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The map label for this gene is artM

Identifier: 209396120

GI number: 209396120

Start: 1032826

End: 1033494

Strand: Reverse

Name: artM

Synonym: ECH74115_1021

Alternate gene names: 209396120

Gene position: 1033494-1032826 (Counterclockwise)

Preceding gene: 209398007

Following gene: 209396948

Centisome position: 18.55

GC content: 52.91

Gene sequence:

>669_bases
ATGTTTGAGTATTTACCCGAACTGATGAAAGGGCTGCACACCAGCCTGACGCTAACCGTTGCCTCGCTGATTGTGGCACT
GATTCTGGCGTTGATTTTTACCATCATCCTGACGCTGAAAACGCCGGTGCTGGTGTGGCTGGTGCGGGGTTATATCACGC
TGTTTACCGGTACACCGCTGCTGGTGCAGATCTTCCTGATTTATTACGGGCCGGGTCAGTTCCCGACGTTGCAGGAGTAT
CCGGCACTGTGGCATTTGTTGTCAGAACCGTGGTTATGTGCGCTGATTGCGTTGTCGCTGAACAGTGCGGCGTATACCAC
GCAGCTGTTTTACGGTGCAATTCGTGCGATCCCGGAAGGTCAGTGGCAGTCCTGTAGCGCCCTGGGAATGAGCAAAAAAG
ATACGCTGGCGATCCTGCTGCCGTATGCCTTTAAACGCTCGCTCTCTTCTTATTCCAACGAAGTGGTGCTGGTGTTCAAA
AGTACCTCTCTGGCTTACACCATTACGCTGATGGAAGTGATGGGATACAGCCAGTTGTTGTACGGACGCACCTACGATGT
CATGGTGTTCGGCGCGGCAGGGATTATTTATCTGGTCGTTAACGGCCTGCTGACGCTGATGATGCGTCTGATCGAGCGCA
AAGCGCTGGCGTTTGAGCGAAGGAATTAA

Upstream 100 bases:

>100_bases
TTGTGGCGGCGGCGATTTACCTGGTGATCACCCTGCTCAGTCAGTACATTCTCAAACGCATTGACCTGCGCGCGACACGT
TTTGAGCGGAGGCCCAGCTA

Downstream 100 bases:

>100_bases
TGTGGCTGCGTACATTCGCCGGGGGTTTTGTAGGTCTGATAAGACGCGCCAGCGTCGCATCAGACATCAGCACGGTGCCT
GTGCCGGATGCGGCGTGGAC

Product: arginine transporter permease subunit ArtM

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN

Sequences:

>Translated_222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
>Mature_222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN

Specific function: Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787086, Length=222, Percent_Identity=100, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=33.4841628959276, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=31.7307692307692, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787087, Length=237, Percent_Identity=29.535864978903, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=26.2910798122066, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788646, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786874, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1786873, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARTM_ECO57 (P0AE32)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D85597
- PIR:   H90746
- RefSeq:   NP_286630.1
- RefSeq:   NP_308971.1
- ProteinModelPortal:   P0AE32
- EnsemblBacteria:   EBESCT00000024829
- EnsemblBacteria:   EBESCT00000057013
- GeneID:   917725
- GeneID:   958255
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1091
- KEGG:   ecs:ECs0944
- GeneTree:   EBGT00050000008884
- HOGENOM:   HBG704821
- OMA:   IVRAYIT
- ProtClustDB:   PRK11122
- BioCyc:   ECOL83334:ECS0944-MONOMER
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24914; Mature: 24914

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x24d99dd0)-; HASH(0x2386c6a8)-; HASH(0x260cd76c)-; HASH(0x25f78aa8)-; HASH(0x2605b9bc)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
HCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
HCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796