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The map label for this gene is appB [H]

Identifier: 209398204

GI number: 209398204

Start: 1223449

End: 1224585

Strand: Direct

Name: appB [H]

Synonym: ECH74115_1215

Alternate gene names: 209398204

Gene position: 1223449-1224585 (Clockwise)

Preceding gene: 209399125

Following gene: 209397629

Centisome position: 21.96

GC content: 53.21

Gene sequence:

>1137_bases
ATGTTTGATTATGAAACATTGCGCTTCATCTGGTGGCTGCTGATTGGCGTGATCCTGGTGGTCTTTATGATCTCCGACGG
ATTTGACATGGGGATTGGCTGTTTGCTGCCGCTGGTGGCGCGTGATGATGATGAACGCCGGATAGTGATTAATAGCGTTG
GTGCGCACTGGGAAGGCAATCAGGTCTGGTTGATCCTCGCAGGTGGGGCATTATTTGCCGCCTGGCCCAGAGTGTATGCA
GCGGCGTTTTCCGGCTTTTATGTGGCGATGATCCTGGTGCTGTGCTCGCTGTTCTTCCGCCCGCTGGCCTTTGATTATCG
CGGAAAAATCGCCGATGCACGCTGGCGTAAAATGTGGGATGCCGGTCTGGTCATCGGCAGTCTGGTGCCGCCGGTAGTCT
TCGGTATCGCCTTCGGCAACTTGTTGCTCGGCGTGCCGTTTGCCTTCACTCCGCAATTACGCGTGGAGTATCTCGGCAGC
TTCTGGCAACTGCTGACGCCATTCCCTTTATTGTGCGGATTGCTCAGCCTTGGGATGGTGATTTTGCAAGGTGGCGTCTG
GTTACAACTGAAAACTGTTGGTGTGATTCATCTGCGTTCACAGCTGTCGACTAAACGCGCTGCACTGTTGGTGATGCTGT
GCTTTTTGCTGGCGGGTTACTGGCTGTGGGTCGGTATTGATGGCTTTGTACTGCTCGCCCAGGATGCTAACGGTCCTTCC
AATCCGTTAATGAAACTGGTGGCAGTGCTACCTGGTGCCTGGATGAATAATTTTGTCGAGTCGCCCGTTTTGTGGATCTT
CCCGCTGCTGGGGTTCTTCTGCCCATTGCTGACGGTGATGGCGATTTATCGTGGCCGCCCGGGTTGGGGATTTTTGATGG
CGTCATTGATGCAATTTGGCGTGATTTTCACGGCAGGCATCACGCTGTTCCCCTTTGTCATGCCGTCAAGCGTGAGTCCA
ATCTCCAGCCTGACGTTGTGGGACAGCACTTCCAGTCAGCTGACGCTGAGTATTATGTTGGTAATCGTGCTGATATTTTT
GCCCATTGTGTTGCTCTACACTCTCTGGAGCTACTACAAAATGTGGGGGCGCATGACGACAGAAACTCTCCGCCGTAACG
AAAACGAGCTGTACTAA

Upstream 100 bases:

>100_bases
TAATCGCCGAAGTCTACCTGATGCAGAAATATGCCCGTCTGGGGCCGAGCGCGATGCAGAGTGAACAACCGACGCAGCAA
CAGGGGTAAAGGAGAAAATC

Downstream 100 bases:

>100_bases
GGAGCAGGAACAATGTGGTATTTACTTTGGTTCGTCGGCATTTTGTTGATGTGTTCGCTCTCCACCCTTGTGTTGGTATG
GCTGGACCCGCGATTGAAAA

Product: cytochrome bd-II oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit II [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY

Sequences:

>Translated_378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY
>Mature_378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1294

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli CydB [H]

Homologues:

Organism=Escherichia coli, GI1787213, Length=378, Percent_Identity=99.4708994708995, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI1786954, Length=379, Percent_Identity=57.2559366754617, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003317 [H]

Pfam domain/function: PF02322 Cyto_ox_2 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 42441; Mature: 42441

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCC
QVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWD
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGSFWQLLTPFPLLCGLLSLGMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFG
HHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYK
HHHHHHHHHHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWGRMTTETLRRNENELY
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCC
QVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWD
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGSFWQLLTPFPLLCGLLSLGMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFG
HHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYK
HHHHHHHHHHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWGRMTTETLRRNENELY
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]