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The map label for this gene is intD [H]

Identifier: 209397064

GI number: 209397064

Start: 302633

End: 303607

Strand: Reverse

Name: intD [H]

Synonym: ECH74115_0290

Alternate gene names: 209397064

Gene position: 303607-302633 (Counterclockwise)

Preceding gene: 209397548

Following gene: 209399294

Centisome position: 5.45

GC content: 47.38

Gene sequence:

>975_bases
ATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGATCGGATTCTGGCTTCAACATTT
CGCAGGAATGCAACTAAGAGACATTACTGAATCAAAAATTTATTCAGCAATGCAGAAAATGACGAACCGGCGTCATGAGG
AAAACTGGAAACTCAGGGCAGAAGCATGCAGAAAAAAAGGGAAACCTGTTCCAGAATACACGCCAAAACCAGCGTCCGTT
GCAACGAAGGCTACGCATCTTTCATTTATAAAGGCCCTGCTAAGAGCCGCAGAGCGTGAATGGAAAATGCTCGATAAGGC
ACCAATTATTAAAGTGCCTCAACCAAAGAATAAACGGATCCGCTGGCTGGAGCCCCATGAAGCACAAAGGCTGATTGATG
AATGTCCGGAGCCATTAAAGTCTGTTGTTGAATTTGCACTGGCAACAGGCTTAAGACGCTCGAACATCATCAACCTTGAA
TGGCAACAAATAGATATGCAGCGCCGGGTGGCATGGATAAACCCGGAAGAGAGTAAATCAAACCGCGCAATTGGCGTTGC
GCTGAATGATACTGCATGTCGCGTATTGAAAAAACAAATCGGTAATCATCACCGTTGGGTATTTGTGTACAAGGAAAGCT
GTACCAAACCAGACGGAACGAAAGCGCCAACAGTAAGGAAGATGCGGTATGACGCAAACACAGCCTGGAAAGCGGCGCTG
AGACGGGCTGGTATTGATGATTTCAGATTTCACGACTTGAGACACACCTGGGCAAGTTGGCTGGTTCAAGCCGGAGTCCC
GTTGTCAGTGTTACAGGAAATGGGAGGCTGGGAGTCTATCGAAATGGTTCGTCGATATGCTCACCTTGCACCTAATCACC
TTACCGAACACGCACGGCAAATAGACTCGATCCTGAACCCATCGGTCCCAAATTTGTCCCAGTCAAAAAATAAGGAAGGT
ACTAATGATGTGTAA

Upstream 100 bases:

>100_bases
GAATCCGGATTAGCAGCCAATGTGCCATTGCGGGGTGTTTTCGTTCAGGACTACGACTCCCACACACAACCAAAGCTAAC
TAACAGGAGAATCCAGATGG

Downstream 100 bases:

>100_bases
CTTATTGATTTAAATGGTGCCGATAATAGGAGTCGAACCTACGACCTTCGCATTACGAATGCGCTGCTCTACCAACTGAG
CTATATCGGCCCTGAAAGGA

Product: integrase

Products: NA

Alternate protein names: Prophage QSR' integrase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASV
ATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLE
WQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEG
TNDV

Sequences:

>Translated_324_residues
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASV
ATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLE
WQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEG
TNDV
>Mature_324_residues
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASV
ATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLE
WQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEG
TNDV

Specific function: Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1786748, Length=298, Percent_Identity=71.4765100671141, Blast_Score=466, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37389; Mature: 37389

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EACRKKGKPVPEYTPKPASVATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
RWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLEWQQIDMQRRVAWINPEESKS
EECCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHHEECCCCCCCC
NRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
CCEEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHH
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQ
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHH
IDSILNPSVPNLSQSKNKEGTNDV
HHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EACRKKGKPVPEYTPKPASVATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
RWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLEWQQIDMQRRVAWINPEESKS
EECCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHHEECCCCCCCC
NRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
CCEEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHH
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQ
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHH
IDSILNPSVPNLSQSKNKEGTNDV
HHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2553674; 2183007; 9278503 [H]