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The map label for this gene is 20094496

Identifier: 20094496

GI number: 20094496

Start: 1028915

End: 1029487

Strand: Direct

Name: 20094496

Synonym: MK1060

Alternate gene names: NA

Gene position: 1028915-1029487 (Clockwise)

Preceding gene: 20094494

Following gene: 20094497

Centisome position: 60.7

GC content: 62.48

Gene sequence:

>573_bases
TTGAAGATCGCGATCACGGGCACGCCGGGTGTCGGGAAGACGACGGTGTGTGAGGCACTCCGTGATCTCGGGTTCGACGT
GGTGCACTTGAATAAGGTCGCGCGGGAGATGGACGCGATCCTCGAGGAGGACGAGCAACGTCAGGCTAAGGTGGTGGATC
TTCACGCGCTCAGGCGGTACGTGGAGGAGTGGGAACCTGAGTCCGATCCGGCGTTCGTGGAGTCTCATTACGCCCACTTG
ATGCCGACGGACCTCGTGATAGTCCTCCGACTTCATCCCTCGGAGCTGGAGCGACGACTGAAGGAAAAGGGTTACCCGCC
CGAGAAGATCGCGGAGAACCTGGAGGCGGAGTTCGTCGGTGTCTGTTACGGGGAAGCCGTGGAAGTACGGTCCGAAGGAT
GCTTCATCCGACCGCCGGAGGACGTGATCCAGGTGAACGTCACGGGCTTGAGCCGCGCCGAGGCGGCCGATCGGGTCCTC
GAGGCCGTGAACCACCGTCGGGGTGACGACGTGGACTGGCTCTCCGACGAGGAGGCGCAACGGACAGTCGAGCGTTACCT
GAAGTACCGATGA

Upstream 100 bases:

>100_bases
GTCCCCACTTGAGTACGCGTTCGGCTAACATCTGCATTCGGGGGAATCCCCCGTCATTTAACCCCCGAGACTGACCGGTT
CGCCGGGGAGGTGATACGGG

Downstream 100 bases:

>100_bases
GGGGGTCGAAGCGTGCGCCGGCGGGAGGTACTGCGTCCGCTGAGGGAGGACGACAAGTACCGCCACCCGGCGGTGTTGGA
CGAGGGGGTCAAGATAATAG

Product: nucleotide kinase related to CMP and AMP kinase

Products: NA

Alternate protein names: ATP-AMP transphosphorylase

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKIAITGTPGVGKTTVCEALRDLGFDVVHLNKVAREMDAILEEDEQRQAKVVDLHALRRYVEEWEPESDPAFVESHYAHL
MPTDLVIVLRLHPSELERRLKEKGYPPEKIAENLEAEFVGVCYGEAVEVRSEGCFIRPPEDVIQVNVTGLSRAEAADRVL
EAVNHRRGDDVDWLSDEEAQRTVERYLKYR

Sequences:

>Translated_190_residues
MKIAITGTPGVGKTTVCEALRDLGFDVVHLNKVAREMDAILEEDEQRQAKVVDLHALRRYVEEWEPESDPAFVESHYAHL
MPTDLVIVLRLHPSELERRLKEKGYPPEKIAENLEAEFVGVCYGEAVEVRSEGCFIRPPEDVIQVNVTGLSRAEAADRVL
EAVNHRRGDDVDWLSDEEAQRTVERYLKYR
>Mature_190_residues
MKIAITGTPGVGKTTVCEALRDLGFDVVHLNKVAREMDAILEEDEQRQAKVVDLHALRRYVEEWEPESDPAFVESHYAHL
MPTDLVIVLRLHPSELERRLKEKGYPPEKIAENLEAEFVGVCYGEAVEVRSEGCFIRPPEDVIQVNVTGLSRAEAADRVL
EAVNHRRGDDVDWLSDEEAQRTVERYLKYR

Specific function: Unknown

COG id: COG1936

COG function: function code F; Predicted nucleotide kinase (related to CMP and AMP kinases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenylate kinase family. AK6 subfamily

Homologues:

Organism=Caenorhabditis elegans, GI17532769, Length=136, Percent_Identity=33.8235294117647, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320035, Length=163, Percent_Identity=33.1288343558282, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KAD6_METKA (Q8TWH4)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614343.1
- ProteinModelPortal:   Q8TWH4
- SMR:   Q8TWH4
- GeneID:   1477161
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1060
- NMPDR:   fig|190192.1.peg.1056
- HOGENOM:   HBG646389
- OMA:   AFVESHY
- BioCyc:   MKAN190192:MK1060-MONOMER
- BRENDA:   2.7.4.3
- HAMAP:   MF_00039
- InterPro:   IPR020618
- InterPro:   IPR001977

Pfam domain/function: PF01121 CoaE

EC number: =2.7.4.3

Molecular weight: Translated: 21696; Mature: 21696

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAITGTPGVGKTTVCEALRDLGFDVVHLNKVAREMDAILEEDEQRQAKVVDLHALRRY
CEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VEEWEPESDPAFVESHYAHLMPTDLVIVLRLHPSELERRLKEKGYPPEKIAENLEAEFVG
HHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHE
VCYGEAVEVRSEGCFIRPPEDVIQVNVTGLSRAEAADRVLEAVNHRRGDDVDWLSDEEAQ
EECCCHHHHCCCCCEECCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RTVERYLKYR
HHHHHHHCCC
>Mature Secondary Structure
MKIAITGTPGVGKTTVCEALRDLGFDVVHLNKVAREMDAILEEDEQRQAKVVDLHALRRY
CEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VEEWEPESDPAFVESHYAHLMPTDLVIVLRLHPSELERRLKEKGYPPEKIAENLEAEFVG
HHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHE
VCYGEAVEVRSEGCFIRPPEDVIQVNVTGLSRAEAADRVLEAVNHRRGDDVDWLSDEEAQ
EECCCHHHHCCCCCEECCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RTVERYLKYR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014