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The map label for this gene is wecF [H]

Identifier: 209396700

GI number: 209396700

Start: 4874027

End: 4875106

Strand: Direct

Name: wecF [H]

Synonym: ECH74115_5226

Alternate gene names: 209396700

Gene position: 4874027-4875106 (Clockwise)

Preceding gene: 209395930

Following gene: 209397845

Centisome position: 87.47

GC content: 52.87

Gene sequence:

>1080_bases
ATGACTGTACTGATTCACGTACTGGGATCGGATATCCCTCACCATAACCGAACCGTTTTGCGGTTTTTCAATGACGCGCT
GGCCGCGACGAGCGAGCACGCGCGCGAGTTTATGGTTGTTGGCAAGGACGACGGCTTAAGTGATAGCTGTCCGGCGCTTT
CTGTGCAATTTTTCCCTGGGAAAAAATCGCTGGCGGAAGCGGTCATCGCGAAAGCAAAAGCTAACCGTCAGCAGCGTTTT
TTCTTCCACGGTCAGTTCAATCCCACACTGTGGCTGGCTCTGCTGAGTGGTGGCATTAAGCCCAGCCAGTTTTACTGGCA
TATCTGGGGGGCAGACCTGTACGAGCTTTCCAGTGGCTTGAGATATAAGCTTTTTTACCCACTACGTCGCCTGGCGCAAA
AGCGAGTCGGCTGTGTATTTGCCACCCGTGGTGATTTGAGCTTTTTTGCCAAAACGCACCCAAAGGTGCGGGGCGAACTG
CTGTACTTCCCGACGCGGATGGATGCTTCTCTCAATACGATGGCGAACGATCGGCAACGTGAAGGGAAAATGACCATTCT
GGTGGGGAACTCCGGCGACCGCAGCAATGAGCATATTGCTGCCTTGCGCGCCGTTCATCAGCAATTTGGCGATACGGTAA
AAGTGGTGGTGCCGATGGGATATCCGCCTCATAACGAAGCGTACATCGAGGAAGTTCGTCAGGCGGGGCTGGAGTTATTC
AGCGAAGAAAATCTGCAAGTTCTGAGTGAAAAACTGGAATTTGACGCCTATCTGACGCTACTTCGTCAGTGCGATCTTGG
TTACTTTATTTTTGCCCGCCAGCAGGGCATTGGTACGCTGTGCTTACTGATTCAGGCGGGCATTCCTTGTGTGCTTAACC
GGGAAAATCCGTTCTGGCAGGATATGACGGAACAGCATTTACCGGTGCTGTTTACTACCGACGATCTCAACGAGGATATT
GTGCGTGAAGCGCAGCGCCAGTTGGCGTCGGTGGATAAAAACACCATTGCCTTCTTTAGCCCTAACTATCTACAAGGCTG
GCAGCGGGCGTTGGCGATTGCCGCCGGGGAGGTCGCATGA

Upstream 100 bases:

>100_bases
CTACGCACGGCGCGCTGGGCGCGGCACAGGCATATATGGCAACCTATATCGTCTATTTTTCTCTTTGTTGTGGCGTGTTT
TTACTCTGGCGTAGGCGGGC

Downstream 100 bases:

>100_bases
GTCTGCTGCAATTCAGTGGCCTGTTTGTTGTCTGGCTGCTCTGCACGCTGTTTATTGCCACGCTGACCTGGTTTGAGTTT
CGTCGTGTGCGCTTTAACTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRF
FFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
LYFPTRMDASLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELF
SEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDI
VREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA

Sequences:

>Translated_359_residues
MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRF
FFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
LYFPTRMDASLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELF
SEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDI
VREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
>Mature_358_residues
TVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFF
FHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELL
YFPTRMDASLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELFS
EENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIV
REAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family [H]

Homologues:

Organism=Escherichia coli, GI48994971, Length=359, Percent_Identity=98.050139275766, Blast_Score=734, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009993 [H]

Pfam domain/function: PF07429 Fuc4NAc_transf [H]

EC number: NA

Molecular weight: Translated: 40586; Mature: 40455

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPG
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCC
KKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGL
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHCCCC
RYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDASLNTMANDRQR
EEEEHHHHHHHHHHHHCEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHC
EGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
SEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEECCCCCCHH
DMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPG
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCC
KKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGL
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHCCCC
RYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDASLNTMANDRQR
EEEEHHHHHHHHHHHHCEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHC
EGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
SEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEECCCCCCHH
DMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA