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The map label for this gene is radC

Identifier: 209399382

GI number: 209399382

Start: 4658854

End: 4659522

Strand: Reverse

Name: radC

Synonym: ECH74115_5008

Alternate gene names: 209399382

Gene position: 4659522-4658854 (Counterclockwise)

Preceding gene: 209396513

Following gene: 209397282

Centisome position: 83.62

GC content: 47.68

Gene sequence:

>669_bases
GTGAAAAACAATGCACAGCTGTTGATGCCGCGCGAAAAAATGCTGAAGTTTGGTATTAGCGCCTTAACTGATGTCGAGCT
GCTGGCGCTATTTCTGCGTACCGGAACGCGCGGTAAAGATGTATTAACCCTGGCAAAAGAGATGCTGGAGAATTTCGGCT
CTCTTTATGGCTTGTTAACCTCTGAATATGAACAATTTAGTGGTGTTCATGGAATTGGCGTAGCGAAATTTGCCCAGTTA
AAGGGGATTGCTGAACTGGCGCGACGTTACTACAACGTGCGGATGCGTGAAGAAAGCCCTTTACTCAGCCCGGAGATGAC
GCGGGAATTTTTACAAAGCCAGCTCACGGGTGAGGAGCGGGAGATCTTTATGGTGATCTTTCTCGACTCCCAACACCGGG
TTATAACGCATAGCCGTCTTTTTTCCGGCACGCTAAACCATGTTGAAGTCCATCCTCGGGAAATTATCCGCGAAGCGATA
AAAATAAACGCCTCGGCGCTGATCCTTGCACATAATCACCCTTCGGGTTGTGCTGAACCCAGTAAAGCGGATAAACTCAT
TACTGAACGGATAATAAAGAGTTGTCAGTTCATGGATTTACGCGTGCTCGACCATATCGTGATTGGGCGTGGAGAGTATG
TTTCTTTTGCCGAACGCGGCTGGATTTAA

Upstream 100 bases:

>100_bases
CCTGAGATTCACTTTGCGAGGCGCTTTCCAGGATTGAAAACTGGCCGTCGATTTAACGGAACGGCTATGACAGGATGCGA
GCACCACAAAGGAGGTGAAG

Downstream 100 bases:

>100_bases
CCCGCTATGCGCGATCCTTCGGGATCTTTGTCTGTTCGGGACTTGAGCACATCGCTGAGTCAGCGTATACTACGCCACCT
TTGAGAATCTCGGGTTTGGC

Product: DNA repair protein RadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQL
KGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI

Sequences:

>Translated_222_residues
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQL
KGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
>Mature_222_residues
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQL
KGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI

Specific function: Involved In DNA Repair. [C]

COG id: COG2003

COG function: function code L; DNA repair proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0758 family. YicR subfamily

Homologues:

Organism=Escherichia coli, GI87082300, Length=222, Percent_Identity=99.0990990990991, Blast_Score=452, Evalue=1e-129,
Organism=Escherichia coli, GI1788997, Length=120, Percent_Identity=45.8333333333333, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI2367100, Length=120, Percent_Identity=47.5, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1788312, Length=118, Percent_Identity=49.1525423728814, Blast_Score=127, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YICR_ECO24 (A7ZTI9)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001465118.1
- ProteinModelPortal:   A7ZTI9
- SMR:   A7ZTI9
- STRING:   A7ZTI9
- EnsemblBacteria:   EBESCT00000022755
- GeneID:   5590288
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_4139
- eggNOG:   COG2003
- GeneTree:   EBGT00050000009782
- HOGENOM:   HBG751042
- OMA:   HAAMAHE
- ProtClustDB:   PRK00024
- BioCyc:   ECOL331111:ECE24377A_4139-MONOMER
- HAMAP:   MF_00018
- InterPro:   IPR010994
- InterPro:   IPR001405
- InterPro:   IPR020891
- InterPro:   IPR022820
- TIGRFAMs:   TIGR00608

Pfam domain/function: PF04002 DUF2466; SSF47781 RuvA_2_like

EC number: NA

Molecular weight: Translated: 25259; Mature: 25259

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS01302 UPF0758

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLT
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEER
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
EIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEP
EEEEEEEECCCCCCHHHHHHHHCCCCCEEECHHHHHHHHHHCCCEEEEEEECCCCCCCCC
SKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLT
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEER
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
EIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEP
EEEEEEEECCCCCCHHHHHHHHCCCCCEEECHHHHHHHHHHCCCEEEEEEECCCCCCCCC
SKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA