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The map label for this gene is fchA [H]

Identifier: 20806964

GI number: 20806964

Start: 469349

End: 470065

Strand: Direct

Name: fchA [H]

Synonym: TTE0456

Alternate gene names: 20806964

Gene position: 469349-470065 (Clockwise)

Preceding gene: 20806962

Following gene: 20806965

Centisome position: 17.45

GC content: 37.24

Gene sequence:

>717_bases
TTGTTACAAAGGTTCGCGTTTATTGGTATAATAAGTGGTGTGAAAACATTTGAGAAGGGAGATGGTGTTGTGCTAATCAA
TGATTCTTTAAAAGGGTATATTGAAAAGGTTGCCTCAGCTTCACCTACGCCGGGTGGTGGAAGTGTTTCGGCAGCGGCTG
CAAGCCTTGGAATTGCTCTATCAAAAATGGTTTACGATTTGACTATTGGGAGGAAATTTTATGAAGAGTATTCAGAGGAC
ATAAAAGAAGAGATTCAAGAAGGACTTAATATTTGCAATAGGCTTTTAGAGGAATACATGAAGCTTGTAGATGAGGATAC
AGCTGCTTATGATGAAGTTATGAAAGCTTTAAAAATGCCAAAAAATACGGAGGAAGAAAAGAAGATAAGAAGTGAGGTTT
TGCAGAAGGCATACATAAATGCAATGAATGTTCCTTTAAAACTTGCAAGACTTTGCGGCGAAGGATTTACTCCCACTGCT
TTAATTGCTGAGTATGGCAATCCCAACGCTGTATCAGATGCAGCTGTTGGTGCAATACTATTATATGCAGCTATGGAAGG
AGCAGTTTTGAATGTAAAGGTCAATCTACCTTATATCAAGGATAAAAAGCTTGCCGAAGAGGCTAAAAAAGAGTGCGATG
AATTACTCAATAAATATAGAAGTGTGAGGAATGAGATTGTAAGTAAAGTATTGAATAAAATTTCTGGGGAATACTAA

Upstream 100 bases:

>100_bases
GAGTTCTAGGGTCTCTGTACAGAAGTTCTTTTATTATGTCTATGTCCCCTGTTGACAACGCCAATATTAAAAAATGAAAC
AAAGTTAGGAGTTGACAATT

Downstream 100 bases:

>100_bases
AAAAATAATTGTGGAAGATATCTAAAGAGAGGAGGCGATTTTTAGAGAAAATATATAAGTTATAAAGAAAAACAGGGTTA
TTTGAGAGTTGTATATGAAA

Product: Methenyl tetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLQRFAFIGIISGVKTFEKGDGVVLINDSLKGYIEKVASASPTPGGGSVSAAAASLGIALSKMVYDLTIGRKFYEEYSED
IKEEIQEGLNICNRLLEEYMKLVDEDTAAYDEVMKALKMPKNTEEEKKIRSEVLQKAYINAMNVPLKLARLCGEGFTPTA
LIAEYGNPNAVSDAAVGAILLYAAMEGAVLNVKVNLPYIKDKKLAEEAKKECDELLNKYRSVRNEIVSKVLNKISGEY

Sequences:

>Translated_238_residues
MLQRFAFIGIISGVKTFEKGDGVVLINDSLKGYIEKVASASPTPGGGSVSAAAASLGIALSKMVYDLTIGRKFYEEYSED
IKEEIQEGLNICNRLLEEYMKLVDEDTAAYDEVMKALKMPKNTEEEKKIRSEVLQKAYINAMNVPLKLARLCGEGFTPTA
LIAEYGNPNAVSDAAVGAILLYAAMEGAVLNVKVNLPYIKDKKLAEEAKKECDELLNKYRSVRNEIVSKVLNKISGEY
>Mature_238_residues
MLQRFAFIGIISGVKTFEKGDGVVLINDSLKGYIEKVASASPTPGGGSVSAAAASLGIALSKMVYDLTIGRKFYEEYSED
IKEEIQEGLNICNRLLEEYMKLVDEDTAAYDEVMKALKMPKNTEEEKKIRSEVLQKAYINAMNVPLKLARLCGEGFTPTA
LIAEYGNPNAVSDAAVGAILLYAAMEGAVLNVKVNLPYIKDKKLAEEAKKECDELLNKYRSVRNEIVSKVLNKISGEY

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=204, Percent_Identity=32.843137254902, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI11140815, Length=204, Percent_Identity=32.843137254902, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 26133; Mature: 26133

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRFAFIGIISGVKTFEKGDGVVLINDSLKGYIEKVASASPTPGGGSVSAAAASLGIAL
CCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SKMVYDLTIGRKFYEEYSEDIKEEIQEGLNICNRLLEEYMKLVDEDTAAYDEVMKALKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KNTEEEKKIRSEVLQKAYINAMNVPLKLARLCGEGFTPTALIAEYGNPNAVSDAAVGAIL
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHH
LYAAMEGAVLNVKVNLPYIKDKKLAEEAKKECDELLNKYRSVRNEIVSKVLNKISGEY
HHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQRFAFIGIISGVKTFEKGDGVVLINDSLKGYIEKVASASPTPGGGSVSAAAASLGIAL
CCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SKMVYDLTIGRKFYEEYSEDIKEEIQEGLNICNRLLEEYMKLVDEDTAAYDEVMKALKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KNTEEEKKIRSEVLQKAYINAMNVPLKLARLCGEGFTPTALIAEYGNPNAVSDAAVGAIL
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHH
LYAAMEGAVLNVKVNLPYIKDKKLAEEAKKECDELLNKYRSVRNEIVSKVLNKISGEY
HHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]