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The map label for this gene is rfaL [H]

Identifier: 209399220

GI number: 209399220

Start: 4646905

End: 4648113

Strand: Direct

Name: rfaL [H]

Synonym: ECH74115_4995

Alternate gene names: 209399220

Gene position: 4646905-4648113 (Clockwise)

Preceding gene: 209399933

Following gene: 209400697

Centisome position: 83.4

GC content: 35.24

Gene sequence:

>1209_bases
ATGACCTCAACATTATTTTTCTCTCTCGAGAAAAAAAACTGGATAGCGTACTGGAACAGAGCTCTCGTATTCTTATTCAT
TACCACCTATTTTTTGGGTGGGATTACAAGGTATAAACATCTTATTGTTATTCTTATGACAATAACGACAATCGTCTATC
TCTGCAAACGGCCAAAACACTATCTCTCACTATTTAAAACATTTCTTTTTGGTAGTGTTGCCATATTAACTATTGCTGCA
TTGCTGTCACTTCTTCAATCCCCTGATGCAGGTGCTAGCATGAAGGAAATTTTCAAAGCTATTATTGAGAATACTTTACT
ATGCACAATAGCAATACCGATCATATTGAGAGACGAGAAAAGAGAAGATGTCGAAAAAATCGTTTTCTTCTCATTTATTA
GTGCGTTGGGCTTACGCTGTTTTTCTGAATTGATTACCTATTATAAGGACTATCAACAAGGGATAATGCCATTCGCAGAT
TATAGACACCGTAGCATTTCTGACTCGATGGTCTTTTTATTCCCTGCATTGTTAAATCTCTGGCTTATCAAATCAGCAAA
ATACCGCATTTCTTTTGTGGTTCTAAGCGTTATTTTTATTTTTCTGATATTAGGAACTTTATCCAGAGGGGCCTGGCTTT
CCGTGTTAGTCATTGGATTAATATGGATTCTGATGTTTAAACAATGGAAGTTACTATTAGTAGGAGTAATGGTTGCCATC
ATTGCATTGTCGGTTATTTTCACACATAAGGAGATGACCGCAAAGCTAACGTATAAACTTCAACAAACTAATAGTTCTTA
TCGCTATGCAAATGGTACTCAAGGCAGCGCACTCGATCTAATATTAGAAAATCCTGTTATTGGTTATGGTTACGGTAACG
TTGCATATAAAGATGTCTATAATAAACGTGTCATTGATTATCCAGAATGGACCTTTAGACAATCAATAGGGCCACATAAT
TTTGCGCTATTCATCTGGTTTGGCACTGGTTTATTAGGGCTGGTAAGTCTTATGATGCTATACTGTGCAATATTGAAAGA
GTGTATAAAAAATGGCGTCAAGAATAAATATCGCTCACCATATAATGCATATTATATAATCTTACTATCTTTTATAGGTT
ATTTTGTTATCCGTGGAAACGTAGAACAAATTGAACCAAATTTATTAGGCGTTTACGCCGGCTTATTATTAGCGATGAAA
AACAAGTAA

Upstream 100 bases:

>100_bases
GTCGTTCTACAAGTATGTCTCTTGCAGATTTGCCAGCTCAAACCGTTTTTCAAAATTTAAATCTTGAAATAATAACCAAT
AAGTTGACATCGGAGATAAG

Downstream 100 bases:

>100_bases
AAAATAAAAAAGGCTGCATAATGCGGCCTTTTTATTTATTCAAACCAATTATGAATAACCTCTTCGAATCTTTGAGTTAC
GCCATCCCAACTGTAGTGAT

Product: lipid A-core:surface polymer ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKHYLSLFKTFLFGSVAILTIAA
LLSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEKREDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFAD
YRHRSISDSMVFLFPALLNLWLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAI
IALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVYNKRVIDYPEWTFRQSIGPHN
FALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSPYNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMK
NK

Sequences:

>Translated_402_residues
MTSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKHYLSLFKTFLFGSVAILTIAA
LLSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEKREDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFAD
YRHRSISDSMVFLFPALLNLWLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAI
IALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVYNKRVIDYPEWTFRQSIGPHN
FALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSPYNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMK
NK
>Mature_401_residues
TSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKHYLSLFKTFLFGSVAILTIAAL
LSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEKREDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFADY
RHRSISDSMVFLFPALLNLWLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAII
ALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVYNKRVIDYPEWTFRQSIGPHNF
ALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSPYNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMKN
K

Specific function: Adds the O-antigen on the glucose(II) group of LPS [H]

COG id: COG3307

COG function: function code M; Lipid A core - O-antigen ligase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the O-antigen polymerase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007016 [H]

Pfam domain/function: PF04932 Wzy_C [H]

EC number: 6.-.-.-

Molecular weight: Translated: 46100; Mature: 45969

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKH
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YLSLFKTFLFGSVAILTIAALLSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCC
REDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFADYRHRSISDSMVFLFPALLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHH
WLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAI
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVY
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHH
NKRVIDYPEWTFRQSIGPHNFALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSP
CCCCCCCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMKNK
CHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKH
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YLSLFKTFLFGSVAILTIAALLSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCC
REDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFADYRHRSISDSMVFLFPALLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHH
WLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAI
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVY
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHH
NKRVIDYPEWTFRQSIGPHNFALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSP
CCCCCCCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMKNK
CHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1657881; 11677609 [H]