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The map label for this gene is MiaB [C]

Identifier: 20094517

GI number: 20094517

Start: 1048183

End: 1049454

Strand: Reverse

Name: MiaB [C]

Synonym: MK1081

Alternate gene names: 20094517

Gene position: 1049454-1048183 (Counterclockwise)

Preceding gene: 20094518

Following gene: 20094515

Centisome position: 61.92

GC content: 65.41

Gene sequence:

>1272_bases
GTGACCAAGGTCGCCGTCGAGGTGTACGGGTGTGCCGCCAACCACGACGACGGTAGACTGGTGAGGGAGCTGTTACGCCG
AGAAGGTTTTGAGGTGGTCGAAGACGCTGAGAACGCGGACGTCGCCGTCCTCCTGACCTGCATCGTTCGGGACAGCGTGG
ACGCCCGAATGGTGAACAGGATGCGCGAGCTGGAGCGTGTGCCGACCGTCGTAGCCGGATGCTTCCCGGAAGCCTACCCG
GAGCGCGCCCGCAAGCTCCGCCCGGACGCTGCTCTCGTAGGCCCCCGACACCTCGACCGCATACCGGAAGCCGTTCGAGC
CGTGCTGCGCGGCGATCGAGTGGAGTTCCTGGGTGAACGTGAAGACATCGACTGGAAGGCCGACGCTCCCCGTGAGCTGC
CTAACCTCGCCGCCATCGTACCGATCGCGGAGGGCTGTCCGAACAGATGCGCGTACTGCGCCGTGAAGCTCGCACGTGGG
AACCTCCGCAGCTTTCCCCCGGAGCGCATCCTGCGGCGTGTGAAGCGGGAGCTGGAGCGCGGAGCCGTCGAGATTCACCT
CACCGCACAGGACACCGCGACGTACGGACTGGACCGGGGGACGAACGTCGTCGAGCTGCTGGAGGACGTGGTCGATCTCT
GCTCGCGCTACGGCGCCCGGGTTCGCCTGGGTATGTTCAACCCCGGTCACGCTTATCCCATCTCGGACGACCTCGCCGAC
CTCTTCGCTAGCCGAGACGACGTGCTGTACCGTTCCATCCACATGCCCGTGCAGAGCGGTGACGACGAGGTGCTGCGTCG
TATGAACCGGAACTACACGGTCGAAGAGGCCTTGGAGGTGTACCGTGCCTTCGAGCGCCGACTCGGGTACTTCTCCTTCA
TCACGGACGTCATCGTGGGGTTCCCGGGGGAGACCGAGGAGGCCTTCCGTAACACCCTCAGGTTCCTGGAGAGGACCCGA
CCGCACATCCTGCACGCTTCCAGGTTCTGCCGACGCCCCGGGACTCCGGCGGCGCGGATGGAGGATCAGGTCCCGGAGGA
CGTGAAGCTACGGAGGAGCCGAATCCTTCACCGCAAGCGCCTCGAGTGGGCCGAGGAGGCGAACCGCGAGCTGATCGGAG
AGACCGTAGAGGTGACGATGGTAATGGAGAAGTGGGGACGGGACGAGCACGCGAAGAAGACGGTGTTCCGGGGCGAAGTC
CCGGAACCCGGCGAGCGGTTGGAGTGTCGTATCGTGGACGCGTCTCACGCACGACTCGTGGCGGAGGTATGA

Upstream 100 bases:

>100_bases
GGATGTACTGGAGGATCAGCAGGGAGGCTTACCGAGTAGTAGCCTACAACGCGTTCGTTTCGTACGTCACGGAAATACCG
AGACGCTGGGGGTGATAACG

Downstream 100 bases:

>100_bases
GGTCGGCGAGTACAGCCCTCTTCATCGCGAACGCTCCGTTCGCAACCGATCGTCATCCGATTCCGACCCGTGGTCGATCC
GTGGCGGGTTGGTGTCCGGA

Product: 2-methylthioadenine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTKVAVEVYGCAANHDDGRLVRELLRREGFEVVEDAENADVAVLLTCIVRDSVDARMVNRMRELERVPTVVAGCFPEAYP
ERARKLRPDAALVGPRHLDRIPEAVRAVLRGDRVEFLGEREDIDWKADAPRELPNLAAIVPIAEGCPNRCAYCAVKLARG
NLRSFPPERILRRVKRELERGAVEIHLTAQDTATYGLDRGTNVVELLEDVVDLCSRYGARVRLGMFNPGHAYPISDDLAD
LFASRDDVLYRSIHMPVQSGDDEVLRRMNRNYTVEEALEVYRAFERRLGYFSFITDVIVGFPGETEEAFRNTLRFLERTR
PHILHASRFCRRPGTPAARMEDQVPEDVKLRRSRILHRKRLEWAEEANRELIGETVEVTMVMEKWGRDEHAKKTVFRGEV
PEPGERLECRIVDASHARLVAEV

Sequences:

>Translated_423_residues
MTKVAVEVYGCAANHDDGRLVRELLRREGFEVVEDAENADVAVLLTCIVRDSVDARMVNRMRELERVPTVVAGCFPEAYP
ERARKLRPDAALVGPRHLDRIPEAVRAVLRGDRVEFLGEREDIDWKADAPRELPNLAAIVPIAEGCPNRCAYCAVKLARG
NLRSFPPERILRRVKRELERGAVEIHLTAQDTATYGLDRGTNVVELLEDVVDLCSRYGARVRLGMFNPGHAYPISDDLAD
LFASRDDVLYRSIHMPVQSGDDEVLRRMNRNYTVEEALEVYRAFERRLGYFSFITDVIVGFPGETEEAFRNTLRFLERTR
PHILHASRFCRRPGTPAARMEDQVPEDVKLRRSRILHRKRLEWAEEANRELIGETVEVTMVMEKWGRDEHAKKTVFRGEV
PEPGERLECRIVDASHARLVAEV
>Mature_422_residues
TKVAVEVYGCAANHDDGRLVRELLRREGFEVVEDAENADVAVLLTCIVRDSVDARMVNRMRELERVPTVVAGCFPEAYPE
RARKLRPDAALVGPRHLDRIPEAVRAVLRGDRVEFLGEREDIDWKADAPRELPNLAAIVPIAEGCPNRCAYCAVKLARGN
LRSFPPERILRRVKRELERGAVEIHLTAQDTATYGLDRGTNVVELLEDVVDLCSRYGARVRLGMFNPGHAYPISDDLADL
FASRDDVLYRSIHMPVQSGDDEVLRRMNRNYTVEEALEVYRAFERRLGYFSFITDVIVGFPGETEEAFRNTLRFLERTRP
HILHASRFCRRPGTPAARMEDQVPEDVKLRRSRILHRKRLEWAEEANRELIGETVEVTMVMEKWGRDEHAKKTVFRGEVP
EPGERLECRIVDASHARLVAEV

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=411, Percent_Identity=33.0900243309002, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI28872784, Length=452, Percent_Identity=28.3185840707965, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI28872782, Length=452, Percent_Identity=28.3185840707965, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1786882, Length=446, Percent_Identity=29.1479820627803, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787057, Length=390, Percent_Identity=28.2051282051282, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17553146, Length=470, Percent_Identity=29.7872340425532, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71996771, Length=364, Percent_Identity=27.1978021978022, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19922432, Length=438, Percent_Identity=31.9634703196347, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21356207, Length=421, Percent_Identity=27.3159144893112, Blast_Score=138, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48361; Mature: 48230

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50926 TRAM ; PS00290 IG_MHC ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVAVEVYGCAANHDDGRLVRELLRREGFEVVEDAENADVAVLLTCIVRDSVDARMVNR
CCEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
MRELERVPTVVAGCFPEAYPERARKLRPDAALVGPRHLDRIPEAVRAVLRGDRVEFLGER
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCC
EDIDWKADAPRELPNLAAIVPIAEGCPNRCAYCAVKLARGNLRSFPPERILRRVKRELER
CCCCCCCCCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GAVEIHLTAQDTATYGLDRGTNVVELLEDVVDLCSRYGARVRLGMFNPGHAYPISDDLAD
CCEEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHH
LFASRDDVLYRSIHMPVQSGDDEVLRRMNRNYTVEEALEVYRAFERRLGYFSFITDVIVG
HHHCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPGETEEAFRNTLRFLERTRPHILHASRFCRRPGTPAARMEDQVPEDVKLRRSRILHRKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
LEWAEEANRELIGETVEVTMVMEKWGRDEHAKKTVFRGEVPEPGERLECRIVDASHARLV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHCCHH
AEV
CCC
>Mature Secondary Structure 
TKVAVEVYGCAANHDDGRLVRELLRREGFEVVEDAENADVAVLLTCIVRDSVDARMVNR
CEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
MRELERVPTVVAGCFPEAYPERARKLRPDAALVGPRHLDRIPEAVRAVLRGDRVEFLGER
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCC
EDIDWKADAPRELPNLAAIVPIAEGCPNRCAYCAVKLARGNLRSFPPERILRRVKRELER
CCCCCCCCCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GAVEIHLTAQDTATYGLDRGTNVVELLEDVVDLCSRYGARVRLGMFNPGHAYPISDDLAD
CCEEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHH
LFASRDDVLYRSIHMPVQSGDDEVLRRMNRNYTVEEALEVYRAFERRLGYFSFITDVIVG
HHHCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPGETEEAFRNTLRFLERTRPHILHASRFCRRPGTPAARMEDQVPEDVKLRRSRILHRKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
LEWAEEANRELIGETVEVTMVMEKWGRDEHAKKTVFRGEVPEPGERLECRIVDASHARLV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHCCHH
AEV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]