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The map label for this gene is speB [H]

Identifier: 209396386

GI number: 209396386

Start: 3927885

End: 3928805

Strand: Reverse

Name: speB [H]

Synonym: ECH74115_4239

Alternate gene names: 209396386

Gene position: 3928805-3927885 (Counterclockwise)

Preceding gene: 209397312

Following gene: 209400304

Centisome position: 70.51

GC content: 55.16

Gene sequence:

>921_bases
ATGAGCACCTTAGGTCATCAATACGATAACTCACTGGTTTCCAACGCCTTTGGTTTTTTGCGCCTGCCGATGAACTTCCA
GCCGTATGACAGCGATGCTGACTGGGTGATTACTGGTGTGCCGTTCGATATGGCCACTTCTGGTCGTGCGGGGGGACGCC
ACGGTCCGGCAGCTATCCGTCAGGTTTCGACGAATCTGGCCTGGGAACACAACCGCTTCCCGTGGAATTTCGACATGCGT
GAGCGTCTGAACGTCGTGGACTGTGGTGATCTGGTATATGCTTTCGGCGATGCCCGTGAGATGAGCGAGAAGCTGCAGGC
GCACGCCGAGAAGCTGCTGGCTGCCGGTAAGCGTATGCTCTCCTTCGGTGGTGACCACTTTGTTACGCTGCCGCTGCTGC
GTGCTCATGCGAAGCATTTCGGCAAAATGGCGCTGGTACACTTTGACGCCCACACCGATACCTACGCGAACGGTTGTGAA
TTTGACCACGGCACCATGTTCTATACCGCGCCGAAAGAAGGTCTGATCGACCCGAATCATTCCGTGCAGATTGGTATTCG
TACCGAATTTGATAAAGACAACGGCTTTACCGTGCTGGACGCCTGCCAGGTGAACGATCGCAGCGTGGATGACGTTATCG
CCCAGGTGAAACAAATTGTGGGTGATATGCCGGTTTACCTGACCTTTGATATCGACTGCCTGGATCCTGCATTTGCGCCG
GGAACCGGTACGCCGGTAATTGGCGGTCTGACCTCCGATCGCGCTATTAAACTGGTACGCGGCCTGAAAGATCTCAACAT
CGTTGGGATGGACGTAGTGGAAGTGGCTCCGGCATACGATCAGTCGGAAATCACCGCTCTGGCAGCGGCAACGCTGGCGC
TGGAAATGCTGTATATTCAGGCGGCGAAAAAGGGCGAGTAA

Upstream 100 bases:

>100_bases
AATTAGCACAAACTTGTGTTTCGCAAATCCAACCCTTCCTCGTCGGGCCTAACGACGCGGAAGGGTTTTTTTATATCGAC
TTTGTAATAGGAGTCCATCC

Downstream 100 bases:

>100_bases
GCACCAGATGCGATGCGCACGGGTAAAACGTGCCATTAATGTCGGATGCGGCGTGAACGCCTTATCCGACCTACGTTCGG
CACCCGTAGGCCGGATAAGA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMR
ERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAP
GTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE

Sequences:

>Translated_306_residues
MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMR
ERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAP
GTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
>Mature_305_residues
STLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRE
RLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEF
DHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPG
TGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=292, Percent_Identity=41.0958904109589, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI4502215, Length=314, Percent_Identity=26.4331210191083, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789306, Length=306, Percent_Identity=100, Blast_Score=636, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996843, Length=294, Percent_Identity=22.108843537415, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33557; Mature: 33426

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIR
CCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRML
HHHHCCCEECCCCCCCCCHHHCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNH
HCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAP
CEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
GTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKKGE
HHCCCC
>Mature Secondary Structure 
STLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIR
CCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRML
HHHHCCCEECCCCCCCCCHHHCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNH
HCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAP
CEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
GTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKKGE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA