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The map label for this gene is ygeK

Identifier: 209398226

GI number: 209398226

Start: 3821499

End: 3822131

Strand: Reverse

Name: ygeK

Synonym: ECH74115_4126

Alternate gene names: 209398226

Gene position: 3822131-3821499 (Counterclockwise)

Preceding gene: 209397604

Following gene: 209396603

Centisome position: 68.59

GC content: 36.49

Gene sequence:

>633_bases
ATGGGAAAAATTAAAATTGTAGTTTCAGATCAGCAGCCGTTTATGATTGATGGGATAATTGGATTCCTCGGACATTATCC
CGATTTATATGAGGTTGTTGGGGGCTATAAAGATCTGAAGAAAGCTATAGCGGAGTGTAACAAATCTGCAGCCCAAATAT
TTATTTTAGGAGAATTTGCAGGTGGAATGATGGGGGCCGAACTCGTAAAATGGGTTAAATCGCATAAAATAGATGCTCAT
ATTATTACATTTGTAGCAAAAATGCCGTATATTGATTCAATAAAATTGCTTGAAGCAGGTGCGAAAGGATGCGTATGGAA
AACCAGTCACCCGGCGAAACTTAATCGCGCTATTGATTCGATTAGTAACGGCTACACTTATTTTGATAGTGTACATATGG
ATTGTGAGAAAATATCTTCCAGATATTCCTCTGATAATCAACTTACAAATCGTGAGTCTGAAATATTACAACTCATAGCT
GATGGAAAAACAAACAAAGAAATCGCTAATTTCTTGCAGTTAAGCAGGAAAACAGTCGAAACTCATAGACTCAATATCAT
GAAGAAATTAGATGTTCACAGTGGTATCGAGTTGATCAAAACAGCTTTACGTATGGGTGTGTGCACTATATAA

Upstream 100 bases:

>100_bases
TATTATTTCATCAATGTATTCTTTGGATTTTGCTTATAATAATAATGAAAGGGATGATTATAAATGAATGCGTTAAAGCA
TTTACACTCAGGATGAATAT

Downstream 100 bases:

>100_bases
AAAAAAGAGGCTTTAGGCTCATTTTGCTAAAGCCTTACGATTGTCTAGTTCATTAAGCCTGGTATATACAATATATATTT
TTTTGGCATATTGCAGTCGC

Product: transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFAGGMMGAELVKWVKSHKIDAH
IITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIA
DGKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI

Sequences:

>Translated_210_residues
MGKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFAGGMMGAELVKWVKSHKIDAH
IITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIA
DGKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI
>Mature_209_residues
GKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFAGGMMGAELVKWVKSHKIDAHI
ITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIAD
GKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788222, Length=186, Percent_Identity=28.494623655914, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=30.6532663316583, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=30.0970873786408, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=25.6281407035176, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YGEK_ECO57 (P58664)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D85938
- PIR:   H91092
- RefSeq:   NP_289409.1
- RefSeq:   NP_311739.1
- ProteinModelPortal:   P58664
- SMR:   P58664
- EnsemblBacteria:   EBESCT00000029034
- EnsemblBacteria:   EBESCT00000059423
- GeneID:   916468
- GeneID:   958324
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4176
- KEGG:   ecs:ECs3712
- GeneTree:   EBGT00050000008652
- HOGENOM:   HBG753323
- OMA:   SREREIV
- ProtClustDB:   CLSK880510
- BioCyc:   ECOL83334:ECS3712-MONOMER
- GO:   GO:0005622
- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 23397; Mature: 23265

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFA
CCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECHH
GGMMGAELVKWVKSHKIDAHIITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDS
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHH
ISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIADGKTNKEIANFLQLSRKTVE
HHCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
THRLNIMKKLDVHSGIELIKTALRMGVCTI
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFA
CEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECHH
GGMMGAELVKWVKSHKIDAHIITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDS
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHH
ISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIADGKTNKEIANFLQLSRKTVE
HHCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
THRLNIMKKLDVHSGIELIKTALRMGVCTI
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796