCAGATA

Product: cryptic curlin major subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQADARNSDLTITQHGGGNGA
DVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFGGGNGAAVDQTASNSTVNVTQVGFGNNATAHQY

Sequences:

>Translated_152_residues
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQADARNSDLTITQHGGGNGA
DVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFGGGNGAAVDQTASNSTVNVTQVGFGNNATAHQY
>Mature_152_residues
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQADARNSDLTITQHGGGNGA
DVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFGGGNGAAVDQTASNSTVNVTQVGFGNNATAHQY

Specific function: Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium. Note=Part of the curli surface structure

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CsgA/CsgB family

Homologues:

Organism=Escherichia coli, GI1787279, Length=152, Percent_Identity=96.7105263157895, Blast_Score=248, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSGA_ECO57 (Q93U24)

Other databases:

- EMBL:   AF275733
- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D90806
- PIR:   H85665
- RefSeq:   NP_287176.1
- RefSeq:   NP_309447.1
- EnsemblBacteria:   EBESCT00000026298
- EnsemblBacteria:   EBESCT00000056175
- GeneID:   913991
- GeneID:   959371
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1676
- KEGG:   ecs:ECs1420
- GeneTree:   EBGT00050000011868
- HOGENOM:   HBG416349
- OMA:   SVTQVGF
- ProtClustDB:   PRK10051
- BioCyc:   ECOL83334:ECS1420-MONOMER
- GO:   GO:0009289
- InterPro:   IPR009742

Pfam domain/function: PF07012 Curlin_rpt

EC number: NA

Molecular weight: Translated: 15099; Mature: 15099

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALAL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEE
QADARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFG
EECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECC
GGNGAAVDQTASNSTVNVTQVGFGNNATAHQY
CCCCCEEECCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALAL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEE
QADARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFG
EECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECC
GGNGAAVDQTASNSTVNVTQVGFGNNATAHQY
CCCCCEEECCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11319125; 11206551; 11258796