Click here to switch to the map view.

The map label for this gene is fiu

Identifier: 209397104

GI number: 209397104

Start: 967063

End: 969345

Strand: Reverse

Name: fiu

Synonym: ECH74115_0954

Alternate gene names: 209397104

Gene position: 969345-967063 (Counterclockwise)

Preceding gene: 209397684

Following gene: 209398451

Centisome position: 17.4

GC content: 53.75

Gene sequence:

>2283_bases
ATGGAAAACAATCGCAATTTCCCTGCCAGACAATTTCATTCGCTCACGTTCTTTGCCGGTCTTTGTATTGGCATCACGCC
TGTGGCTCAGGCACTCGCCGCCGAAGGGCAAACTAACGCGGATGACACGCTGGTTGTCGAAGCATCAACGCCTTCGCTTT
ATGCGCCACAACAATCTGCCGATCCGAAATTCTCGCGTCCGGTAGCGGATACTACCCGCACGATGACGGTGATTTCTGAA
CAAGTGATTAAAGATCAGGGCGCAACCAACCTTACCGATGCGCTCAAAAACGTCCCCGGCGTGGGTGCGTTTTTTGCGGG
TGAGAACGGTAACTCCACCACTGGCGACGCCATTTATATGCGCGGTGCTGATACCTCTAACAGTATTTATATTGATGGCA
TTCGCGATATCGGCAGCGTCTCGCGCGACACCTTCAATACTGAGCAGGTCGAAGTGATTAAAGGGCCTTCCGGCACCGAC
TACGGGCGCAGCGCGCCGACGGGCTCGATCAATATGATCAGCAAGCAGCCGCGCAATGATTCCGGCATTGACGCCTCCGC
CAGTATTGGCAGCGCCTGGTTCCGCCGCGGCACGCTGGACGTCAATCAGGTCATTGGTGATACCACTGCGGTGCGCCTGA
ATGTGATGGGCGAAAAAACGCACGATGCCGGACGCGACAAAGTCAAAAATGAGCGTTACGGCGTCGCCCCTTCTATCGCT
TTTGGCCTTGGTACAGCGAATCGTTTGTATCTTAATTATCTGCATGTCACCCAGCACAACACGCCAGACGGCGGCATTCC
AACCATCGGTTTGCCGGGCTATTCTGCCCCATCTGCAGGAACGGCGACCCTGAATCATTCCGGAAAAGTTGATACGCATA
ACTTTTACGGCACGGATTCCGATTACGACGATTCGACCACCGACACCGCCACCATGCGTTTTGAGCACGATATCAACGAT
AACACCACCATTCGCAACACTACCCGTTGGTCGCGCGTGAAGCAGGATTACCTGATGACGGCGATTATGGGTGGGGCGTC
GAATATTACCCAGCCCACCAGCGATGTGAATAGCTGGACGTGGTCACGCACGGCGAATACCAAAGATGTGAGTAATAAAA
TTCTCACCAACCAGACCAACCTGACCTCGACGTTCTATACCGCTTCTATCGGTCATGATGTCAGTACCGGCGTGGAATTT
ACCCGTGAAACGCAGACTAACTACGGCGTTAATCCGGTGACGTTACCTGCGGTAAATATTTATCATCCTGACAGCAGCAT
TCATCCCGGCGGCCTGACGCGCAACGGCGCAAACGCCAATGGTCAGACGGATACCTTCGCAATTTACGCATTCGATACGC
TGCAAATCACCCGTGATTTTGAGCTGAACGGCGGGATCCGTCTGGATAATTATCATACTGAATATGACAGTGCCACCGCC
TGCGGCGGCAGCGGACGCGGTGCCATCACCTGCCCAGCTGGTGTGGCAAAAGGTTCTCCGGTCACCACCGTCGACACCGC
CAAGTCGGGCAATCTGGTGAACTGGAAAGCCGGGGCGCTGTATCACCTGACGGAAAACGGCAATGTCTATATTAACTATG
CCGTTTCCCAGCAGCCTCCGGGCGGCAACAACTTCGCCCTTGCGCAGTCTGGCAGCGGTAACAGTGCCAACCGCACCGAT
TTTAAACCGCAAAAAGCCAACACCAGCGAGATTGGCACCAAATGGCAGGTTCTGGATAAACGCCTGTTGCTCACCGCCGC
GCTGTTCCGTACTGATATCGAAAATGAAGTTGAGCAAAATGATGACGGGACTTACTCGCAATACGGTAAGAAACGCGTCG
AAGGCTATGAGATATCCGTGGCAGGGAATATCACTCCCGCGTGGCAGGTGATTGGCGGCTATACCCAGCAAAAAGCAACC
ATCAAAAACGGCAAAGATGTTGCCCAGGATGGTTCCTCATCGCTGCCGTATACCCCGGAGCACGCCTTCACCTTATGGAG
CCAATATCAGGCAACCGATGATATCTCTGTTGGCGCGGGCGCACGCTATATCGGCAGTATGCATAAAGGTTCAGACGGCG
CGGTGGGAACGCCAGCGTTTACCGAAGGTTACTGGGTCGCCGATGCCAAACTGGGGTATAGGGTTAATCGCAATCTCGAC
TTCCAGCTAAACGTCTACAACCTGTTTGATACCGATTACGTCGCCTCAATCAATAAGAGCGGCTACCGTTATCACCCGGG
CGAGCCAAGAACCTTCTTGCTCACAGCCAATATGCATTTCTGA

Upstream 100 bases:

>100_bases
GCACGAACACTATCACGAGATTAACAGTGGCATCGCATCCGCAGAGAGGCTTTCTCGTGGCAGTGAAAATTTCAACATAT
AAGAAAAAGTCACCTGCAAA

Downstream 100 bases:

>100_bases
TTCAGATGTGGGGCGCAGGCCCCACTTTTTGGAGAACTTGTATGATGTACCACATTCCCGGCGTGTTATCGCCACAGGAC
GTCGCCCGTTTTCGCGAACA

Product: catecholate siderophore receptor Fiu

Products: NA

Alternate protein names: Ferric iron uptake protein; TonB-dependent receptor fiu

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Sequences:

>Translated_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
>Mature_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Specific function: Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein

COG id: COG4774

COG function: function code P; Outer membrane receptor for monomeric catechols

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family

Homologues:

Organism=Escherichia coli, GI1787024, Length=760, Percent_Identity=99.3421052631579, Blast_Score=1556, Evalue=0.0,
Organism=Escherichia coli, GI1786344, Length=818, Percent_Identity=24.5721271393643, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1790405, Length=207, Percent_Identity=29.951690821256, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787723, Length=256, Percent_Identity=28.515625, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIU_ECO57 (Q8X7W7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C90739
- PIR:   E85589
- RefSeq:   NP_286569.1
- RefSeq:   NP_308910.1
- HSSP:   P06129
- ProteinModelPortal:   Q8X7W7
- EnsemblBacteria:   EBESCT00000027269
- EnsemblBacteria:   EBESCT00000060235
- GeneID:   917629
- GeneID:   958041
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1026
- KEGG:   ecs:ECs0883
- GeneTree:   EBGT00070000031718
- HOGENOM:   HBG542811
- OMA:   AWQMIGG
- ProtClustDB:   PRK09840
- BioCyc:   ECOL83334:ECS0883-MONOMER
- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105
- Gene3D:   G3DSA:2.170.130.10
- Gene3D:   G3DSA:2.40.170.20
- TIGRFAMs:   TIGR01783

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec

EC number: NA

Molecular weight: Translated: 81957; Mature: 81957

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00430 TONB_DEPENDENT_REC_1; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796