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The map label for this gene is norA [H]

Identifier: 20094564

GI number: 20094564

Start: 1102596

End: 1103690

Strand: Reverse

Name: norA [H]

Synonym: MK1128

Alternate gene names: 20094564

Gene position: 1103690-1102596 (Counterclockwise)

Preceding gene: 20094567

Following gene: 20094562

Centisome position: 65.12

GC content: 70.41

Gene sequence:

>1095_bases
GTGAGGCCGTTGATCGCACACGTCGTGGGCATCGCGTGCGCGGTGTCCCTGACATCAGTCCTGCCGATCCTCCCGCTCTA
CGTGGTGGACGCGGGCTACCCCCGCTCGTTCGTCGGCGTCATGAACCTCGTACACAACGTGACGCAGCTCCTAGCCAGGC
CCGTCGGAGGGGCCCTGACGGACGCGTACGGTCCCAGGAGGCTCGCGCCGCTCGGGGCCCTAGGGTACGCGCTGTCCGAC
CTGCTGGTTCTCGTCCCGCACCCCGGGACGCTGCTGGCCAGCCGAGTTTCCCTGGGTCTCGGTATGGGCGCGCTCTGGCC
GCCGCTCCTGTCCACCGTCGCGGACAGCGGTCGCTCCCTGGGCGTCTTCAACGCGGTCACCCAGCTTCCGATGGTCCTGG
CTCCGCCCCTGGGGGGCTACCTCTACCGGAGCGTCGGACCCTGGGCCTTCGCCGTCCTCGCGTTACCGGCACTGCTCGCC
GTACCGCTGGCGGGATCGCTCCCGGACGTCCGGACGTCCCGGGAGAAGGTCTCACCCCTCGAGGTGTTGAAGAGATCGCT
AGAGGTCGACCGGGAGCTCTTCCGGGCCTCGCTCCCCGCGTTCGCCACCGCGGCCGTGCAACCAACGATCGAGTCGTTCG
TCCCGCTGCTGCTGAAGAAGCTCGGCGCGGACCCGGCACAGATCGGACTGGTACTCGCGATCCGCAACGCCGTGGCGGTG
ACCCTGCAGGCGCCGTGCGGGTGGCTGGCCGACCGGTACAGCCCGACCGTCCTGGCCGCGCTGGGGTGCGTGCTCGCCGC
CCTGGGCGTGCTGGTGCTGCCCTTCGTGGAGAGCGTACCCGTCGCCGTGGTCCTGCTGTGCGTGGGAGGGGTCGGGTACT
CGCTGGCCCAACCGTCATCGCTCAAGCTGGTGGCGGAGGTCTCCGGGGAGAGACGCGGCCTCGGGATGGGATGGTGGGGC
TCGATCATGTCCCTCGGGAGGCTCACCGGGTCCCTGCCCGGGCTGCTGGCGGACGTCTCGCTCAGCGCCGTGTTCTACAT
CTCCGGTGCGATCCCACTGGCGAGCGTCCTCCCGCTGCTCCGACGCCCTCGATGA

Upstream 100 bases:

>100_bases
CGTGTGAACTGAATTAAAAGTATTCAACAAAAATATTCAACCGGGAGTCCCGCACGACCGGAGACCATCCGCGGCGTCCG
GGATCCACCGCGTAACACGG

Downstream 100 bases:

>100_bases
TCCCGCACGGTCCTCGTACCCTCGGCACGCCGAACGCTGTGAGGGGACCGTACCGGAACAGGGTAGTATCCCACGGCCCG
ACCGATCGAACCGGTCAAGG

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRPLIAHVVGIACAVSLTSVLPILPLYVVDAGYPRSFVGVMNLVHNVTQLLARPVGGALTDAYGPRRLAPLGALGYALSD
LLVLVPHPGTLLASRVSLGLGMGALWPPLLSTVADSGRSLGVFNAVTQLPMVLAPPLGGYLYRSVGPWAFAVLALPALLA
VPLAGSLPDVRTSREKVSPLEVLKRSLEVDRELFRASLPAFATAAVQPTIESFVPLLLKKLGADPAQIGLVLAIRNAVAV
TLQAPCGWLADRYSPTVLAALGCVLAALGVLVLPFVESVPVAVVLLCVGGVGYSLAQPSSLKLVAEVSGERRGLGMGWWG
SIMSLGRLTGSLPGLLADVSLSAVFYISGAIPLASVLPLLRRPR

Sequences:

>Translated_364_residues
MRPLIAHVVGIACAVSLTSVLPILPLYVVDAGYPRSFVGVMNLVHNVTQLLARPVGGALTDAYGPRRLAPLGALGYALSD
LLVLVPHPGTLLASRVSLGLGMGALWPPLLSTVADSGRSLGVFNAVTQLPMVLAPPLGGYLYRSVGPWAFAVLALPALLA
VPLAGSLPDVRTSREKVSPLEVLKRSLEVDRELFRASLPAFATAAVQPTIESFVPLLLKKLGADPAQIGLVLAIRNAVAV
TLQAPCGWLADRYSPTVLAALGCVLAALGVLVLPFVESVPVAVVLLCVGGVGYSLAQPSSLKLVAEVSGERRGLGMGWWG
SIMSLGRLTGSLPGLLADVSLSAVFYISGAIPLASVLPLLRRPR
>Mature_364_residues
MRPLIAHVVGIACAVSLTSVLPILPLYVVDAGYPRSFVGVMNLVHNVTQLLARPVGGALTDAYGPRRLAPLGALGYALSD
LLVLVPHPGTLLASRVSLGLGMGALWPPLLSTVADSGRSLGVFNAVTQLPMVLAPPLGGYLYRSVGPWAFAVLALPALLA
VPLAGSLPDVRTSREKVSPLEVLKRSLEVDRELFRASLPAFATAAVQPTIESFVPLLLKKLGADPAQIGLVLAIRNAVAV
TLQAPCGWLADRYSPTVLAALGCVLAALGVLVLPFVESVPVAVVLLCVGGVGYSLAQPSSLKLVAEVSGERRGLGMGWWG
SIMSLGRLTGSLPGLLADVSLSAVFYISGAIPLASVLPLLRRPR

Specific function: Involved in quinolone resistance. May constitute a membrane-associated active efflux pump of hydrophilic quinolones [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004734
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 37779; Mature: 37779

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLIAHVVGIACAVSLTSVLPILPLYVVDAGYPRSFVGVMNLVHNVTQLLARPVGGALT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
DAYGPRRLAPLGALGYALSDLLVLVPHPGTLLASRVSLGLGMGALWPPLLSTVADSGRSL
CCCCCCHHCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
GVFNAVTQLPMVLAPPLGGYLYRSVGPWAFAVLALPALLAVPLAGSLPDVRTSREKVSPL
HHHHHHHHCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EVLKRSLEVDRELFRASLPAFATAAVQPTIESFVPLLLKKLGADPAQIGLVLAIRNAVAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEE
TLQAPCGWLADRYSPTVLAALGCVLAALGVLVLPFVESVPVAVVLLCVGGVGYSLAQPSS
EEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LKLVAEVSGERRGLGMGWWGSIMSLGRLTGSLPGLLADVSLSAVFYISGAIPLASVLPLL
CEEHEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RRPR
HCCC
>Mature Secondary Structure
MRPLIAHVVGIACAVSLTSVLPILPLYVVDAGYPRSFVGVMNLVHNVTQLLARPVGGALT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
DAYGPRRLAPLGALGYALSDLLVLVPHPGTLLASRVSLGLGMGALWPPLLSTVADSGRSL
CCCCCCHHCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
GVFNAVTQLPMVLAPPLGGYLYRSVGPWAFAVLALPALLAVPLAGSLPDVRTSREKVSPL
HHHHHHHHCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EVLKRSLEVDRELFRASLPAFATAAVQPTIESFVPLLLKKLGADPAQIGLVLAIRNAVAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEE
TLQAPCGWLADRYSPTVLAALGCVLAALGVLVLPFVESVPVAVVLLCVGGVGYSLAQPSS
EEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LKLVAEVSGERRGLGMGWWGSIMSLGRLTGSLPGLLADVSLSAVFYISGAIPLASVLPLL
CEEHEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RRPR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA