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The map label for this gene is gatY [H]

Identifier: 209396937

GI number: 209396937

Start: 2846686

End: 2847540

Strand: Reverse

Name: gatY [H]

Synonym: ECH74115_3075

Alternate gene names: 209396937

Gene position: 2847540-2846686 (Counterclockwise)

Preceding gene: 209396214

Following gene: 209400959

Centisome position: 51.1

GC content: 53.1

Gene sequence:

>855_bases
ATGTACGTGGTATCGACAAAGCAGATGCTGAACAACGCGCAGCGCGGCGGTTACGCGGTTCCGGCATTCAATATTCACAA
TCTCGAAACGATGCAAGTGGTGGTAGAAACCGCTGCCAACCTGCATGCGCCGGTCATCATCGCCGGAACGCCTGGCACAT
TTACTCATGCTGGTACAGAAAATCTGTTGGCGCTGGTCAGCGCGATGGCGAAGCATTATCACCATCCACTGGCGATTCAT
CTCGACCATCACACGAAATTTGACGATATCGCTCAGAAGGTTCGTTCTGGCGTGCGCTCAGTCATGATTGACGCCTCGCA
TTTGCCTTTTGCGCAAAATATTTCACGGGTCAAAGAGGTGGTGGATTTTTGCCATCGCTTTGATGTCAGCGTCGAAGCGG
AGCTGGGGCAACTTGGCGGCCAGGAAGATGATGTGCAAGTCAATGAAGCCGATGCTTTTTATACCAACCCCGCTCAGGCG
CGTGAATTTGCCGAGGCAACCGGAATTGATTCCCTGGCGGTCGCCATCGGCACGGCTCATGGTATGTATGCCAGCGCACC
GGCGCTTGATTTTTCTCGACTGGAGAACATTCGCCAGTGGGTGAACTTACCGCTGGTGCTGCATGGCGCGTCAGGGTTAT
CGACTAAGGATATTCAGCAAACCATCAAACTGGGGATATGCAAAATCAACGTTGCAACGGAGCTGAAAAATGCCTTCTCG
CAGGCGTTAAAAAATTACCTGACCGAGCACCCCGAAGCGACCGATCCCCGGGATTATTTGCAGTCGGCTAAATCCGCAAT
GCGCGATGTGGTGAGCAAAGTGATTGCCGATTGTGGCTGCGAGGGCAGGGCATAA

Upstream 100 bases:

>100_bases
TTAATTTTCATATTGTCGTTTTTGTGATCGTTATCTCGACATTTAAAAACAAATGATTTCATTATGTTTTGAAATCGAAA
GCAATCGACAGGATGTGAAA

Downstream 100 bases:

>100_bases
CGCACCTGCCATTTAACAAGGAAAAAACATGAAAACGTTAATTGCCCGGCATAAAGCTGGTGAACATATCGGCATATGTT
CAGTCTGTTCTGCCCATCCG

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKHYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA

Sequences:

>Translated_284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKHYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
>Mature_284_residues
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKHYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=284, Percent_Identity=99.2957746478873, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=55.1236749116608, Blast_Score=335, Evalue=1e-93,
Organism=Escherichia coli, GI1788072, Length=234, Percent_Identity=42.3076923076923, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789293, Length=324, Percent_Identity=24.3827160493827, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=329, Percent_Identity=24.0121580547112, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 30855; Mature: 30855

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTE
CEEECHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
NLLALVSAMAKHYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEEECCCCEECCHHHHHHHHHHHCCHHHHHHHHHHC
GMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHH
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTE
CEEECHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
NLLALVSAMAKHYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCCEEECCCCEECCHHHHHHHHHHHCCHHHHHHHHHHC
GMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHH
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA