BacMap

Definition	Thermoanaerobacter tengcongensis MB4, complete genome.
Accession	NC_003869
Length	2,689,445

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The map label for this gene is msbA [H]

Identifier: 20806906

GI number: 20806906

Start: 416719

End: 417051

Strand: Direct

Name: msbA [H]

Synonym: TTE0396

Alternate gene names: 20806906

Gene position: 416719-417051 (Clockwise)

Preceding gene: 20806905

Following gene: 20806907

Centisome position: 15.49

GC content: 40.24

Gene sequence:

>333_bases
GTGGAAGCCTTGAAAAAAGCAGGACTATTGGACTGGTTTAAAGAGCTGCCGGAGGGCTTTGATACTAAAATAGGACAGAC
AAGAAAGCTTATTTCAGGAGGAGAACGGTCGAGATTGTCAATTGCAAGGATGATTTTGTTTGACCCGGAAATCCTTCTGC
TGGATGAGCCGTTAGTGGGAGTAGACCAGGAAAGAAAGGAGGAAATATTTGATACACTGAAAGAACTGCTAAAAAGCAAA
ACCTGCATTTTGGTTACTCATGACAAGAGTTTATTGAGAATTGCTGACAGGACAATATATATGAAAGAGGAAGATGCAGT
ATGGCTAATATAA

Upstream 100 bases:

>100_bases
ATATAATAGCTGTTTAGATATGCTATCTAATTTACAATAAATCCCTTCAAATGCAGAATCACTTCGGGTTGCAAAGCCTG
ATGCTTCCGAGGAAGAACTG

Downstream 100 bases:

>100_bases
AGTGGGTGTTTCGCTCAATAAATAAAACTCTTCTAATAAACTTTTTTGCTGTTTTTTCCGTATATTTGCTTTAATATTGC
CATTACTTTACGGACAGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MEALKKAGLLDWFKELPEGFDTKIGQTRKLISGGERSRLSIARMILFDPEILLLDEPLVGVDQERKEEIFDTLKELLKSK
TCILVTHDKSLLRIADRTIYMKEEDAVWLI

Sequences:

>Translated_110_residues
MEALKKAGLLDWFKELPEGFDTKIGQTRKLISGGERSRLSIARMILFDPEILLLDEPLVGVDQERKEEIFDTLKELLKSK
TCILVTHDKSLLRIADRTIYMKEEDAVWLI
>Mature_110_residues
MEALKKAGLLDWFKELPEGFDTKIGQTRKLISGGERSRLSIARMILFDPEILLLDEPLVGVDQERKEEIFDTLKELLKSK
TCILVTHDKSLLRIADRTIYMKEEDAVWLI

Specific function: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=99, Percent_Identity=37.3737373737374, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI255708477, Length=101, Percent_Identity=34.6534653465347, Blast_Score=72, Evalue=7e-14,
Organism=Homo sapiens, GI21536378, Length=103, Percent_Identity=35.9223300970874, Blast_Score=72, Evalue=8e-14,
Organism=Homo sapiens, GI148612844, Length=101, Percent_Identity=34.6534653465347, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI9961250, Length=95, Percent_Identity=35.7894736842105, Blast_Score=71, Evalue=1e-13,
Organism=Homo sapiens, GI4505771, Length=95, Percent_Identity=35.7894736842105, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI9961252, Length=95, Percent_Identity=35.7894736842105, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI42741659, Length=95, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI9955963, Length=101, Percent_Identity=35.6435643564356, Blast_Score=68, Evalue=1e-12,
Organism=Homo sapiens, GI171184400, Length=90, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Homo sapiens, GI9955970, Length=105, Percent_Identity=38.0952380952381, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI66529005, Length=89, Percent_Identity=40.4494382022472, Blast_Score=67, Evalue=4e-12,
Organism=Homo sapiens, GI89111135, Length=103, Percent_Identity=34.9514563106796, Blast_Score=65, Evalue=8e-12,
Organism=Homo sapiens, GI134142335, Length=101, Percent_Identity=38.6138613861386, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI134142337, Length=101, Percent_Identity=38.6138613861386, Blast_Score=64, Evalue=2e-11,
Organism=Homo sapiens, GI156105685, Length=106, Percent_Identity=29.2452830188679, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787143, Length=102, Percent_Identity=36.2745098039216, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1786653, Length=96, Percent_Identity=36.4583333333333, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1788225, Length=75, Percent_Identity=40, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=86, Percent_Identity=37.2093023255814, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=73, Percent_Identity=42.4657534246575, Blast_Score=60, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=107, Percent_Identity=36.4485981308411, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558664, Length=100, Percent_Identity=38, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115535101, Length=99, Percent_Identity=34.3434343434343, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567269, Length=103, Percent_Identity=33.0097087378641, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17569145, Length=110, Percent_Identity=33.6363636363636, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17541710, Length=95, Percent_Identity=35.7894736842105, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193211017, Length=105, Percent_Identity=34.2857142857143, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=105, Percent_Identity=34.2857142857143, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71996809, Length=105, Percent_Identity=34.2857142857143, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=100, Percent_Identity=34, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17569143, Length=92, Percent_Identity=35.8695652173913, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=107, Percent_Identity=33.6448598130841, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569081, Length=106, Percent_Identity=36.7924528301887, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=106, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=100, Percent_Identity=33, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=96, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=97, Percent_Identity=30.9278350515464, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556528, Length=98, Percent_Identity=36.734693877551, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=97, Percent_Identity=29.8969072164948, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17533971, Length=97, Percent_Identity=31.9587628865979, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193209740, Length=105, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17511077, Length=86, Percent_Identity=32.5581395348837, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567243, Length=91, Percent_Identity=37.3626373626374, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=102, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992070, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25146765, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86564969, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992066, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=102, Percent_Identity=32.3529411764706, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=103, Percent_Identity=32.0388349514563, Blast_Score=64, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322640, Length=103, Percent_Identity=34.9514563106796, Blast_Score=62, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=99, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363262, Length=102, Percent_Identity=35.2941176470588, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653245, Length=102, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI85726357, Length=96, Percent_Identity=36.4583333333333, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17136662, Length=101, Percent_Identity=32.6732673267327, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24659289, Length=106, Percent_Identity=34.9056603773585, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641565, Length=93, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397593, Length=102, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221460257, Length=103, Percent_Identity=35.9223300970874, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281361582, Length=99, Percent_Identity=37.3737373737374, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011917
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 12717; Mature: 12717

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALKKAGLLDWFKELPEGFDTKIGQTRKLISGGERSRLSIARMILFDPEILLLDEPLVG
CCHHHHCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCC
VDQERKEEIFDTLKELLKSKTCILVTHDKSLLRIADRTIYMKEEDAVWLI
CCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCEEEEECCCCEEEC
>Mature Secondary Structure
MEALKKAGLLDWFKELPEGFDTKIGQTRKLISGGERSRLSIARMILFDPEILLLDEPLVG
CCHHHHCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCC
VDQERKEEIFDTLKELLKSKTCILVTHDKSLLRIADRTIYMKEEDAVWLI
CCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA