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The map label for this gene is yjjN [H]

Identifier: 209397114

GI number: 209397114

Start: 5527973

End: 5528995

Strand: Direct

Name: yjjN [H]

Synonym: ECH74115_5871

Alternate gene names: 209397114

Gene position: 5527973-5528995 (Clockwise)

Preceding gene: 209396680

Following gene: 209399682

Centisome position: 99.21

GC content: 51.81

Gene sequence:

>1023_bases
ATGTCTACGATGAATGTTTTAATTTGCCAGCAGCCGAAAGAATTAGTCTGGAAACAACGCGAGATACCTATTCCGGGTGA
CAATGAAGCATTAATAAAAATTAAGTCTGTCGGGATTTGCGGTACCGATATTCATGCCTGGGGTGGAAATCAACCATTTT
TTAGTTATCCACGGGTTTTAGGCCATGAAATATGTGGGGAGATTGTTGGGCTGGGTAAAAATATTGCTGATCTTAAAAAT
GGTCAGCAAGTTGCTGTGATCCCTTATGTTGCCTGTCAGCAATGCCCGGCGTGTAAAAGCGGGCGTACCAATTGCTGTGA
AAAAATTTCAGTCATTGGCGTGCATCAGGATGGCGGTTTTAGTGAGTATTTGAGCGTGCCGGTGGCGAACATTTTGCCCG
CAGACGGTATTGACCCGCAGGCGGCCGCATTGATTGAACCTTTCGCTATTAGCGCTCATGCGGTGCGTCGCGCAGCCATT
GCTCCCGGCGAGCAGGTGCTGGTGGTCGGGGCCGGGCCAATCGGTCTGGGCGCGGCGGCAATCGCTAAAGCCGATGGCGC
ACAGGTGGTGGTGGCGGATACCAGTCCGGCGCGCCGTGAACATGTGGCAACGCGTCTGGAGTTGCCCGTGCTGGACCCGT
CAGCCGAAGATTTTGACGCGCAGCTGCGGGCGCAGTTTGGTGGTTCGCTGGCGCAGAAAGTGATCGACGCGACAGGTAAT
CAACATGCGATGAATAACACCGTGAATCTGATTCGTCACGGCGGCACGGTGGTATTTGTCGGCCTGTTTAAAGGTGAGTT
GCAGTTCTCCGATCCGGAATTCCATAAAAAAGAAACGACGATGATGGGCAGCCGCAACGCCACGCCGGAAGATTTTGCTA
AAGTCGGTCGACTGATGGCGGAAGGAAAAATCACTGCTGGCATGATGTTAACCCATCGCTATCCGTTCGCCACGCTGGCA
GAAACCTACGAGCGCGATGTGATTAACAATCGTGAGTTAATTAAAGGCGTAATTACTTTCTGA

Upstream 100 bases:

>100_bases
ACATTTTTATGCGTGTGTTTTCACAAAACAGATTTTCCGTTCCGCTGCCATTTTTCATTTTCATTGATATCTAAGGCAAC
AAAAAATGGAGAGCCGAATC

Downstream 100 bases:

>100_bases
AAGGCGAGATTATTAAAGTTGCCATGCAGCGTCCGGGGAAGTGTTGGGCGCTGTTTTTTTTGTTTCTTAATAATGTGTTG
TAAGCCGGAGAAGGTGTGTA

Product: oxidoreductase, zinc-binding dehydrogenase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKN
GQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITAGMMLTHRYPFATLA
ETYERDVINNRELIKGVITF

Sequences:

>Translated_340_residues
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKN
GQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITAGMMLTHRYPFATLA
ETYERDVINNRELIKGVITF
>Mature_339_residues
STMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNG
QQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIA
PGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGNQ
HAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITAGMMLTHRYPFATLAE
TYERDVINNRELIKGVITF

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=335, Percent_Identity=31.9402985074627, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI71743840, Length=364, Percent_Identity=22.8021978021978, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI262073058, Length=373, Percent_Identity=23.8605898123324, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI71565154, Length=203, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4501929, Length=372, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI34577061, Length=360, Percent_Identity=25, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4501939, Length=221, Percent_Identity=24.4343891402715, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI156523966, Length=221, Percent_Identity=24.4343891402715, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI226510992, Length=340, Percent_Identity=99.4117647058823, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI1787863, Length=341, Percent_Identity=31.3782991202346, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1788073, Length=343, Percent_Identity=29.4460641399417, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790045, Length=330, Percent_Identity=29.6969696969697, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788407, Length=318, Percent_Identity=29.874213836478, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=27.9538904899135, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790718, Length=306, Percent_Identity=29.7385620915033, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082125, Length=324, Percent_Identity=27.7777777777778, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786825, Length=385, Percent_Identity=26.7532467532467, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081918, Length=312, Percent_Identity=28.525641025641, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786518, Length=257, Percent_Identity=28.7937743190661, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082401, Length=285, Percent_Identity=25.6140350877193, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786552, Length=241, Percent_Identity=27.3858921161826, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=325, Percent_Identity=30.1538461538462, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562878, Length=336, Percent_Identity=29.1666666666667, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988145, Length=253, Percent_Identity=30.8300395256917, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=274, Percent_Identity=29.9270072992701, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=324, Percent_Identity=28.0864197530864, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=352, Percent_Identity=24.7159090909091, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=354, Percent_Identity=24.5762711864407, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565904, Length=259, Percent_Identity=27.4131274131274, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=346, Percent_Identity=28.0346820809249, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6319955, Length=346, Percent_Identity=27.7456647398844, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323099, Length=354, Percent_Identity=29.0960451977401, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319257, Length=358, Percent_Identity=29.3296089385475, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323961, Length=341, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=324, Percent_Identity=26.8518518518519, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324486, Length=333, Percent_Identity=30.03003003003, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=268, Percent_Identity=31.7164179104478, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323729, Length=345, Percent_Identity=27.2463768115942, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=361, Percent_Identity=23.8227146814404, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323980, Length=185, Percent_Identity=33.5135135135135, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319949, Length=262, Percent_Identity=27.8625954198473, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737897, Length=323, Percent_Identity=33.1269349845201, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17137530, Length=323, Percent_Identity=31.8885448916409, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17737895, Length=379, Percent_Identity=25.065963060686, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45550770, Length=320, Percent_Identity=26.875, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45551930, Length=320, Percent_Identity=26.875, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221457811, Length=320, Percent_Identity=26.875, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36376; Mature: 36245

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVL
CCCCEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCEECCCEECCCCCCCCHHHHHHH
GHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
HHCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
EGKITAGMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCCEECEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
STMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVL
CCCEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCEECCCEECCCCCCCCHHHHHHH
GHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
HHCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
EGKITAGMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCCEECEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]