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The map label for this gene is LytS2 [H]

Identifier: 20808710

GI number: 20808710

Start: 2229641

End: 2231422

Strand: Reverse

Name: LytS2 [H]

Synonym: TTE2344

Alternate gene names: 20808710

Gene position: 2231422-2229641 (Counterclockwise)

Preceding gene: 20808716

Following gene: 20808709

Centisome position: 82.97

GC content: 34.01

Gene sequence:

>1782_bases
ATGGTTTTAAAGCTTAAGAATTGGTTTATGGGGCTTAATATAAGGCATAAAATTTTAATCTTGTTTTACGGGATAGTCGT
CATTACATCCTTGTTAATTGTGTTTTTTTCTTACACTATCTCAATAAACCAGCTTAAAAAAGAGGTAGGGAATTCACTTT
TAAGAGATACAAAGAGAATTGCAGCAAGCATTGATTTTCTGCAAAGGGATGTCAATGAGCTTTCTTCCTTTCTGGTTTTG
GACCAGAGGATTCAGAACTTCATAAGTCCTCATTCCGATTTTACCAAGTATTCCCTTGGACCGCTAGCCAGTTTACTTGC
TTCCAAAGATTATATAAGCTTTATAGCTTTGTATTCCTTTCAAGGGGACAAATATTATTTTTCCAATGACAGCAGTACTT
TAATAATGGATTTAGAACTTATTAAAAGAACCAGCTTTTACAGAGAAGTGTTAGAGAAAAATGGTGCTCCTATGTGGCTA
AGTTTGGAAAATTTGCCTTTTGACTTAATAATCAAAAACAATTACCCTAAAATTGCTATGGCAAGGGTGCTTTTGGATTT
TAATACATACAAGCCGGAGGGCTTATTGGTAATATGTATAAACATACCTACAATTGAAAAGGTTTATTCTGAAAACTTAA
AAGAAAAAGAGTCTGCCTTTTTCATAGCAGACAGAAATGGAAATATAATATCTTTTAAGAGCACTTTCTCAGGGTTTACT
CCAAAATCGGCTCAAAATATACTCGCAAAATACCTTAAAGATAAGCAAAATGTGGTGATAAATATAAATTCATCCAAACT
CCTTGTGACGTCAAGTCCGATACCTACTTCTGATTGGAGGCTTGTAAGCGTTGTCTCTTTAAAAAATGCCATTAATTCTA
TAAGAATTTCTTTTATTGAGTTTTACTTGAGGATATTAGTTTTTTGTCTGCTTTTTGCTTTTCTGGTTTCCATGTATTTT
TCAAGGGCTTTAACTCATCCATTGGAAAGGCTGGCTAATTCCATGAAGAAGGTCAGGCAGGGAAATTTGGAAGAAAAGGT
GGAGTTTGAATATCATTCAAAGGATGAGATTGCTATAGTTATAAAGGAATACAATAGAATGGTTGAGAGGATAAACGACC
TTATTAATAGGATTTTAAAACTGGAAATCAATAAAAGAGAAGCGGAGTTAAAGGCGCTGGAAGCTCAGATTAACCCACAT
TTTCTGTACAACACTTTGGATACTATTTTTTGGAAAGCCGAGAAGGCGAAGGATAGGGAACTCAGTGAGATGATTTACTC
TCTTTCTCGGCTTTTCAGACTCACTTTAAACAGGGGTGAGGAATTTATACAGGTAAGGGGAGAAAAAGAGCTTATAGAAA
GGTATTTATTCTTGCAGAGCAAGAGATATAAGAATAAATTTAAATATTCTGTAAAAATTTCCGATGAAATTTTGGATTAT
TATATACCAAAGCTTATTCTTCAACCTTTTGTAGAGAATGCCATTGTGCACGGATTGGAAAACAATTCGGAGGAGAGTTT
TGTGGAAGTGATAGGTGAAAAAGAAGGGGAAAATTTAAAGTTTATCATTAAGGACAATGGGCCTGGCATGTCAGAAGAGA
CTTTAGAAAAGTTAAAAAGATTTATAGAATCAGAGAATATTGAAGAAAAAGTGGGATATGCGATTAGAAATGTAAATGAG
AGGTTAAGGCTTTATTATGGAGATAAGTATGAGCTTAAAATAGAGAGTAGGCAAGGAGAAGGGACAACCATTTCCCTTAT
ATTGCCTGAAAGTATATCTTAA

Upstream 100 bases:

>100_bases
ATTTGGTTTGTAATTTTTATGTATTTTTGTAAAGGTTGAAGGCAAAAAGATTTTAGTTGTATAATAAATCTACAGGAAAT
TTTGAAAGGATGTACATAGG

Downstream 100 bases:

>100_bases
GGGGGAGGGCGTATGAAGCTATTTATAGCCGATGATGAAGTGGAGGTTGTGGAGGGAATTTTGACACTTATTGATTGGAA
AGGGAATGGGATTGAACTTG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MVLKLKNWFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRIAASIDFLQRDVNELSSFLVL
DQRIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSFQGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWL
SLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFT
PKSAQNILAKYLKDKQNVVININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIEFYLRILVFCLLFAFLVSMYF
SRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPH
FLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDY
YIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNE
RLRLYYGDKYELKIESRQGEGTTISLILPESIS

Sequences:

>Translated_593_residues
MVLKLKNWFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRIAASIDFLQRDVNELSSFLVL
DQRIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSFQGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWL
SLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFT
PKSAQNILAKYLKDKQNVVININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIEFYLRILVFCLLFAFLVSMYF
SRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPH
FLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDY
YIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNE
RLRLYYGDKYELKIESRQGEGTTISLILPESIS
>Mature_593_residues
MVLKLKNWFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRIAASIDFLQRDVNELSSFLVL
DQRIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSFQGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWL
SLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFT
PKSAQNILAKYLKDKQNVVININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIEFYLRILVFCLLFAFLVSMYF
SRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPH
FLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDY
YIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNE
RLRLYYGDKYELKIESRQGEGTTISLILPESIS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=204, Percent_Identity=32.3529411764706, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788723, Length=216, Percent_Identity=29.6296296296296, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69034; Mature: 69034

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKLKNWFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRI
CEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASIDFLQRDVNELSSFLVLDQRIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHEEEE
QGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWLSLENLPFDLIIKNNYPKIAM
CCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCHHHH
ARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFT
HHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCC
PKSAQNILAKYLKDKQNVVININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIE
CCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
FYLRILVFCLLFAFLVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
IKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCHH
LSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDY
HHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
YIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
FIESENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILPESIS
HHCCCCHHHHHHHHHHCCCHHEEEEECCEEEEEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MVLKLKNWFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRI
CEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASIDFLQRDVNELSSFLVLDQRIQNFISPHSDFTKYSLGPLASLLASKDYISFIALYSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHEEEE
QGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWLSLENLPFDLIIKNNYPKIAM
CCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCHHHH
ARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKSTFSGFT
HHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCC
PKSAQNILAKYLKDKQNVVININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFIE
CCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
FYLRILVFCLLFAFLVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
IKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCHH
LSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDY
HHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
YIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
FIESENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILPESIS
HHCCCCHHHHHHHHHHCCCHHEEEEECCEEEEEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]